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Items: 1 to 20 of 105

1.

TDR Targets: a chemogenomics resource for neglected diseases.

Magariños MP, Carmona SJ, Crowther GJ, Ralph SA, Roos DS, Shanmugam D, Van Voorhis WC, Agüero F.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1118-27. doi: 10.1093/nar/gkr1053. Epub 2011 Nov 23.

2.

Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

Crowther GJ, Shanmugam D, Carmona SJ, Doyle MA, Hertz-Fowler C, Berriman M, Nwaka S, Ralph SA, Roos DS, Van Voorhis WC, Agüero F.

PLoS Negl Trop Dis. 2010 Aug 24;4(8):e804. doi: 10.1371/journal.pntd.0000804.

3.

Genomic-scale prioritization of drug targets: the TDR Targets database.

Agüero F, Al-Lazikani B, Aslett M, Berriman M, Buckner FS, Campbell RK, Carmona S, Carruthers IM, Chan AW, Chen F, Crowther GJ, Doyle MA, Hertz-Fowler C, Hopkins AL, McAllister G, Nwaka S, Overington JP, Pain A, Paolini GV, Pieper U, Ralph SA, Riechers A, Roos DS, Sali A, Shanmugam D, Suzuki T, Van Voorhis WC, Verlinde CL.

Nat Rev Drug Discov. 2008 Nov;7(11):900-7. doi: 10.1038/nrd2684. Epub 2008 Oct 17. Review.

4.

Collation and data-mining of literature bioactivity data for drug discovery.

Bellis LJ, Akhtar R, Al-Lazikani B, Atkinson F, Bento AP, Chambers J, Davies M, Gaulton A, Hersey A, Ikeda K, Krüger FA, Light Y, McGlinchey S, Santos R, Stauch B, Overington JP.

Biochem Soc Trans. 2011 Oct;39(5):1365-70. doi: 10.1042/BST0391365.

PMID:
21936816
5.

A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases.

Berenstein AJ, Magariños MP, Chernomoretz A, Agüero F.

PLoS Negl Trop Dis. 2016 Jan 6;10(1):e0004300. doi: 10.1371/journal.pntd.0004300. eCollection 2016 Jan.

6.

HelmCoP: an online resource for helminth functional genomics and drug and vaccine targets prioritization.

Abubucker S, Martin J, Taylor CM, Mitreva M.

PLoS One. 2011;6(7):e21832. doi: 10.1371/journal.pone.0021832. Epub 2011 Jul 8.

7.

STITCH: interaction networks of chemicals and proteins.

Kuhn M, von Mering C, Campillos M, Jensen LJ, Bork P.

Nucleic Acids Res. 2008 Jan;36(Database issue):D684-8. Epub 2007 Dec 15.

8.

KEGG for linking genomes to life and the environment.

Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, Yamanishi Y.

Nucleic Acids Res. 2008 Jan;36(Database issue):D480-4. Epub 2007 Dec 12.

9.

ChEMBL: a large-scale bioactivity database for drug discovery.

Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1100-7. doi: 10.1093/nar/gkr777. Epub 2011 Sep 23.

10.

GLIDA: GPCR-ligand database for chemical genomic drug discovery.

Okuno Y, Yang J, Taneishi K, Yabuuchi H, Tsujimoto G.

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D673-7.

11.

From genomics to chemical genomics: new developments in KEGG.

Kanehisa M, Goto S, Hattori M, Aoki-Kinoshita KF, Itoh M, Kawashima S, Katayama T, Araki M, Hirakawa M.

Nucleic Acids Res. 2006 Jan 1;34(Database issue):D354-7.

12.

A chemogenomics view on protein-ligand spaces.

Strömbergsson H, Kleywegt GJ.

BMC Bioinformatics. 2009 Jun 16;10 Suppl 6:S13. doi: 10.1186/1471-2105-10-S6-S13.

13.

SuperTarget goes quantitative: update on drug-target interactions.

Hecker N, Ahmed J, von Eichborn J, Dunkel M, Macha K, Eckert A, Gilson MK, Bourne PE, Preissner R.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1113-7. doi: 10.1093/nar/gkr912. Epub 2011 Nov 8.

14.

GLIDA: GPCR--ligand database for chemical genomics drug discovery--database and tools update.

Okuno Y, Tamon A, Yabuuchi H, Niijima S, Minowa Y, Tonomura K, Kunimoto R, Feng C.

Nucleic Acids Res. 2008 Jan;36(Database issue):D907-12. Epub 2007 Nov 5.

15.

DGIdb 2.0: mining clinically relevant drug-gene interactions.

Wagner AH, Coffman AC, Ainscough BJ, Spies NC, Skidmore ZL, Campbell KM, Krysiak K, Pan D, McMichael JF, Eldred JM, Walker JR, Wilson RK, Mardis ER, Griffith M, Griffith OL.

Nucleic Acids Res. 2016 Jan 4;44(D1):D1036-44. doi: 10.1093/nar/gkv1165. Epub 2015 Nov 3.

16.

Predicting new indications for approved drugs using a proteochemometric method.

Dakshanamurthy S, Issa NT, Assefnia S, Seshasayee A, Peters OJ, Madhavan S, Uren A, Brown ML, Byers SW.

J Med Chem. 2012 Aug 9;55(15):6832-48. doi: 10.1021/jm300576q. Epub 2012 Jul 25.

17.

In silico repositioning of approved drugs for rare and neglected diseases.

Ekins S, Williams AJ, Krasowski MD, Freundlich JS.

Drug Discov Today. 2011 Apr;16(7-8):298-310. doi: 10.1016/j.drudis.2011.02.016. Epub 2011 Mar 1. Review.

PMID:
21376136
18.

The ChEMBL bioactivity database: an update.

Bento AP, Gaulton A, Hersey A, Bellis LJ, Chambers J, Davies M, Krüger FA, Light Y, Mak L, McGlinchey S, Nowotka M, Papadatos G, Santos R, Overington JP.

Nucleic Acids Res. 2014 Jan;42(Database issue):D1083-90. doi: 10.1093/nar/gkt1031. Epub 2013 Nov 7.

19.

The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands.

Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, Davenport AP, McGrath JC, Peters JA, Southan C, Spedding M, Yu W, Harmar AJ; NC-IUPHAR..

Nucleic Acids Res. 2014 Jan;42(Database issue):D1098-106. doi: 10.1093/nar/gkt1143. Epub 2013 Nov 14.

20.

ChemMine tools: an online service for analyzing and clustering small molecules.

Backman TW, Cao Y, Girke T.

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W486-91. doi: 10.1093/nar/gkr320. Epub 2011 May 16.

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