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Items: 1 to 20 of 153

1.

Deletion of the SPARC acidic domain or EGF-like module reduces SPARC-induced migration and signaling through p38 MAPK/HSP27 in glioma.

McClung HM, Golembieski WA, Schultz CR, Jankowski M, Schultz LR, Rempel SA.

Carcinogenesis. 2012 Feb;33(2):275-84. doi: 10.1093/carcin/bgr276. Epub 2011 Nov 23.

2.

HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion.

Golembieski WA, Thomas SL, Schultz CR, Yunker CK, McClung HM, Lemke N, Cazacu S, Barker T, Sage EH, Brodie C, Rempel SA.

Glia. 2008 Aug 1;56(10):1061-75. doi: 10.1002/glia.20679.

PMID:
18442089
3.

PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in glioma.

Alam R, Schultz CR, Golembieski WA, Poisson LM, Rempel SA.

Neuro Oncol. 2013 Apr;15(4):451-61. doi: 10.1093/neuonc/nos326. Epub 2013 Feb 3.

4.

Inhibition of HSP27 alone or in combination with pAKT inhibition as therapeutic approaches to target SPARC-induced glioma cell survival.

Schultz CR, Golembieski WA, King DA, Brown SL, Brodie C, Rempel SA.

Mol Cancer. 2012 Apr 5;11:20. doi: 10.1186/1476-4598-11-20.

5.

SPARC modulates cell growth, attachment and migration of U87 glioma cells on brain extracellular matrix proteins.

Rempel SA, Golembieski WA, Fisher JL, Maile M, Nakeff A.

J Neurooncol. 2001 Jun;53(2):149-60.

PMID:
11716067
6.

PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.

Thomas SL, Alam R, Lemke N, Schultz LR, Gutiérrez JA, Rempel SA.

Neuro Oncol. 2010 Sep;12(9):941-55. doi: 10.1093/neuonc/noq048. Epub 2010 May 14.

7.

Slow binding kinetics of secreted protein, acidic, rich in cysteine-VEGF interaction limit VEGF activation of VEGF receptor 2 and attenuate angiogenesis.

Cydzik M, Abdul-Wahid A, Park S, Bourdeau A, Bowden K, Prodeus A, Kollara A, Brown TJ, Ringuette MJ, Gariépy J.

FASEB J. 2015 Aug;29(8):3493-505. doi: 10.1096/fj.15-271775. Epub 2015 Apr 28.

8.

cDNA array analysis of SPARC-modulated changes in glioma gene expression.

Golembieski WA, Rempel SA.

J Neurooncol. 2002 Dec;60(3):213-26.

PMID:
12510773
9.

Knockdown of secreted protein acidic and rich in cysteine (SPARC) expression diminishes radiosensitivity of glioma cells.

Liu H, Zhang H, Jiang X, Ma Y, Xu Y, Feng S, Liu F.

Cancer Biother Radiopharm. 2011 Dec;26(6):705-15. doi: 10.1089/cbr.2011.0987.

PMID:
22145659
10.

Downregulation of SPARC expression inhibits cell migration and invasion in malignant gliomas.

Seno T, Harada H, Kohno S, Teraoka M, Inoue A, Ohnishi T.

Int J Oncol. 2009 Mar;34(3):707-15.

PMID:
19212676
11.
13.
14.

Phosphorylation of heat shock protein 27 antagonizes TNF-α induced HeLa cell apoptosis via regulating TAK1 ubiquitination and activation of p38 and ERK signaling.

Qi Z, Shen L, Zhou H, Jiang Y, Lan L, Luo L, Yin Z.

Cell Signal. 2014 Jul;26(7):1616-25. doi: 10.1016/j.cellsig.2014.03.015. Epub 2014 Mar 29.

PMID:
24686082
15.

Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases.

Shi Q, Bao S, Song L, Wu Q, Bigner DD, Hjelmeland AB, Rich JN.

Oncogene. 2007 Jun 14;26(28):4084-94. Epub 2007 Jan 8.

PMID:
17213807
16.

Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling.

Frey MR, Golovin A, Polk DB.

J Biol Chem. 2004 Oct 22;279(43):44513-21. Epub 2004 Aug 16.

17.

Autocrine control of glioma cells adhesion and migration through IRE1α-mediated cleavage of SPARC mRNA.

Dejeans N, Pluquet O, Lhomond S, Grise F, Bouchecareilh M, Juin A, Meynard-Cadars M, Bidaud-Meynard A, Gentil C, Moreau V, Saltel F, Chevet E.

J Cell Sci. 2012 Sep 15;125(Pt 18):4278-87. doi: 10.1242/jcs.099291. Epub 2012 Jun 20.

18.

Epidermal growth factor-dependent cyclooxygenase-2 induction in gliomas requires protein kinase C-delta.

Xu K, Chang CM, Gao H, Shu HK.

Oncogene. 2009 Mar 19;28(11):1410-20. doi: 10.1038/onc.2008.500. Epub 2009 Jan 26.

PMID:
19169273
19.

miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway.

Yang F, Yin Y, Wang F, Wang Y, Zhang L, Tang Y, Sun S.

Hepatology. 2010 May;51(5):1614-23. doi: 10.1002/hep.23566.

PMID:
20209605
20.

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