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Items: 1 to 20 of 100

1.

Immunity to ricin: fundamental insights into toxin-antibody interactions.

O'Hara JM, Yermakova A, Mantis NJ.

Curr Top Microbiol Immunol. 2012;357:209-41. doi: 10.1007/82_2011_193. Review.

2.

Folding domains within the ricin toxin A subunit as targets of protective antibodies.

O'Hara JM, Neal LM, McCarthy EA, Kasten-Jolly JA, Brey RN 3rd, Mantis NJ.

Vaccine. 2010 Oct 8;28(43):7035-46. doi: 10.1016/j.vaccine.2010.08.020. Epub 2010 Aug 18.

3.

Localization of non-linear neutralizing B cell epitopes on ricin toxin's enzymatic subunit (RTA).

O'Hara JM, Kasten-Jolly JC, Reynolds CE, Mantis NJ.

Immunol Lett. 2014 Mar-Apr;158(1-2):7-13. doi: 10.1016/j.imlet.2013.11.009. Epub 2013 Nov 21.

4.

Neutralizing monoclonal antibodies against ricin's enzymatic subunit interfere with protein disulfide isomerase-mediated reduction of ricin holotoxin in vitro.

O'Hara JM, Mantis NJ.

J Immunol Methods. 2013 Sep 30;395(1-2):71-8. doi: 10.1016/j.jim.2013.06.004. Epub 2013 Jun 15.

5.

Sub-domains of ricin's B subunit as targets of toxin neutralizing and non-neutralizing monoclonal antibodies.

Yermakova A, Vance DJ, Mantis NJ.

PLoS One. 2012;7(9):e44317. doi: 10.1371/journal.pone.0044317. Epub 2012 Sep 11.

6.

Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.

Rudolph MJ, Vance DJ, Cassidy MS, Rong Y, Shoemaker CB, Mantis NJ.

Proteins. 2016 Aug;84(8):1162-72. doi: 10.1002/prot.25062. Epub 2016 Jun 15.

PMID:
27159829
7.

Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB).

Herrera C, Vance DJ, Eisele LE, Shoemaker CB, Mantis NJ.

PLoS One. 2014 Jun 11;9(6):e99788. doi: 10.1371/journal.pone.0099788. eCollection 2014.

8.

Protective immunity to ricin toxin conferred by antibodies against the toxin's binding subunit (RTB).

Yermakova A, Mantis NJ.

Vaccine. 2011 Oct 19;29(45):7925-35. doi: 10.1016/j.vaccine.2011.08.075. Epub 2011 Aug 26.

9.

Neutralizing Monoclonal Antibodies against Disparate Epitopes on Ricin Toxin's Enzymatic Subunit Interfere with Intracellular Toxin Transport.

Yermakova A, Klokk TI, O'Hara JM, Cole R, Sandvig K, Mantis NJ.

Sci Rep. 2016 Mar 7;6:22721. doi: 10.1038/srep22721.

10.

Neutralising antibodies against ricin toxin.

Prigent J, Panigai L, Lamourette P, Sauvaire D, Devilliers K, Plaisance M, Volland H, Créminon C, Simon S.

PLoS One. 2011;6(5):e20166. doi: 10.1371/journal.pone.0020166. Epub 2011 May 25.

11.

Antibody-mediated inhibition of ricin toxin retrograde transport.

Yermakova A, Klokk TI, Cole R, Sandvig K, Mantis NJ.

MBio. 2014 Apr 8;5(2):e00995. doi: 10.1128/mBio.00995-13.

12.

Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.

Rudolph MJ, Vance DJ, Cheung J, Franklin MC, Burshteyn F, Cassidy MS, Gary EN, Herrera C, Shoemaker CB, Mantis NJ.

J Mol Biol. 2014 Aug 26;426(17):3057-68. doi: 10.1016/j.jmb.2014.05.026. Epub 2014 Jun 4.

13.

A monoclonal immunoglobulin G antibody directed against an immunodominant linear epitope on the ricin A chain confers systemic and mucosal immunity to ricin.

Neal LM, O'Hara J, Brey RN 3rd, Mantis NJ.

Infect Immun. 2010 Jan;78(1):552-61. doi: 10.1128/IAI.00796-09. Epub 2009 Oct 26.

14.

Neutralizing activity and protective immunity to ricin toxin conferred by B subunit (RTB)-specific Fab fragments.

Yermakova A, Mantis NJ.

Toxicon. 2013 Sep;72:29-34. doi: 10.1016/j.toxicon.2013.04.005. Epub 2013 Apr 17.

15.

Immunoglobulin A antibodies against ricin A and B subunits protect epithelial cells from ricin intoxication.

Mantis NJ, McGuinness CR, Sonuyi O, Edwards G, Farrant SA.

Infect Immun. 2006 Jun;74(6):3455-62.

16.

Antibody to ricin a chain hinders intracellular routing of toxin and protects cells even after toxin has been internalized.

Song K, Mize RR, Marrero L, Corti M, Kirk JM, Pincus SH.

PLoS One. 2013 Apr 24;8(4):e62417. doi: 10.1371/journal.pone.0062417. Print 2013.

17.
18.

Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.

Rudolph MJ, Vance DJ, Cassidy MS, Rong Y, Mantis NJ.

J Biol Chem. 2017 Jan 20;292(3):872-883. doi: 10.1074/jbc.M116.758102. Epub 2016 Nov 30.

PMID:
27903650
19.

Resolution of two overlapping neutralizing B cell epitopes within a solvent exposed, immunodominant α-helix in ricin toxin's enzymatic subunit.

Vance DJ, Mantis NJ.

Toxicon. 2012 Oct;60(5):874-7. doi: 10.1016/j.toxicon.2012.06.014. Epub 2012 Jun 29.

20.

Conformation-dependent high-affinity potent ricin-neutralizing monoclonal antibodies.

Hu WG, Yin J, Chau D, Hu CC, Lillico D, Yu J, Negrych LM, Cherwonogrodzky JW.

Biomed Res Int. 2013;2013:471346. doi: 10.1155/2013/471346. Epub 2012 Dec 26.

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