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FGF8 is essential for formation of the ductal system in the male reproductive tract.

Kitagaki J, Ueda Y, Chi X, Sharma N, Elder CM, Truffer E, Costantini F, Lewandoski M, Perantoni AO.

Development. 2011 Dec;138(24):5369-78. doi: 10.1242/dev.051888.


Preformed Wolffian duct regulates Müllerian duct elongation independently of canonical Wnt signaling or Lhx1 expression.

Chiga M, Ohmori T, Ohba T, Katabuchi H, Nishinakamura R.

Int J Dev Biol. 2014;58(9):663-8. doi: 10.1387/ijdb.140261rn.


Lhx1 is required in Müllerian duct epithelium for uterine development.

Huang CC, Orvis GD, Kwan KM, Behringer RR.

Dev Biol. 2014 May 15;389(2):124-36. doi: 10.1016/j.ydbio.2014.01.025. Epub 2014 Feb 21.


Androgen receptor expression in developing male reproductive organs.

Cooke PS, Young P, Cunha GR.

Endocrinology. 1991 Jun;128(6):2867-73.


Characterization of Pax-2 regulatory sequences that direct transgene expression in the Wolffian duct and its derivatives.

Kuschert S, Rowitch DH, Haenig B, McMahon AP, Kispert A.

Dev Biol. 2001 Jan 1;229(1):128-40.


Defects of urogenital development in mice lacking Emx2.

Miyamoto N, Yoshida M, Kuratani S, Matsuo I, Aizawa S.

Development. 1997 May;124(9):1653-64.


Differential regulation of two sets of mesonephric tubules by WT-1.

Sainio K, Hellstedt P, Kreidberg JA, Saxén L, Sariola H.

Development. 1997 Apr;124(7):1293-9.


Fgf8 is required for anterior heart field development.

Ilagan R, Abu-Issa R, Brown D, Yang YP, Jiao K, Schwartz RJ, Klingensmith J, Meyers EN.

Development. 2006 Jun;133(12):2435-45.


FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.

Grieshammer U, Cebrián C, Ilagan R, Meyers E, Herzlinger D, Martin GR.

Development. 2005 Sep;132(17):3847-57. Epub 2005 Jul 27.


FGF8 coordinates tissue elongation and cell epithelialization during early kidney tubulogenesis.

Atsuta Y, Takahashi Y.

Development. 2015 Jul 1;142(13):2329-37. doi: 10.1242/dev.122408.


Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development.

Perantoni AO, Timofeeva O, Naillat F, Richman C, Pajni-Underwood S, Wilson C, Vainio S, Dove LF, Lewandoski M.

Development. 2005 Sep;132(17):3859-71. Epub 2005 Jul 27.


Pax-2 controls multiple steps of urogenital development.

Torres M, Gómez-Pardo E, Dressler GR, Gruss P.

Development. 1995 Dec;121(12):4057-65.


Glial cell-derived neurotrophic factor independent ureteric bud outgrowth from the Wolffian duct.

Maeshima A, Sakurai H, Choi Y, Kitamura S, Vaughn DA, Tee JB, Nigam SK.

J Am Soc Nephrol. 2007 Dec;18(12):3147-55. Epub 2007 Nov 14. No abstract available.


Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.

Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A.

Development. 2014 Sep;141(17):3420-30. doi: 10.1242/dev.113928.


Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling.

Park EJ, Ogden LA, Talbot A, Evans S, Cai CL, Black BL, Frank DU, Moon AM.

Development. 2006 Jun;133(12):2419-33.


Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development.

Srinivas S, Wu Z, Chen CM, D'Agati V, Costantini F.

Development. 1999 Apr;126(7):1375-86.


Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract.

Shao X, Somlo S, Igarashi P.

J Am Soc Nephrol. 2002 Jul;13(7):1837-46.


Pkd1 is required for male reproductive tract development.

Nie X, Arend LJ.

Mech Dev. 2013 Nov-Dec;130(11-12):567-76. doi: 10.1016/j.mod.2013.07.006. Epub 2013 Aug 9.

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