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Items: 1 to 20 of 82

1.

Elucidation of mu-Opioid Gene Structure: How Genetics Can Help Predict Responses to Opioids.

Diatchenko L, Robinson JE, Maixner W.

Eur J Pain Suppl. 2011 Nov 11;5(2):433-438.

2.

Expansion of the human mu-opioid receptor gene architecture: novel functional variants.

Shabalina SA, Zaykin DV, Gris P, Ogurtsov AY, Gauthier J, Shibata K, Tchivileva IE, Belfer I, Mishra B, Kiselycznyk C, Wallace MR, Staud R, Spiridonov NA, Max MB, Goldman D, Fillingim RB, Maixner W, Diatchenko L.

Hum Mol Genet. 2009 Mar 15;18(6):1037-51. doi: 10.1093/hmg/ddn439. Epub 2008 Dec 22.

3.

Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon.

Doyle GA, Sheng XR, Lin SS, Press DM, Grice DE, Buono RJ, Ferraro TN, Berrettini WH.

Gene. 2007 Jun 15;395(1-2):98-107. Epub 2007 Feb 20.

4.

A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism.

Gris P, Gauthier J, Cheng P, Gibson DG, Gris D, Laur O, Pierson J, Wentworth S, Nackley AG, Maixner W, Diatchenko L.

Mol Pain. 2010 Jun 2;6:33. doi: 10.1186/1744-8069-6-33.

5.

μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids.

Convertino M, Samoshkin A, Gauthier J, Gold MS, Maixner W, Dokholyan NV, Diatchenko L.

Prog Neuropsychopharmacol Biol Psychiatry. 2015 Oct 1;62:61-7. doi: 10.1016/j.pnpbp.2014.11.009. Epub 2014 Dec 6. Review.

6.

Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling.

Samoshkin A, Convertino M, Viet CT, Wieskopf JS, Kambur O, Marcovitz J, Patel P, Stone LS, Kalso E, Mogil JS, Schmidt BL, Maixner W, Dokholyan NV, Diatchenko L.

Sci Rep. 2015 Dec 11;5:18198. doi: 10.1038/srep18198.

7.

Cellular signalling of non-synonymous single-nucleotide polymorphisms of the human μ-opioid receptor (OPRM1).

Knapman A, Connor M.

Br J Pharmacol. 2015 Jan;172(2):349-63. doi: 10.1111/bph.12644. Epub 2014 Jul 1. Review.

8.

Identification of three mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon.

Doyle GA, Rebecca Sheng X, Lin SS, Press DM, Grice DE, Buono RJ, Ferraro TN, Berrettini WH.

Gene. 2007 Feb 15;388(1-2):135-47. Epub 2006 Nov 1.

PMID:
17156941
9.

Genetic dissociation of morphine analgesia from hyperalgesia in mice.

Marrone GF, Le Rouzic V, Varadi A, Xu J, Rajadhyaksha AM, Majumdar S, Pan YX, Pasternak GW.

Psychopharmacology (Berl). 2017 Jun;234(12):1891-1900. doi: 10.1007/s00213-017-4600-2. Epub 2017 Mar 25.

PMID:
28343361
10.

A new splice of life for the μ-opioid receptor.

Iadarola MJ, Sapio MR, Mannes AJ.

J Clin Invest. 2015 Jul 1;125(7):2558-61. doi: 10.1172/JCI82060. Epub 2015 May 26.

11.

Mu opioid receptor gene variants: lack of association with alcohol dependence.

Bergen AW, Kokoszka J, Peterson R, Long JC, Virkkunen M, Linnoila M, Goldman D.

Mol Psychiatry. 1997 Oct-Nov;2(6):490-4.

PMID:
9399694
12.

Opioid-induced redistribution of 6TM and 7TM μ opioid receptors: A hypothesized mechanistic facilitator model of opioid-induced hyperalgesia.

Wang W, Wang Y, Zhang W, Jin X, Liu Y, Xu S, Lei L, Shen X, Guo X, Xia X, Wang F.

Pharmacol Rep. 2016 Aug;68(4):686-91. doi: 10.1016/j.pharep.2016.03.003. Epub 2016 Mar 19. Review.

PMID:
27116700
13.

Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis.

Coller JK, Beardsley J, Bignold J, Li Y, Merg F, Sullivan T, Cox TC, Somogyi AA.

Pharmgenomics Pers Med. 2009;2:9-19. Epub 2009 Mar 20.

14.

Genetic variation in the behavioral effects of buprenorphine in female mice derived from a murine model of the OPRM1 A118G polymorphism.

Browne CA, Erickson RL, Blendy JA, Lucki I.

Neuropharmacology. 2017 May 1;117:401-407. doi: 10.1016/j.neuropharm.2017.02.005. Epub 2017 Feb 7.

PMID:
28188737
15.

Differential expression of the alternatively spliced OPRM1 isoform μ-opioid receptor-1K in HIV-infected individuals.

Dever SM, Costin BN, Xu R, El-Hage N, Balinang J, Samoshkin A, O'Brien MA, McRae M, Diatchenko L, Knapp PE, Hauser KF.

AIDS. 2014 Jan 2;28(1):19-30. doi: 10.1097/QAD.0000000000000113.

16.

OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models.

Mague SD, Blendy JA.

Drug Alcohol Depend. 2010 May 1;108(3):172-82. doi: 10.1016/j.drugalcdep.2009.12.016. Epub 2010 Jan 13. Review.

17.

Human Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers.

Ray R, Ruparel K, Newberg A, Wileyto EP, Loughead JW, Divgi C, Blendy JA, Logan J, Zubieta JK, Lerman C.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9268-73. doi: 10.1073/pnas.1018699108. Epub 2011 May 16.

18.

The N-terminally truncated µ3 and µ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene.

Andersen S, Baar C, Fladvad T, Laugsand EA, Skorpen F.

PLoS One. 2013 Aug 12;8(8):e71024. doi: 10.1371/journal.pone.0071024. eCollection 2013.

19.

The role of hydromorphone and OPRM1 in postoperative pain relief with hydrocodone.

Boswell MV, Stauble ME, Loyd GE, Langman L, Ramey-Hartung B, Baumgartner RN, Tucker WW, Jortani SA.

Pain Physician. 2013 May-Jun;16(3):E227-35.

20.

Mouse model of OPRM1 (A118G) polymorphism has altered hippocampal function.

Mague SD, Port RG, McMullen ME, Carlson GC, Turner JR.

Neuropharmacology. 2015 Oct;97:426-35. doi: 10.1016/j.neuropharm.2015.04.032. Epub 2015 May 15.

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