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Ubiquitination of Notch1 is regulated by MAML1-mediated p300 acetylation of Notch1.

Popko-Scibor AE, Lindberg MJ, Hansson ML, Holmlund T, Wallberg AE.

Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):300-6. doi: 10.1016/j.bbrc.2011.11.030. Epub 2011 Nov 12.


A proline repeat domain in the Notch co-activator MAML1 is important for the p300-mediated acetylation of MAML1.

Saint Just Ribeiro M, Hansson ML, Wallberg AE.

Biochem J. 2007 Jun 1;404(2):289-98.


The transcriptional coactivator MAML1 regulates p300 autoacetylation and HAT activity.

Hansson ML, Popko-Scibor AE, Saint Just Ribeiro M, Dancy BM, Lindberg MJ, Cole PA, Wallberg AE.

Nucleic Acids Res. 2009 May;37(9):2996-3006. doi: 10.1093/nar/gkp163. Epub 2009 Mar 20.


Transcriptional mechanisms by the coregulator MAML1.

Saint Just Ribeiro M, Wallberg AE.

Curr Protein Pept Sci. 2009 Dec;10(6):570-6. Review.


MAML1 acts cooperatively with EGR1 to activate EGR1-regulated promoters: implications for nephrogenesis and the development of renal cancer.

Hansson ML, Behmer S, Ceder R, Mohammadi S, Preta G, Grafström RC, Fadeel B, Wallberg AE.

PLoS One. 2012;7(9):e46001. doi: 10.1371/journal.pone.0046001. Epub 2012 Sep 27.


Mastermind-Like 1 Is Ubiquitinated: Functional Consequences for Notch Signaling.

Farshbaf M, Lindberg MJ, Truong A, Bevens Z, Chambers E, Pournara A, Wallberg AE, White JB.

PLoS One. 2015 Jul 30;10(7):e0134013. doi: 10.1371/journal.pone.0134013. eCollection 2015.


Acetylation of Mastermind-like 1 by p300 Drives the Recruitment of NACK to Initiate Notch-Dependent Transcription.

Jin K, Zhou W, Han X, Wang Z, Li B, Jeffries S, Tao W, Robbins DJ, Capobianco AJ.

Cancer Res. 2017 Aug 15;77(16):4228-4237. doi: 10.1158/0008-5472.CAN-16-3156. Epub 2017 Jun 16.


Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins.

Furia B, Deng L, Wu K, Baylor S, Kehn K, Li H, Donnelly R, Coleman T, Kashanchi F.

J Biol Chem. 2002 Feb 15;277(7):4973-80. Epub 2001 Dec 5.


Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors.

Giandomenico V, Simonsson M, Grönroos E, Ericsson J.

Mol Cell Biol. 2003 Apr;23(7):2587-99.


Acetylation of HIV-1 integrase by p300 regulates viral integration.

Cereseto A, Manganaro L, Gutierrez MI, Terreni M, Fittipaldi A, Lusic M, Marcello A, Giacca M.

EMBO J. 2005 Sep 7;24(17):3070-81. Epub 2005 Aug 11.


Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1.

Liu ZJ, Xiao M, Balint K, Soma A, Pinnix CC, Capobianco AJ, Velazquez OC, Herlyn M.

FASEB J. 2006 May;20(7):1009-11. Epub 2006 Mar 29.


The transcriptional coactivators p300 and CBP are histone acetyltransferases.

Ogryzko VV, Schiltz RL, Russanova V, Howard BH, Nakatani Y.

Cell. 1996 Nov 29;87(5):953-9.


Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.

McGill MA, McGlade CJ.

J Biol Chem. 2003 Jun 20;278(25):23196-203. Epub 2003 Apr 7.


Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA.

Deng L, Wang D, de la Fuente C, Wang L, Li H, Lee CG, Donnelly R, Wade JD, Lambert P, Kashanchi F.

Virology. 2001 Oct 25;289(2):312-26.


Effects of the SANT domain of tension-induced/inhibited proteins (TIPs), novel partners of the histone acetyltransferase p300, on p300 activity and TIP-6-induced adipogenesis.

Badri KR, Zhou Y, Dhru U, Aramgam S, Schuger L.

Mol Cell Biol. 2008 Oct;28(20):6358-72. doi: 10.1128/MCB.00333-08. Epub 2008 Aug 18.


Autoimmune regulator is acetylated by transcription coactivator CBP/p300.

Saare M, Rebane A, Rajashekar B, Vilo J, Peterson P.

Exp Cell Res. 2012 Aug 15;318(14):1767-78. doi: 10.1016/j.yexcr.2012.04.013. Epub 2012 May 30.


GSK3beta is a negative regulator of the transcriptional coactivator MAML1.

Saint Just Ribeiro M, Hansson ML, Lindberg MJ, Popko-Scibor AE, Wallberg AE.

Nucleic Acids Res. 2009 Nov;37(20):6691-700. doi: 10.1093/nar/gkp724. Epub 2009 Sep 8.


Acetylation of the BETA2 transcription factor by p300-associated factor is important in insulin gene expression.

Qiu Y, Guo M, Huang S, Stein R.

J Biol Chem. 2004 Mar 12;279(11):9796-802. Epub 2003 Dec 30.

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