Similar articles for PMID: 22100260

Year	Number of Results
2000	1
2001	1
2002	1
2003	1
2004	1
2005	1
2006	8
2007	5
2008	4
2009	10
2010	11
2011	15
2012	8
2013	4
2014	3
2015	2
2016	3
2017	1
2018	2
2019	5
2020	4
2021	2
2024	0

1

The discovery of UK-369003, a novel PDE5 inhibitor with the potential for oral bioavailability and dose-proportional pharmacokinetics.

Rawson DJ, Ballard S, Barber C, Barker L, Beaumont K, Bunnage M, Cole S, Corless M, Denton S, Ellis D, Floc'h M, Foster L, Gosset J, Holmwood F, Lane C, Leahy D, Mathias J, Maw G, Million W, Poinsard C, Price J, Russel R, Street S, Watson L. Rawson DJ, et al. Bioorg Med Chem. 2012 Jan 1;20(1):498-509. doi: 10.1016/j.bmc.2011.10.022. Epub 2011 Oct 24. Bioorg Med Chem. 2012. PMID: 22100260

2

Critical analysis of the relationship between sexual dysfunctions and lower urinary tract symptoms due to benign prostatic hyperplasia.

Gacci M, Eardley I, Giuliano F, Hatzichristou D, Kaplan SA, Maggi M, McVary KT, Mirone V, Porst H, Roehrborn CG. Gacci M, et al. Eur Urol. 2011 Oct;60(4):809-25. doi: 10.1016/j.eururo.2011.06.037. Epub 2011 Jun 29. Eur Urol. 2011. PMID: 21726934 Review.

3

The mechanism of action of phosphodiesterase type 5 inhibitors in the treatment of lower urinary tract symptoms related to benign prostatic hyperplasia.

Giuliano F, Ückert S, Maggi M, Birder L, Kissel J, Viktrup L. Giuliano F, et al. Eur Urol. 2013 Mar;63(3):506-16. doi: 10.1016/j.eururo.2012.09.006. Epub 2012 Sep 11. Eur Urol. 2013. PMID: 23018163 Review.

4

Phosphodiesterase-5 inhibitors and benign prostatic hyperplasia.

Wang C. Wang C. Curr Opin Urol. 2010 Jan;20(1):49-54. doi: 10.1097/MOU.0b013e328333ac68. Curr Opin Urol. 2010. PMID: 19887943 Review.

5

Application of physiologically based pharmacokinetic modeling to understanding the clinical pharmacokinetics of UK-369,003.

Watson KJ, Davis J, Jones HM. Watson KJ, et al. Drug Metab Dispos. 2011 Jul;39(7):1203-13. doi: 10.1124/dmd.111.038224. Epub 2011 Mar 30. Drug Metab Dispos. 2011. PMID: 21451120

6

[Phosphodiesterase type 5 inhibitors for lower urinary tract symptoms induced by benign prostatic hyperplasia: an update].

He PB, Zha PJ, Xu DP. He PB, et al. Zhonghua Nan Ke Xue. 2014 Jul;20(7):651-6. Zhonghua Nan Ke Xue. 2014. PMID: 25095624 Review. Chinese.

7

Discovery of novel pyrazolopyrimidinone analogs as potent inhibitors of phosphodiesterase type-5.

Sawant SD, Lakshma Reddy G, Dar MI, Srinivas M, Gupta G, Sahu PK, Mahajan P, Nargotra A, Singh S, Sharma SC, Tikoo M, Singh G, Vishwakarma RA, Syed SH. Sawant SD, et al. Bioorg Med Chem. 2015 May 1;23(9):2121-8. doi: 10.1016/j.bmc.2015.03.005. Epub 2015 Mar 9. Bioorg Med Chem. 2015. PMID: 25801159

8

A novel series of potent and selective PDE5 inhibitors with potential for high and dose-independent oral bioavailability.

Allerton CM, Barber CG, Beaumont KC, Brown DG, Cole SM, Ellis D, Lane CA, Maw GN, Mount NM, Rawson DJ, Robinson CM, Street SD, Summerhill NW. Allerton CM, et al. J Med Chem. 2006 Jun 15;49(12):3581-94. doi: 10.1021/jm060113e. J Med Chem. 2006. PMID: 16759100

9

Efficacy and safety of tadalafil once daily in the treatment of men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: results of an international randomized, double-blind, placebo-controlled trial.

Porst H, Kim ED, Casabé AR, Mirone V, Secrest RJ, Xu L, Sundin DP, Viktrup L; LVHJ study team. Porst H, et al. Eur Urol. 2011 Nov;60(5):1105-13. doi: 10.1016/j.eururo.2011.08.005. Epub 2011 Aug 12. Eur Urol. 2011. PMID: 21871706 Clinical Trial.

10

Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5.

Wang G, Liu Z, Chen T, Wang Z, Yang H, Zheng M, Ren J, Tian G, Yang X, Li L, Li J, Suo J, Zhang R, Jiang X, Terrett NK, Shen J, Xu Y, Jiang H. Wang G, et al. J Med Chem. 2012 Dec 13;55(23):10540-50. doi: 10.1021/jm301159y. Epub 2012 Nov 19. J Med Chem. 2012. PMID: 23137303

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