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Items: 1 to 20 of 169

1.

Hepatocyte growth factor/c-met signaling is required for stem-cell-mediated liver regeneration in mice.

Ishikawa T, Factor VM, Marquardt JU, Raggi C, Seo D, Kitade M, Conner EA, Thorgeirsson SS.

Hepatology. 2012 Apr;55(4):1215-26. doi: 10.1002/hep.24796.

2.

Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair.

Huh CG, Factor VM, Sánchez A, Uchida K, Conner EA, Thorgeirsson SS.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4477-82.

3.

Deletion of the Met tyrosine kinase in liver progenitor oval cells increases sensitivity to apoptosis in vitro.

del Castillo G, Factor VM, Fernández M, Alvarez-Barrientos A, Fabregat I, Thorgeirsson SS, Sánchez A.

Am J Pathol. 2008 May;172(5):1238-47. doi: 10.2353/ajpath.2008.070793. Epub 2008 Apr 1.

4.

HGF and SDF-1-mediated mobilization of CD133+ BMSC for hepatic regeneration following extensive liver resection.

Lehwald N, Duhme C, Wildner M, Kuhn S, Fürst G, Forbes SJ, Jonas S, Robson SC, Knoefel WT, Schmelzle M, Schulte Am Esch J.

Liver Int. 2014 Jan;34(1):89-101. doi: 10.1111/liv.12195. Epub 2013 May 23.

PMID:
23701640
5.

HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial-mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway in an in vitro model.

Suárez-Causado A, Caballero-Díaz D, Bertrán E, Roncero C, Addante A, García-Álvaro M, Fernández M, Herrera B, Porras A, Fabregat I, Sánchez A.

Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2453-63. doi: 10.1016/j.bbamcr.2015.05.017. Epub 2015 May 20.

6.

EGFR is dispensable for c-Met-mediated proliferation and survival activities in mouse adult liver oval cells.

Martínez-Palacián A, del Castillo G, Herrera B, Fernández M, Roncero C, Fabregat I, Sánchez A.

Cell Signal. 2012 Feb;24(2):505-13. doi: 10.1016/j.cellsig.2011.09.031. Epub 2011 Oct 7.

PMID:
22001397
7.

Nuclear receptor CAR (NR1I3) is essential for DDC-induced liver injury and oval cell proliferation in mouse liver.

Yamazaki Y, Moore R, Negishi M.

Lab Invest. 2011 Nov;91(11):1624-33. doi: 10.1038/labinvest.2011.115. Epub 2011 Aug 8.

8.

Loss of c-Met accelerates development of liver fibrosis in response to CCl(4) exposure through deregulation of multiple molecular pathways.

Marquardt JU, Seo D, Gómez-Quiroz LE, Uchida K, Gillen MC, Kitade M, Kaposi-Novak P, Conner EA, Factor VM, Thorgeirsson SS.

Biochim Biophys Acta. 2012 Jun;1822(6):942-51. doi: 10.1016/j.bbadis.2012.02.012. Epub 2012 Feb 22.

9.

The biliary epithelium gives rise to liver progenitor cells.

Rodrigo-Torres D, Affò S, Coll M, Morales-Ibanez O, Millán C, Blaya D, Alvarez-Guaita A, Rentero C, Lozano JJ, Maestro MA, Solar M, Arroyo V, Caballería J, van Grunsven LA, Enrich C, Ginès P, Bataller R, Sancho-Bru P.

Hepatology. 2014 Oct;60(4):1367-77. doi: 10.1002/hep.27078. Epub 2014 Aug 21.

10.

Plasmin-mediated proteolysis is required for hepatocyte growth factor activation during liver repair.

Shanmukhappa K, Matte U, Degen JL, Bezerra JA.

J Biol Chem. 2009 May 8;284(19):12917-23. doi: 10.1074/jbc.M807313200. Epub 2009 Mar 13.

11.

Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regeneration.

Mohammed FF, Pennington CJ, Kassiri Z, Rubin JS, Soloway PD, Ruther U, Edwards DR, Khokha R.

Hepatology. 2005 Apr;41(4):857-67.

PMID:
15726641
12.

Met provides essential signals for liver regeneration.

Borowiak M, Garratt AN, Wüstefeld T, Strehle M, Trautwein C, Birchmeier C.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10608-13. Epub 2004 Jul 12.

13.

Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury.

Shin S, Upadhyay N, Greenbaum LE, Kaestner KH.

Gastroenterology. 2015 Jan;148(1):192-202.e3. doi: 10.1053/j.gastro.2014.09.039. Epub 2014 Oct 5.

14.

Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes are involved in mouse liver regeneration.

Tanimizu N, Nishikawa Y, Ichinohe N, Akiyama H, Mitaka T.

J Biol Chem. 2014 Mar 14;289(11):7589-98. doi: 10.1074/jbc.M113.517243. Epub 2014 Jan 30.

15.

Fibroblast growth factor signaling regulates the expansion of A6-expressing hepatocytes in association with AKT-dependent β-catenin activation.

Utley S, James D, Mavila N, Nguyen MV, Vendryes C, Salisbury SM, Phan J, Wang KS.

J Hepatol. 2014 May;60(5):1002-9. doi: 10.1016/j.jhep.2013.12.017. Epub 2013 Dec 21.

16.

Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases.

Son BR, Marquez-Curtis LA, Kucia M, Wysoczynski M, Turner AR, Ratajczak J, Ratajczak MZ, Janowska-Wieczorek A.

Stem Cells. 2006 May;24(5):1254-64. Epub 2006 Jan 12.

17.

Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation.

Yeoh GC, Ernst M, Rose-John S, Akhurst B, Payne C, Long S, Alexander W, Croker B, Grail D, Matthews VB.

Hepatology. 2007 Feb;45(2):486-94.

PMID:
17256754
18.

Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway.

Okano J, Shiota G, Matsumoto K, Yasui S, Kurimasa A, Hisatome I, Steinberg P, Murawaki Y.

Biochem Biophys Res Commun. 2003 Sep 19;309(2):298-304.

PMID:
12951049
19.

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