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Items: 1 to 20 of 112

1.

Linking neurodevelopmental and synaptic theories of mental illness through DISC1.

Brandon NJ, Sawa A.

Nat Rev Neurosci. 2011 Nov 18;12(12):707-22. doi: 10.1038/nrn3120. Review.

2.

Understanding the role of DISC1 in psychiatric disease and during normal development.

Brandon NJ, Millar JK, Korth C, Sive H, Singh KK, Sawa A.

J Neurosci. 2009 Oct 14;29(41):12768-75. doi: 10.1523/JNEUROSCI.3355-09.2009. Review.

3.

DISC1 at 10: connecting psychiatric genetics and neuroscience.

Porteous DJ, Millar JK, Brandon NJ, Sawa A.

Trends Mol Med. 2011 Dec;17(12):699-706. doi: 10.1016/j.molmed.2011.09.002. Epub 2011 Oct 19. Review.

4.

The DISC locus in psychiatric illness.

Chubb JE, Bradshaw NJ, Soares DC, Porteous DJ, Millar JK.

Mol Psychiatry. 2008 Jan;13(1):36-64. Epub 2007 Oct 2. Review.

PMID:
17912248
5.

Disrupted in schizophrenia 1 and synaptic function in the mammalian central nervous system.

Randall AD, Kurihara M, Brandon NJ, Brown JT.

Eur J Neurosci. 2014 Apr;39(7):1068-73. doi: 10.1111/ejn.12500. Review.

6.

DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness.

Millar JK, James R, Brandon NJ, Thomson PA.

Ann Med. 2004;36(5):367-78. Review.

PMID:
15478311
7.

Synaptic dysregulation in a human iPS cell model of mental disorders.

Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, Yoritomo N, Kaibuchi K, Zou J, Christian KM, Cheng L, Ross CA, Margolis RL, Chen G, Kosik KS, Song H, Ming GL.

Nature. 2014 Nov 20;515(7527):414-8. doi: 10.1038/nature13716. Epub 2014 Aug 17.

8.

DISC1: a key lead in studying cortical development and associated brain disorders.

Narayan S, Nakajima K, Sawa A.

Neuroscientist. 2013 Oct;19(5):451-64. doi: 10.1177/1073858412470168. Epub 2013 Jan 8. Review.

9.

Molecular mechanism of schizophrenia with reference to disrupted-in-schizophrenia 1 (DISC1).

Matsuzaki S, Tohyama M.

Neurochem Int. 2007 Jul-Sep;51(2-4):165-72. Epub 2007 Jun 27. Review.

PMID:
17664024
10.

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

Ayhan Y, Abazyan B, Nomura J, Kim R, Ladenheim B, Krasnova IN, Sawa A, Margolis RL, Cadet JL, Mori S, Vogel MW, Ross CA, Pletnikov MV.

Mol Psychiatry. 2011 Mar;16(3):293-306. doi: 10.1038/mp.2009.144. Epub 2010 Jan 5.

11.

The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes.

Hennah W, Porteous D.

PLoS One. 2009;4(3):e4906. doi: 10.1371/journal.pone.0004906. Epub 2009 Mar 20.

12.

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

Pletnikov MV, Ayhan Y, Nikolskaia O, Xu Y, Ovanesov MV, Huang H, Mori S, Moran TH, Ross CA.

Mol Psychiatry. 2008 Feb;13(2):173-86, 115. Epub 2007 Sep 11.

PMID:
17848917
13.

Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.

Hennah W, Thomson P, Peltonen L, Porteous D.

Schizophr Bull. 2006 Jul;32(3):409-16. Epub 2006 May 12. Review.

14.

[Neurodevelopmental disturbance in the pathogenesis of major mental disorders].

Kamiya A, Kitabatake Y, Sawa A.

Brain Nerve. 2008 Apr;60(4):445-52. Review. Japanese.

PMID:
18421986
15.

Utility and validity of DISC1 mouse models in biological psychiatry.

Tomoda T, Sumitomo A, Jaaro-Peled H, Sawa A.

Neuroscience. 2016 May 3;321:99-107. doi: 10.1016/j.neuroscience.2015.12.061. Epub 2016 Jan 6. Review.

PMID:
26768401
16.

Disrupted-In-Schizophrenia-1 (DISC1) interactome and mental disorders: impact of mouse models.

Lipina TV, Roder JC.

Neurosci Biobehav Rev. 2014 Sep;45:271-94. doi: 10.1016/j.neubiorev.2014.07.001. Epub 2014 Jul 9. Review.

PMID:
25016072
17.

Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment.

Schurov IL, Handford EJ, Brandon NJ, Whiting PJ.

Mol Psychiatry. 2004 Dec;9(12):1100-10.

PMID:
15381924
18.

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.

Millar JK, Mackie S, Clapcote SJ, Murdoch H, Pickard BS, Christie S, Muir WJ, Blackwood DH, Roder JC, Houslay MD, Porteous DJ.

J Physiol. 2007 Oct 15;584(Pt 2):401-5. Epub 2007 Sep 6. Review.

19.

DISC1 in schizophrenia: genetic mouse models and human genomic imaging.

Johnstone M, Thomson PA, Hall J, McIntosh AM, Lawrie SM, Porteous DJ.

Schizophr Bull. 2011 Jan;37(1):14-20. doi: 10.1093/schbul/sbq135. Epub 2010 Dec 13. Review.

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