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Items: 1 to 20 of 113

1.

Menin missense mutants encoded by the MEN1 gene that are targeted to the proteasome: restoration of expression and activity by CHIP siRNA.

Canaff L, Vanbellinghen JF, Kanazawa I, Kwak H, Garfield N, Vautour L, Hendy GN.

J Clin Endocrinol Metab. 2012 Feb;97(2):E282-91. doi: 10.1210/jc.2011-0241. Epub 2011 Nov 16.

PMID:
22090276
2.

Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway.

Yaguchi H, Ohkura N, Takahashi M, Nagamura Y, Kitabayashi I, Tsukada T.

Mol Cell Biol. 2004 Aug;24(15):6569-80.

3.

Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms.

Shimazu S, Nagamura Y, Yaguchi H, Ohkura N, Tsukada T.

Cancer Sci. 2011 Nov;102(11):2097-102. doi: 10.1111/j.1349-7006.2011.02055.x. Epub 2011 Sep 1.

4.

Impaired transforming growth factor-β (TGF-β) transcriptional activity and cell proliferation control of a menin in-frame deletion mutant associated with multiple endocrine neoplasia type 1 (MEN1).

Canaff L, Vanbellinghen JF, Kaji H, Goltzman D, Hendy GN.

J Biol Chem. 2012 Mar 9;287(11):8584-97. doi: 10.1074/jbc.M112.341958. Epub 2012 Jan 24.

5.

MEN1 missense mutations impair sensitization to apoptosis induced by wild-type menin in endocrine pancreatic tumor cells.

Bazzi W, Renon M, Vercherat C, Hamze Z, Lacheretz-Bernigaud A, Wang H, Blanc M, Roche C, Calender A, Chayvialle JA, Scoazec JY, Cordier-Bussat M.

Gastroenterology. 2008 Nov;135(5):1698-1709.e2. doi: 10.1053/j.gastro.2008.07.031. Epub 2008 Jul 31.

PMID:
18775714
6.

Application of an intracellular stability test of a novel missense menin mutant to the diagnosis of multiple endocrine neoplasia type 1.

Nagamura Y, Yamazaki M, Shimazu S, Tsukada T, Sakurai A.

Endocr J. 2012;59(12):1093-8. Epub 2012 Aug 9.

7.

Ribozyme-mediated compensatory induction of menin-oncosuppressor function in primary fibroblasts from MEN1 patients.

Luzi E, Marini F, Tognarini I, Carbonell Sala S, Galli G, Falchetti A, Brandi ML.

Cancer Gene Ther. 2010 Nov;17(11):814-25. doi: 10.1038/cgt.2010.39. Epub 2010 Aug 13.

PMID:
20706287
8.

Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma.

Hamze Z, Vercherat C, Bernigaud-Lacheretz A, Bazzi W, Bonnavion R, Lu J, Calender A, Pouponnot C, Bertolino P, Roche C, Stein R, Scoazec JY, Zhang CX, Cordier-Bussat M.

Endocr Relat Cancer. 2013 Oct 24;20(6):833-48. doi: 10.1530/ERC-13-0164. Print 2013 Dec.

9.

Menin promotes the Wnt signaling pathway in pancreatic endocrine cells.

Chen G, A J, Wang M, Farley S, Lee LY, Lee LC, Sawicki MP.

Mol Cancer Res. 2008 Dec;6(12):1894-907. doi: 10.1158/1541-7786.MCR-07-2206.

10.

Threonine-408 Regulates the Stability of Human Pregnane X Receptor through Its Phosphorylation and the CHIP/Chaperone-Autophagy Pathway.

Sugatani J, Noguchi Y, Hattori Y, Yamaguchi M, Yamazaki Y, Ikari A.

Drug Metab Dispos. 2016 Jan;44(1):137-50. doi: 10.1124/dmd.115.066308. Epub 2015 Nov 3.

11.

Caspase 8 and menin expressions are not correlated in human parathyroid tumors.

Yu D, Nagamura Y, Shimazu S, Naito J, Kaji H, Wada S, Honda M, Xue L, Tsukada T.

Endocr J. 2010;57(9):825-32. Epub 2010 Jul 3.

12.

MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases.

Corbo V, Dalai I, Scardoni M, Barbi S, Beghelli S, Bersani S, Albarello L, Doglioni C, Schott C, Capelli P, Chilosi M, Boninsegna L, Becker KF, Falconi M, Scarpa A.

Endocr Relat Cancer. 2010 Aug 16;17(3):771-83. doi: 10.1677/ERC-10-0028. Print 2010 Sep.

13.

Mechanisms of disease: multiple endocrine neoplasia type 1-relation to chromatin modifications and transcription regulation.

Dreijerink KM, Höppener JW, Timmers HM, Lips CJ.

Nat Clin Pract Endocrinol Metab. 2006 Oct;2(10):562-70. Review.

PMID:
17024155
14.

CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.

Kumar P, Ambasta RK, Veereshwarayya V, Rosen KM, Kosik KS, Band H, Mestril R, Patterson C, Querfurth HW.

Hum Mol Genet. 2007 Apr 1;16(7):848-64. Epub 2007 Feb 22.

PMID:
17317785
15.

The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.

Paul I, Ahmed SF, Bhowmik A, Deb S, Ghosh MK.

Oncogene. 2013 Mar 7;32(10):1284-95. doi: 10.1038/onc.2012.144. Epub 2012 Apr 30.

PMID:
22543587
16.

The multiple endocrine neoplasia type 1 gene product, menin, inhibits insulin production in rat insulinoma cells.

Sayo Y, Murao K, Imachi H, Cao WM, Sato M, Dobashi H, Wong NC, Ishida T.

Endocrinology. 2002 Jun;143(6):2437-40.

PMID:
12021209
17.

Functional studies of menin through genetic manipulation of the Men1 homolog in mice.

Balasubramanian D, Scacheri PC.

Adv Exp Med Biol. 2009;668:105-15. Review.

PMID:
20175458
18.

Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.

Gurung B, Feng Z, Iwamoto DV, Thiel A, Jin G, Fan CM, Ng JM, Curran T, Hua X.

Cancer Res. 2013 Apr 15;73(8):2650-8. doi: 10.1158/0008-5472.CAN-12-3158. Epub 2013 Apr 11.

19.

[The role and mechanism of high expression of cyclin B2 in MEN1 insulinoma].

Wu T, Huang XH.

Sheng Li Xue Bao. 2011 Dec 25;63(6):555-64. Chinese.

20.

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