Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 87


Next-generation sequencing of apoptotic DNA breakpoints reveals association with actively transcribed genes and gene translocations.

Fullwood MJ, Lee J, Lin L, Li G, Huss M, Ng P, Sung WK, Shenolikar S.

PLoS One. 2011;6(11):e26054. doi: 10.1371/journal.pone.0026054. Epub 2011 Nov 8.


Characterization of complex chromosomal rearrangements by targeted capture and next-generation sequencing.

Sobreira NL, Gnanakkan V, Walsh M, Marosy B, Wohler E, Thomas G, Hoover-Fong JE, Hamosh A, Wheelan SJ, Valle D.

Genome Res. 2011 Oct;21(10):1720-7. doi: 10.1101/gr.122986.111. Epub 2011 Sep 2.


Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells.

Schwer B, Wei PC, Chang AN, Kao J, Du Z, Meyers RM, Alt FW.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2258-63. doi: 10.1073/pnas.1525564113. Epub 2016 Feb 12.


Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.

Lovett BD, Lo Nigro L, Rappaport EF, Blair IA, Osheroff N, Zheng N, Megonigal MD, Williams WR, Nowell PC, Felix CA.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9802-7. Epub 2001 Aug 7.


Chromatin structural elements and chromosomal translocations in leukemia.

Zhang Y, Rowley JD.

DNA Repair (Amst). 2006 Sep 8;5(9-10):1282-97. Epub 2006 Aug 7. Review.


Next-generation sequencing of translocation renal cell carcinoma reveals novel RNA splicing partners and frequent mutations of chromatin-remodeling genes.

Malouf GG, Su X, Yao H, Gao J, Xiong L, He Q, Compérat E, Couturier J, Molinié V, Escudier B, Camparo P, Doss DJ, Thompson EJ, Khayat D, Wood CG, Yu W, Teh BT, Weinstein J, Tannir NM.

Clin Cancer Res. 2014 Aug 1;20(15):4129-40. doi: 10.1158/1078-0432.CCR-13-3036. Epub 2014 Jun 4.


Methylated actinomycin D, a novel actinomycin D analog induces apoptosis in HepG2 cells through Fas- and mitochondria-mediated pathways.

Chen Y, Liu J, Yuan B, Cao C, Qin S, Cao X, Bian G, Wang Z, Jiang J.

Mol Carcinog. 2013 Dec;52(12):983-96. doi: 10.1002/mc.21943. Epub 2012 Jul 20.


Characterization of human chromosomal material exchange with regard to the chromosome translocations using next-generation sequencing data.

Xu C, Zhang J, Wang YP, Deng HW, Li J.

Genome Biol Evol. 2014 Oct 27;6(11):3015-24. doi: 10.1093/gbe/evu234.


Apoptotic stimuli initiate MLL-AF9 translocations that are transcribed in cells capable of division.

Betti CJ, Villalobos MJ, Diaz MO, Vaughan AT.

Cancer Res. 2003 Mar 15;63(6):1377-81.


Non-random fragmentation patterns in circulating cell-free DNA reflect epigenetic regulation.

Ivanov M, Baranova A, Butler T, Spellman P, Mileyko V.

BMC Genomics. 2015;16 Suppl 13:S1. doi: 10.1186/1471-2164-16-S13-S1. Epub 2015 Dec 16.


Next-generation sequencing applied to flower development: ChIP-Seq.

Graciet E, O'Maoiléidigh DS, Wellmer F.

Methods Mol Biol. 2014;1110:413-29. doi: 10.1007/978-1-4614-9408-9_24.


A workflow to increase verification rate of chromosomal structural rearrangements using high-throughput next-generation sequencing.

Quek K, Nones K, Patch AM, Fink JL, Newell F, Cloonan N, Miller D, Fadlullah MZ, Kassahn K, Christ AN, Bruxner TJ, Manning S, Harliwong I, Idrisoglu S, Nourse C, Nourbakhsh E, Wani S, Steptoe A, Anderson M, Holmes O, Leonard C, Taylor D, Wood S, Xu Q; Australian Pancreatic Cancer Genome Initiative, Wilson P, Biankin AV, Pearson JV, Waddell N, Grimmond SM.

Biotechniques. 2014 Jul 1;57(1):31-8. doi: 10.2144/000114189. eCollection 2014 Jul.


Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.

Zhang Y, Strissel P, Strick R, Chen J, Nucifora G, Le Beau MM, Larson RA, Rowley JD.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3070-5. Epub 2002 Feb 26.


Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements.

Rye M, Sætrom P, Håndstad T, Drabløs F.

BMC Biol. 2011 Nov 24;9:80. doi: 10.1186/1741-7007-9-80.


Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity.

Tewari AK, Yardimci GG, Shibata Y, Sheffield NC, Song L, Taylor BS, Georgiev SG, Coetzee GA, Ohler U, Furey TS, Crawford GE, Febbo PG.

Genome Biol. 2012 Oct 3;13(10):R88. doi: 10.1186/gb-2012-13-10-r88.


The anti-tumor drug bleomycin preferentially cleaves at the transcription start sites of actively transcribed genes in human cells.

Murray V, Chen JK, Galea AM.

Cell Mol Life Sci. 2014 Apr;71(8):1505-12. doi: 10.1007/s00018-013-1456-4. Epub 2013 Aug 28.


Supplemental Content

Support Center