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Items: 1 to 20 of 129

1.

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway.

Nishiyama M, Skoultchi AI, Nakayama KI.

Mol Cell Biol. 2012 Jan;32(2):501-12. doi: 10.1128/MCB.06409-11. Epub 2011 Nov 14.

2.

CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.

Nishiyama M, Oshikawa K, Tsukada Y, Nakagawa T, Iemura S, Natsume T, Fan Y, Kikuchi A, Skoultchi AI, Nakayama KI.

Nat Cell Biol. 2009 Feb;11(2):172-82. doi: 10.1038/ncb1831. Epub 2009 Jan 18.

3.

CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes.

Thompson BA, Tremblay V, Lin G, Bochar DA.

Mol Cell Biol. 2008 Jun;28(12):3894-904. doi: 10.1128/MCB.00322-08. Epub 2008 Mar 31.

4.

A regulatory circuit mediating convergence between Nurr1 transcriptional regulation and Wnt signaling.

Kitagawa H, Ray WJ, Glantschnig H, Nantermet PV, Yu Y, Leu CT, Harada S, Kato S, Freedman LP.

Mol Cell Biol. 2007 Nov;27(21):7486-96. Epub 2007 Aug 20. Retraction in: Mol Cell Biol. 2014 Mar;34(5):917.

5.

Menin promotes the Wnt signaling pathway in pancreatic endocrine cells.

Chen G, A J, Wang M, Farley S, Lee LY, Lee LC, Sawicki MP.

Mol Cancer Res. 2008 Dec;6(12):1894-907. doi: 10.1158/1541-7786.MCR-07-2206.

6.

Human telomerase reverse transcriptase (hTERT) is a novel target of the Wnt/β-catenin pathway in human cancer.

Zhang Y, Toh L, Lau P, Wang X.

J Biol Chem. 2012 Sep 21;287(39):32494-511. Epub 2012 Jul 31.

7.

A DNA binding mutation in estrogen receptor-α leads to suppression of Wnt signaling via β-catenin destabilization in osteoblasts.

Mödder UI, Rudnik V, Liu G, Khosla S, Monroe DG.

J Cell Biochem. 2012 Jul;113(7):2248-55. doi: 10.1002/jcb.24095.

8.

A coactivator role of CARM1 in the dysregulation of β-catenin activity in colorectal cancer cell growth and gene expression.

Ou CY, LaBonte MJ, Manegold PC, So AY, Ianculescu I, Gerke DS, Yamamoto KR, Ladner RD, Kahn M, Kim JH, Stallcup MR.

Mol Cancer Res. 2011 May;9(5):660-70. doi: 10.1158/1541-7786.MCR-10-0223. Epub 2011 Apr 8.

9.

Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.

Zhou C, Zhang Y, Dai J, Zhou M, Liu M, Wang Y, Chen XZ, Tang J.

Sci Rep. 2016 Feb 23;6:22066. doi: 10.1038/srep22066.

10.

CHD8 is an independent prognostic indicator that regulates Wnt/β-catenin signaling and the cell cycle in gastric cancer.

Sawada G, Ueo H, Matsumura T, Uchi R, Ishibashi M, Mima K, Kurashige J, Takahashi Y, Akiyoshi S, Sudo T, Sugimachi K, Doki Y, Mori M, Mimori K.

Oncol Rep. 2013 Sep;30(3):1137-42. doi: 10.3892/or.2013.2597. Epub 2013 Jul 8.

PMID:
23835524
11.

Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.

Lyu J, Jho EH, Lu W.

Cell Res. 2011 Jun;21(6):911-21. doi: 10.1038/cr.2011.47. Epub 2011 Mar 22.

12.

The function of BCL9 in Wnt/beta-catenin signaling and colorectal cancer cells.

de la Roche M, Worm J, Bienz M.

BMC Cancer. 2008 Jul 15;8:199. doi: 10.1186/1471-2407-8-199.

13.

CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells.

Wang P, Mokhtari R, Pedrosa E, Kirschenbaum M, Bayrak C, Zheng D, Lachman HM.

Mol Autism. 2017 Mar 20;8:11. doi: 10.1186/s13229-017-0124-1. eCollection 2017.

14.
15.

Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.

Pfister AS, Tanneberger K, Schambony A, Behrens J.

J Biol Chem. 2012 Jan 13;287(3):1734-41. doi: 10.1074/jbc.M111.308650. Epub 2011 Nov 28.

16.

Phospholipase D1 drives a positive feedback loop to reinforce the Wnt/beta-catenin/TCF signaling axis.

Kang DW, Lee SH, Yoon JW, Park WS, Choi KY, Min do S.

Cancer Res. 2010 May 15;70(10):4233-42. doi: 10.1158/0008-5472.CAN-09-3470. Epub 2010 May 4.

17.

Simplet/Fam53b is required for Wnt signal transduction by regulating β-catenin nuclear localization.

Kizil C, Küchler B, Yan JJ, Özhan G, Moro E, Argenton F, Brand M, Weidinger G, Antos CL.

Development. 2014 Sep;141(18):3529-39. doi: 10.1242/dev.108415.

18.

Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation.

Chen Y, Li Y, Xue J, Gong A, Yu G, Zhou A, Lin K, Zhang S, Zhang N, Gottardi CJ, Huang S.

EMBO J. 2016 Mar 15;35(6):668-84. doi: 10.15252/embj.201592810. Epub 2016 Feb 24.

19.

The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.

Loregger A, Grandl M, Mejías-Luque R, Allgäuer M, Degenhart K, Haselmann V, Oikonomou C, Hatzis P, Janssen KP, Nitsche U, Gradl D, van den Broek O, Destree O, Ulm K, Neumaier M, Kalali B, Jung A, Varela I, Schmid RM, Rad R, Busch DH, Gerhard M.

Sci Signal. 2015 Sep 8;8(393):ra90. doi: 10.1126/scisignal.aac6757.

PMID:
26350900
20.

Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors.

Kim JT, Li J, Jang ER, Gulhati P, Rychahou PG, Napier DL, Wang C, Weiss HL, Lee EY, Anthony L, Townsend CM Jr, Liu C, Evers BM.

Carcinogenesis. 2013 May;34(5):953-61. doi: 10.1093/carcin/bgt018. Epub 2013 Jan 25.

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