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Items: 1 to 20 of 127

1.

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

Kang TW, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L.

Nature. 2011 Nov 9;479(7374):547-51. doi: 10.1038/nature10599.

PMID:
22080947
2.

Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies.

Hoenicke L, Zender L.

Carcinogenesis. 2012 Jun;33(6):1123-6. doi: 10.1093/carcin/bgs124. Epub 2012 Apr 2. Review.

PMID:
22470164
3.

Cancer: final act of senescence.

Serrano M.

Nature. 2011 Nov 23;479(7374):481-2. doi: 10.1038/479481a. No abstract available.

PMID:
22113687
4.

Registered report: senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

Raouf S, Weston C, Yucel N; Reproducibility Project: Cancer Biology.

Elife. 2015 Jan 26;4. doi: 10.7554/eLife.04105.

5.

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.

Tasdemir N, Banito A, Roe JS, Alonso-Curbelo D, Camiolo M, Tschaharganeh DF, Huang CH, Aksoy O, Bolden JE, Chen CC, Fennell M, Thapar V, Chicas A, Vakoc CR, Lowe SW.

Cancer Discov. 2016 Jun;6(6):612-29. doi: 10.1158/2159-8290.CD-16-0217. Epub 2016 Apr 20.

6.

Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer.

Schneider C, Teufel A, Yevsa T, Staib F, Hohmeyer A, Walenda G, Zimmermann HW, Vucur M, Huss S, Gassler N, Wasmuth HE, Lira SA, Zender L, Luedde T, Trautwein C, Tacke F.

Gut. 2012 Dec;61(12):1733-43. doi: 10.1136/gutjnl-2011-301116. Epub 2012 Jan 20.

7.

NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis.

Ma C, Kesarwala AH, Eggert T, Medina-Echeverz J, Kleiner DE, Jin P, Stroncek DF, Terabe M, Kapoor V, ElGindi M, Han M, Thornton AM, Zhang H, Egger M, Luo J, Felsher DW, McVicar DW, Weber A, Heikenwalder M, Greten TF.

Nature. 2016 Mar 10;531(7593):253-7. doi: 10.1038/nature16969. Epub 2016 Mar 2.

8.

Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression.

Eggert T, Wolter K, Ji J, Ma C, Yevsa T, Klotz S, Medina-Echeverz J, Longerich T, Forgues M, Reisinger F, Heikenwalder M, Wang XW, Zender L, Greten TF.

Cancer Cell. 2016 Oct 10;30(4):533-547. doi: 10.1016/j.ccell.2016.09.003.

PMID:
27728804
9.

Induction of anti-tumor immunity by dendritic cells transduced with FAT10 recombinant adenovirus in mice.

Yang Z, Wu D, Zhou D, Jiao F, Yang W, Huan Y.

Cell Immunol. 2015 Jan;293(1):17-21. doi: 10.1016/j.cellimm.2014.11.003. Epub 2014 Nov 11.

PMID:
25461613
10.

Clearance of senescent hepatocytes in a neoplastic-prone microenvironment delays the emergence of hepatocellular carcinoma.

Marongiu F, Serra MP, Sini M, Angius F, Laconi E.

Aging (Albany NY). 2014 Jan;6(1):26-34.

11.

Genome-wide transcriptional reorganization associated with senescence-to-immortality switch during human hepatocellular carcinogenesis.

Yildiz G, Arslan-Ergul A, Bagislar S, Konu O, Yuzugullu H, Gursoy-Yuzugullu O, Ozturk N, Ozen C, Ozdag H, Erdal E, Karademir S, Sagol O, Mizrak D, Bozkaya H, Ilk HG, Ilk O, Bilen B, Cetin-Atalay R, Akar N, Ozturk M.

PLoS One. 2013 May 15;8(5):e64016. doi: 10.1371/journal.pone.0064016. Print 2013.

12.

Oncogene-induced senescence as an initial barrier in lymphoma development.

Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, Schlegelberger B, Stein H, Dörken B, Jenuwein T, Schmitt CA.

Nature. 2005 Aug 4;436(7051):660-5.

13.

Autoimmune hepatic inflammation by vaccination of mice with dendritic cells loaded with well-differentiated hepatocellular carcinoma cells and administration of interleukin-12.

Tamaki S, Homma S, Enomoto Y, Komita H, Zeniya M, Ohno T, Toda G.

Clin Immunol. 2005 Dec;117(3):280-93. Epub 2005 Oct 24.

PMID:
16246626
14.

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration.

Irvine KM, Skoien R, Bokil NJ, Melino M, Thomas GP, Loo D, Gabrielli B, Hill MM, Sweet MJ, Clouston AD, Powell EE.

World J Gastroenterol. 2014 Dec 21;20(47):17851-62. doi: 10.3748/wjg.v20.i47.17851.

15.

Tumour biology: senescence in premalignant tumours.

Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguría A, Zaballos A, Flores JM, Barbacid M, Beach D, Serrano M.

Nature. 2005 Aug 4;436(7051):642.

16.

Liver stem cells: implications for hepatocarcinogenesis.

Alison MR.

Stem Cell Rev. 2005;1(3):253-60. Review.

PMID:
17142862
17.

Autophagy enhances antitumor immune responses induced by irradiated hepatocellular carcinoma cells engineered to express hepatitis B virus X protein.

Yan Y, Liu N, Lu L, Zang CM, Shao B, Li Y, Wen Y, Wei Y, Cheng P.

Oncol Rep. 2013 Aug;30(2):993-9. doi: 10.3892/or.2013.2531. Epub 2013 Jun 10.

PMID:
23754319
18.

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas.

Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, Cordon-Cardo C, Lowe SW.

Nature. 2007 Feb 8;445(7128):656-60. Epub 2007 Jan 24. Erratum in: Nature. 2011 May 26;473(7348):544.

19.

A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes.

Gotzmann J, Fischer AN, Zojer M, Mikula M, Proell V, Huber H, Jechlinger M, Waerner T, Weith A, Beug H, Mikulits W.

Oncogene. 2006 May 25;25(22):3170-85.

PMID:
16607286
20.

Immunosurveillance of senescent cells: the bright side of the senescence program.

Sagiv A, Krizhanovsky V.

Biogerontology. 2013 Dec;14(6):617-28. doi: 10.1007/s10522-013-9473-0. Epub 2013 Oct 10. Review.

PMID:
24114507

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