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Items: 1 to 20 of 102


Contact-dependent T cell activation and T cell stopping require talin1.

Wernimont SA, Wiemer AJ, Bennin DA, Monkley SJ, Ludwig T, Critchley DR, Huttenlocher A.

J Immunol. 2011 Dec 15;187(12):6256-67. doi: 10.4049/jimmunol.1102028. Epub 2011 Nov 9.


Talin1 regulates TCR-mediated LFA-1 function.

Simonson WT, Franco SJ, Huttenlocher A.

J Immunol. 2006 Dec 1;177(11):7707-14.


PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells.

Wernimont SA, Legate KR, Simonson WT, Fassler R, Huttenlocher A.

J Immunol. 2010 Oct 15;185(8):4714-23. doi: 10.4049/jimmunol.1001445. Epub 2010 Sep 20.


F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse.

Comrie WA, Babich A, Burkhardt JK.

J Cell Biol. 2015 Feb 16;208(4):475-91. doi: 10.1083/jcb.201406121. Epub 2015 Feb 9.


Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.

Doherty M, Osborne DG, Browning DL, Parker DC, Wetzel SA.

J Immunol. 2010 Apr 1;184(7):3598-608. doi: 10.4049/jimmunol.0902285. Epub 2010 Mar 5.


CXCL12 Regulates through JAK1 and JAK2 Formation of Productive Immunological Synapses.

Cascio G, Martín-Cófreces NB, Rodríguez-Frade JM, López-Cotarelo P, Criado G, Pablos JL, Rodríguez-Fernández JL, Sánchez-Madrid F, Mellado M.

J Immunol. 2015 Jun 1;194(11):5509-19. doi: 10.4049/jimmunol.1402419. Epub 2015 Apr 27.


Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction.

Tamir A, Eisenbraun MD, Garcia GG, Miller RA.

J Immunol. 2000 Aug 1;165(3):1243-51.


Activation of the ancestral polarity regulator protein kinase C zeta at the immunological synapse drives polarization of Th cell secretory machinery toward APCs.

Bertrand F, Esquerré M, Petit AE, Rodrigues M, Duchez S, Delon J, Valitutti S.

J Immunol. 2010 Sep 1;185(5):2887-94. doi: 10.4049/jimmunol.1000739. Epub 2010 Aug 2.


The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling.

Calvez R, Lafouresse F, De Meester J, Galy A, Valitutti S, Dupré L.

Haematologica. 2011 Oct;96(10):1415-23. doi: 10.3324/haematol.2011.040204. Epub 2011 Jun 9.


LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo.

Kandula S, Abraham C.

J Immunol. 2004 Oct 1;173(7):4443-51.


Talin1 is required for integrin-dependent B lymphocyte homing to lymph nodes and the bone marrow but not for follicular B-cell maturation in the spleen.

Manevich-Mendelson E, Grabovsky V, Feigelson SW, Cinamon G, Gore Y, Goverse G, Monkley SJ, Margalit R, Melamed D, Mebius RE, Critchley DR, Shachar I, Alon R.

Blood. 2010 Dec 23;116(26):5907-18. doi: 10.1182/blood-2010-06-293506. Epub 2010 Oct 5.


Sustained LFA-1 cluster formation in the immune synapse requires the combined activities of L-plastin and calmodulin.

Wabnitz GH, Lohneis P, Kirchgessner H, Jahraus B, Gottwald S, Konstandin M, Klemke M, Samstag Y.

Eur J Immunol. 2010 Sep;40(9):2437-49. doi: 10.1002/eji.201040345.


Imaging of plasmacytoid dendritic cell interactions with T cells.

Mittelbrunn M, Martínez del Hoyo G, López-Bravo M, Martín-Cofreces NB, Scholer A, Hugues S, Fetler L, Amigorena S, Ardavín C, Sánchez-Madrid F.

Blood. 2009 Jan 1;113(1):75-84. doi: 10.1182/blood-2008-02-139865. Epub 2008 Sep 25.


Early and dynamic polarization of T cell membrane rafts and constituents prior to TCR stop signals.

Van Komen JS, Mishra S, Byrum J, Chichili GR, Yaciuk JC, Farris AD, Rodgers W.

J Immunol. 2007 Nov 15;179(10):6845-55.


Reciprocal polarization of T and B cells at the immunological synapse.

Duchez S, Rodrigues M, Bertrand F, Valitutti S.

J Immunol. 2011 Nov 1;187(9):4571-80. doi: 10.4049/jimmunol.1100600. Epub 2011 Sep 19.


Dynamic equilibrium of B7-1 dimers and monomers differentially affects immunological synapse formation and T cell activation in response to TCR/CD28 stimulation.

Bhatia S, Sun K, Almo SC, Nathenson SG, Hodes RJ.

J Immunol. 2010 Feb 15;184(4):1821-8. doi: 10.4049/jimmunol.0902869. Epub 2010 Jan 11.


Imaging the immunological synapse between dendritic cells and T cells.

Markey KA, Gartlan KH, Kuns RD, MacDonald KP, Hill GR.

J Immunol Methods. 2015 Aug;423:40-4. doi: 10.1016/j.jim.2015.04.029. Epub 2015 May 9.


Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells.

Wernimont SA, Simonson WT, Greer PA, Seroogy CM, Huttenlocher A.

PLoS One. 2010 May 7;5(5):e10513. doi: 10.1371/journal.pone.0010513.

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