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Items: 1 to 20 of 105

1.

Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton.

Marat AL, Ioannou MS, McPherson PS.

Mol Biol Cell. 2012 Jan;23(1):163-75. doi: 10.1091/mbc.E11-05-0474. Epub 2011 Nov 9.

2.

The connecdenn family, Rab35 guanine nucleotide exchange factors interfacing with the clathrin machinery.

Marat AL, McPherson PS.

J Biol Chem. 2010 Apr 2;285(14):10627-37. doi: 10.1074/jbc.M109.050930. Epub 2010 Feb 12.

3.

Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors.

Kulasekaran G, Nossova N, Marat AL, Lund I, Cremer C, Ioannou MS, McPherson PS.

J Biol Chem. 2015 Jul 17;290(29):17999-8008. doi: 10.1074/jbc.M115.636712. Epub 2015 Jun 8.

4.

Rab35: GEFs, GAPs and effectors.

Chaineau M, Ioannou MS, McPherson PS.

Traffic. 2013 Nov;14(11):1109-17. doi: 10.1111/tra.12096. Epub 2013 Aug 21. Review.

5.

The Connecdenn DENN domain: a GEF for Rab35 mediating cargo-specific exit from early endosomes.

Allaire PD, Marat AL, Dall'Armi C, Di Paolo G, McPherson PS, Ritter B.

Mol Cell. 2010 Feb 12;37(3):370-82. doi: 10.1016/j.molcel.2009.12.037.

6.

Analysis of connecdenn 1-3 (DENN1A-C) GEF activity for Rab35.

Allaire PD, McPherson PS, Ritter B.

Methods Mol Biol. 2015;1298:217-31. doi: 10.1007/978-1-4939-2569-8_19.

PMID:
25800846
7.

Rab35 controls actin bundling by recruiting fascin as an effector protein.

Zhang J, Fonovic M, Suyama K, Bogyo M, Scott MP.

Science. 2009 Sep 4;325(5945):1250-4. doi: 10.1126/science.1174921.

8.

Rab35 GTPase Triggers Switch-like Recruitment of the Lowe Syndrome Lipid Phosphatase OCRL on Newborn Endosomes.

Cauvin C, Rosendale M, Gupta-Rossi N, Rocancourt M, Larraufie P, Salomon R, Perrais D, Echard A.

Curr Biol. 2016 Jan 11;26(1):120-8. doi: 10.1016/j.cub.2015.11.040. Epub 2015 Dec 24.

9.

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

Yoshimura S, Gerondopoulos A, Linford A, Rigden DJ, Barr FA.

J Cell Biol. 2010 Oct 18;191(2):367-81. doi: 10.1083/jcb.201008051. Epub 2010 Oct 11.

10.

Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate.

Wu X, Bradley MJ, Cai Y, K├╝mmel D, De La Cruz EM, Barr FA, Reinisch KM.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18672-7. doi: 10.1073/pnas.1110415108. Epub 2011 Nov 7.

11.
12.

Connecdenn, a novel DENN domain-containing protein of neuronal clathrin-coated vesicles functioning in synaptic vesicle endocytosis.

Allaire PD, Ritter B, Thomas S, Burman JL, Denisov AY, Legendre-Guillemin V, Harper SQ, Davidson BL, Gehring K, McPherson PS.

J Neurosci. 2006 Dec 20;26(51):13202-12.

13.

The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF.

Banerjee J, Fischer CC, Wedegaertner PB.

Biochemistry. 2009 Aug 25;48(33):8032-43. doi: 10.1021/bi9010013.

14.

Frabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membrane.

Nakanishi H, Takai Y.

J Cell Mol Med. 2008 Aug;12(4):1169-76. doi: 10.1111/j.1582-4934.2008.00345.x. Epub 2008 Apr 9. Review.

15.

Functional characterization of the guanine nucleotide exchange factor (GEF) motif of GIV protein reveals a threshold effect in signaling.

Garcia-Marcos M, Kietrsunthorn PS, Pavlova Y, Adia MA, Ghosh P, Farquhar MG.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1961-6. doi: 10.1073/pnas.1120538109. Epub 2012 Jan 25.

16.

Characterization of RIN3 as a guanine nucleotide exchange factor for the Rab5 subfamily GTPase Rab31.

Kajiho H, Sakurai K, Minoda T, Yoshikawa M, Nakagawa S, Fukushima S, Kontani K, Katada T.

J Biol Chem. 2011 Jul 8;286(27):24364-73. doi: 10.1074/jbc.M110.172445. Epub 2011 May 17.

17.

Genome-wide investigation of the Rab binding activity of RUN domains: development of a novel tool that specifically traps GTP-Rab35.

Fukuda M, Kobayashi H, Ishibashi K, Ohbayashi N.

Cell Struct Funct. 2011;36(2):155-70. Epub 2011 Jul 7.

18.

Trix, a novel Rac guanine-nucleotide exchange factor from Dictyostelium discoideum is an actin-binding protein and accumulates at endosomes.

Strehle A, Schleicher M, Faix J.

Eur J Cell Biol. 2006 Sep;85(9-10):1035-45. Epub 2006 Jun 14.

PMID:
16781009
19.

The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin.

Bellanger JM, Astier C, Sardet C, Ohta Y, Stossel TP, Debant A.

Nat Cell Biol. 2000 Dec;2(12):888-92.

PMID:
11146652
20.

DENN domain proteins: regulators of Rab GTPases.

Marat AL, Dokainish H, McPherson PS.

J Biol Chem. 2011 Apr 22;286(16):13791-800. doi: 10.1074/jbc.R110.217067. Epub 2011 Feb 17. Review.

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