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Items: 1 to 20 of 347

1.
2.

High-throughput cytochrome P450 inhibition assays using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry.

Wu J, Hughes CS, Picard P, Letarte S, Gaudreault M, Lévesque JF, Nicoll-Griffith DA, Bateman KP.

Anal Chem. 2007 Jun 15;79(12):4657-65. Epub 2007 May 12.

PMID:
17497828
3.

Laser diode thermal desorption-positive mode atmospheric pressure chemical ionization tandem mass spectrometry for the ultra-fast quantification of a pharmaceutical compound in human plasma.

Heudi O, Barteau S, Picard P, Tremblay P, Picard F, Kretz O.

J Pharm Biomed Anal. 2011 Apr 5;54(5):1088-95. doi: 10.1016/j.jpba.2010.11.025. Epub 2010 Nov 26.

PMID:
21156343
4.
5.

Ultra-fast cyclosporin A quantitation in whole blood by Laser Diode Thermal Desorption-tandem mass spectrometry; comparison with High Performance Liquid Chromatography-tandem mass spectrometry.

Jourdil JF, Picard P, Meunier C, Auger S, Stanke-Labesque F.

Anal Chim Acta. 2013 Dec 17;805:80-6. doi: 10.1016/j.aca.2013.10.051. Epub 2013 Nov 6.

PMID:
24296146
6.

Coupling Laser Diode Thermal Desorption with Acoustic Sample Deposition to Improve Throughput of Mass Spectrometry-Based Screening.

Haarhoff Z, Wagner A, Picard P, Drexler DM, Zvyaga T, Shou W.

J Biomol Screen. 2016 Feb;21(2):165-75. doi: 10.1177/1087057115607184. Epub 2015 Sep 29.

PMID:
26420787
7.
8.

An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.

Otten JN, Hingorani GP, Hartley DP, Kragerud SD, Franklin RB.

Drug Metab Lett. 2011 Jan;5(1):17-24.

PMID:
21198441
9.

Development of a high-throughput online solid-phase extraction/tandem mass spectrometry method for cytochrome P450 inhibition screening.

Lim KB, Ozbal CC, Kassel DB.

J Biomol Screen. 2010 Apr;15(4):447-52. doi: 10.1177/1087057110362581. Epub 2010 Mar 5.

PMID:
20208033
10.

Laser diode thermal desorption atmospheric pressure chemical ionization tandem mass spectrometry applied for the ultra-fast quantitative analysis of BKM120 in human plasma.

Lanshoeft C, Heudi O, Leuthold LA, Schlotterbeck G, Elbast W, Picard F, Kretz O.

Anal Bioanal Chem. 2014 Sep;406(22):5413-23. doi: 10.1007/s00216-014-7966-6. Epub 2014 Jun 24.

PMID:
24958346
11.

Extending matrix-assisted laser desorption/ionization triple quadrupole mass spectrometry enzyme screening assays to targets with small molecule substrates.

Rathore R, Corr JJ, Lebre DT, Seibel WL, Greis KD.

Rapid Commun Mass Spectrom. 2009 Oct 30;23(20):3293-300. doi: 10.1002/rcm.4248.

PMID:
19757451
12.

Reliable high-throughput method for inhibition assay of 8 cytochrome P450 isoforms using cocktail of probe substrates and stable isotope-labeled internal standards.

Kozakai K, Yamada Y, Oshikata M, Kawase T, Suzuki E, Haramaki Y, Taniguchi H.

Drug Metab Pharmacokinet. 2012;27(5):520-9. Epub 2012 Apr 10.

13.

Evaluation of laser diode thermal desorption-tandem mass spectrometry (LDTD-MS-MS) in forensic toxicology.

Bynum ND, Moore KN, Grabenauer M.

J Anal Toxicol. 2014 Oct;38(8):528-35. doi: 10.1093/jat/bku084.

PMID:
25217542
14.

Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS--a high throughput approach to evaluate drug-drug interactions.

Zhang W, Han F, Guo P, Zhao H, Lin ZJ, Huang MQ, Bertelsen K, Weng N.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 1;878(15-16):1169-77. doi: 10.1016/j.jchromb.2010.03.026. Epub 2010 Mar 23.

PMID:
20378422
17.

MALDI-TOF MS as a label-free approach to rapid inhibitor screening.

Greis KD, Zhou S, Burt TM, Carr AN, Dolan E, Easwaran V, Evdokimov A, Kawamoto R, Roesgen J, Davis GF.

J Am Soc Mass Spectrom. 2006 Jun;17(6):815-22. Epub 2006 Apr 17.

18.

Ultra-fast analysis of anatoxin-A using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry: validation and resolution from phenylalanine.

Lemoine P, Roy-Lachapelle A, Prévost M, Tremblay P, Solliec M, Sauvé S.

Toxicon. 2013 Jan;61:165-74. doi: 10.1016/j.toxicon.2012.10.021. Epub 2012 Nov 14.

PMID:
23159398
19.

Mass spectrometric techniques for label-free high-throughput screening in drug discovery.

Roddy TP, Horvath CR, Stout SJ, Kenney KL, Ho PI, Zhang JH, Vickers C, Kaushik V, Hubbard B, Wang YK.

Anal Chem. 2007 Nov 1;79(21):8207-13. Epub 2007 Sep 29.

PMID:
17902631
20.

Evaluation of a high-throughput online solid phase extraction-tandem mass spectrometry system for in vivo bioanalytical studies.

Jian W, Romm MV, Edom RW, Miller VP, LaMarr WA, Weng N.

Anal Chem. 2011 Nov 1;83(21):8259-66. doi: 10.1021/ac202017c. Epub 2011 Oct 6.

PMID:
21936562

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