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Items: 1 to 20 of 103

1.

Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity.

Ferrari E, Maywood ES, Restani L, Caleo M, Pirazzini M, Rossetto O, Hastings MH, Niranjan D, Schiavo G, Davletov B.

Toxins (Basel). 2011 Apr;3(4):345-55. doi: 10.3390/toxins3040345. Epub 2011 Mar 24.

2.

Long-distance retrograde effects of botulinum neurotoxin A.

Antonucci F, Rossi C, Gianfranceschi L, Rossetto O, Caleo M.

J Neurosci. 2008 Apr 2;28(14):3689-96. doi: 10.1523/JNEUROSCI.0375-08.2008.

3.

Control of autophagosome axonal retrograde flux by presynaptic activity unveiled using botulinum neurotoxin type a.

Wang T, Martin S, Papadopulos A, Harper CB, Mavlyutov TA, Niranjan D, Glass NR, Cooper-White JJ, Sibarita JB, Choquet D, Davletov B, Meunier FA.

J Neurosci. 2015 Apr 15;35(15):6179-94. doi: 10.1523/JNEUROSCI.3757-14.2015.

4.

A dileucine in the protease of botulinum toxin A underlies its long-lived neuroparalysis: transfer of longevity to a novel potential therapeutic.

Wang J, Zurawski TH, Meng J, Lawrence G, Olango WM, Finn DP, Wheeler L, Dolly JO.

J Biol Chem. 2011 Feb 25;286(8):6375-85. doi: 10.1074/jbc.M110.181784. Epub 2010 Dec 7.

5.

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.

Zanetti G, Sikorra S, Rummel A, Krez N, Duregotti E, Negro S, Henke T, Rossetto O, Binz T, Pirazzini M.

PLoS Pathog. 2017 Aug 11;13(8):e1006567. doi: 10.1371/journal.ppat.1006567. eCollection 2017 Aug.

6.

Targeting botulinum neurotoxin persistence by the ubiquitin-proteasome system.

Tsai YC, Maditz R, Kuo CL, Fishman PS, Shoemaker CB, Oyler GA, Weissman AM.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16554-9. doi: 10.1073/pnas.1008302107. Epub 2010 Sep 7.

7.

Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.

Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.

Toxicon. 2013 Dec 1;75:108-21. doi: 10.1016/j.toxicon.2013.06.010. Epub 2013 Jun 29.

PMID:
23817019
8.

Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay.

Fernández-Salas E, Wang J, Molina Y, Nelson JB, Jacky BP, Aoki KR.

PLoS One. 2012;7(11):e49516. doi: 10.1371/journal.pone.0049516. Epub 2012 Nov 21.

9.

Uptake of botulinum neurotoxin into cultured neurons.

Keller JE, Cai F, Neale EA.

Biochemistry. 2004 Jan 20;43(2):526-32.

PMID:
14717608
10.

Mastoparan-7 rescues botulinum toxin-A poisoned neurons in a mouse spinal cord cell culture model.

Zhang P, Ray R, Singh BR, Ray P.

Toxicon. 2013 Dec 15;76:37-43. doi: 10.1016/j.toxicon.2013.09.002. Epub 2013 Sep 15.

11.

A protein chip membrane-capture assay for botulinum neurotoxin activity.

Marconi S, Ferracci G, Berthomieu M, Kozaki S, Miquelis R, Boucraut J, Seagar M, Lévêque C.

Toxicol Appl Pharmacol. 2008 Dec 15;233(3):439-46. doi: 10.1016/j.taap.2008.09.005. Epub 2008 Sep 19.

PMID:
18845174
12.

Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons.

Restani L, Giribaldi F, Manich M, Bercsenyi K, Menendez G, Rossetto O, Caleo M, Schiavo G.

PLoS Pathog. 2012 Dec;8(12):e1003087. doi: 10.1371/journal.ppat.1003087. Epub 2012 Dec 27.

13.

Therapeutic effectiveness of botulinum neurotoxin A: potent blockade of autonomic transmission by targeted cleavage of only the pertinent SNAP-25.

Lawrence GW, Ovsepian SV, Wang J, Aoki KR, Dolly JO.

Neuropharmacology. 2013 Jul;70:287-95. doi: 10.1016/j.neuropharm.2013.02.012. Epub 2013 Feb 26.

PMID:
23485402
14.

Botulinum neurotoxin A impairs neurotransmission following retrograde transynaptic transport.

Restani L, Novelli E, Bottari D, Leone P, Barone I, Galli-Resta L, Strettoi E, Caleo M.

Traffic. 2012 Aug;13(8):1083-9. doi: 10.1111/j.1600-0854.2012.01369.x. Epub 2012 May 9.

15.

Alpha-latrotoxin rescues SNAP-25 from BoNT/A-mediated proteolysis in embryonic stem cell-derived neurons.

Mesngon M, McNutt P.

Toxins (Basel). 2011 May;3(5):489-503. doi: 10.3390/toxins3050489. Epub 2011 May 13.

16.

Longer-acting and highly potent chimaeric inhibitors of excessive exocytosis created with domains from botulinum neurotoxin A and B.

Wang J, Zurawski TH, Bodeker MO, Meng J, Boddul S, Aoki KR, Dolly JO.

Biochem J. 2012 May 15;444(1):59-67. doi: 10.1042/BJ20120100.

PMID:
22360156
17.

Type A botulinum neurotoxin complex proteins differentially modulate host response of neuronal cells.

Wang L, Sun Y, Yang W, Lindo P, Singh BR.

Toxicon. 2014 May;82:52-60. doi: 10.1016/j.toxicon.2014.02.004. Epub 2014 Feb 21.

18.

Evidence for anterograde transport and transcytosis of botulinum neurotoxin A (BoNT/A).

Restani L, Antonucci F, Gianfranceschi L, Rossi C, Rossetto O, Caleo M.

J Neurosci. 2011 Nov 2;31(44):15650-9. doi: 10.1523/JNEUROSCI.2618-11.2011.

19.

Neuronal targeting, internalization, and biological activity of a recombinant atoxic derivative of botulinum neurotoxin A.

Pellett S, Tepp WH, Stanker LH, Band PA, Johnson EA, Ichtchenko K.

Biochem Biophys Res Commun. 2011 Feb 25;405(4):673-7. doi: 10.1016/j.bbrc.2011.01.093. Epub 2011 Feb 1.

20.

Botulinum neurotoxin type A: Actions beyond SNAP-25?

Matak I, Lacković Z.

Toxicology. 2015 Sep 1;335:79-84. doi: 10.1016/j.tox.2015.07.003. Epub 2015 Jul 10. Review.

PMID:
26169827

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