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Items: 1 to 20 of 107

1.

Silencing disease genes in the laboratory and the clinic.

Watts JK, Corey DR.

J Pathol. 2012 Jan;226(2):365-79. doi: 10.1002/path.2993. Epub 2011 Nov 9. Review.

2.

RNA-targeted therapeutics in cancer clinical trials: Current status and future directions.

Barata P, Sood AK, Hong DS.

Cancer Treat Rev. 2016 Nov;50:35-47. doi: 10.1016/j.ctrv.2016.08.004. Epub 2016 Aug 28. Review.

PMID:
27612280
3.

Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies.

Bhindi R, Fahmy RG, Lowe HC, Chesterman CN, Dass CR, Cairns MJ, Saravolac EG, Sun LQ, Khachigian LM.

Am J Pathol. 2007 Oct;171(4):1079-88. Epub 2007 Aug 23. Review.

4.

Conjugates of oligonucleotides and analogues with cell penetrating peptides as gene silencing agents.

Zatsepin TS, Turner JJ, Oretskaya TS, Gait MJ.

Curr Pharm Des. 2005;11(28):3639-54. Review.

PMID:
16305500
5.

Modulation of gene expression by antisense and antigene oligodeoxynucleotides and small interfering RNA.

Mahato RI, Cheng K, Guntaka RV.

Expert Opin Drug Deliv. 2005 Jan;2(1):3-28. Review.

PMID:
16296732
6.

RNA interference in mammalian cell systems.

Lochmatter D, Mullis PE.

Horm Res Paediatr. 2011;75(1):63-9. doi: 10.1159/000322817. Epub 2011 Jan 17. Review.

PMID:
21252559
7.

Designing chemically modified oligonucleotides for targeted gene silencing.

Deleavey GF, Damha MJ.

Chem Biol. 2012 Aug 24;19(8):937-54. doi: 10.1016/j.chembiol.2012.07.011. Review.

8.

Nucleic-acid therapeutics: basic principles and recent applications.

Opalinska JB, Gewirtz AM.

Nat Rev Drug Discov. 2002 Jul;1(7):503-14. Review.

PMID:
12120257
9.

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application.

Jackson AL, Linsley PS.

Nat Rev Drug Discov. 2010 Jan;9(1):57-67. doi: 10.1038/nrd3010. Review.

PMID:
20043028
10.

Therapeutic face of RNAi: in vivo challenges.

Borna H, Imani S, Iman M, Azimzadeh Jamalkandi S.

Expert Opin Biol Ther. 2015 Feb;15(2):269-85. doi: 10.1517/14712598.2015.983070. Epub 2014 Nov 15. Review.

PMID:
25399911
11.

Antisense, RNAi, and gene silencing strategies for therapy: mission possible or impossible?

Rayburn ER, Zhang R.

Drug Discov Today. 2008 Jun;13(11-12):513-21. doi: 10.1016/j.drudis.2008.03.014. Epub 2008 May 3. Review.

12.

Nucleic acid modulation of gene expression: approaches for nucleic acid therapeutics against cancer.

Nakata Y, Kim TK, Shetzline S, Gewirtz AM.

Crit Rev Eukaryot Gene Expr. 2005;15(2):163-82. Review.

PMID:
16022634
13.

[Gene silencing approaches for the treatment of Huntington's disease].

Merienne N, D├ęglon N.

Med Sci (Paris). 2015 Feb;31(2):159-67. doi: 10.1051/medsci/20153102012. Epub 2015 Mar 4. Review. French.

14.

[Recent progress and prospect in oligonucleotide therapeutics].

Yoshioka K, Kuwahara H, Nishina K, Nagata T, Yokota T.

Nihon Rinsho. 2015 Jun;73(6):1057-65. Review. Japanese.

PMID:
26065142
15.

Is there a future for cell-penetrating peptides in oligonucleotide delivery?

Lee SH, Castagner B, Leroux JC.

Eur J Pharm Biopharm. 2013 Sep;85(1):5-11. doi: 10.1016/j.ejpb.2013.03.021. Review.

PMID:
23958313
16.

Progress in the development of nucleic acid therapeutics for cancer.

Kalota A, Shetzline SE, Gewirtz AM.

Cancer Biol Ther. 2004 Jan;3(1):4-12. Epub 2004 Jan 18. Review.

PMID:
14726654
17.

Antisense oligonucleotides: the state of the art.

Aboul-Fadl T.

Curr Med Chem. 2005;12(19):2193-214. Review.

PMID:
16178780
18.

Oncogene-targeted antisense oligonucleotides for the treatment of Ewing sarcoma.

Maksimenko A, Malvy C.

Expert Opin Ther Targets. 2005 Aug;9(4):825-30. Review.

PMID:
16083345
19.

Nucleic acid therapeutics: a work in progress.

Opalinska JB, Gewirtz AM.

Curr Opin Investig Drugs. 2002 Jun;3(6):928-33. Review. No abstract available.

PMID:
12137416
20.

Liver as a target for oligonucleotide therapeutics.

Sehgal A, Vaishnaw A, Fitzgerald K.

J Hepatol. 2013 Dec;59(6):1354-9. doi: 10.1016/j.jhep.2013.05.045. Epub 2013 Jun 12.

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