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Items: 1 to 20 of 128

1.

Identical gene regulation patterns of T3 and selective thyroid hormone receptor modulator GC-1.

Yuan C, Lin JZ, Sieglaff DH, Ayers SD, Denoto-Reynolds F, Baxter JD, Webb P.

Endocrinology. 2012 Jan;153(1):501-11. doi: 10.1210/en.2011-1325. Epub 2011 Nov 8.

2.

Gene specific actions of thyroid hormone receptor subtypes.

Lin JZ, Sieglaff DH, Yuan C, Su J, Arumanayagam AS, Firouzbakht S, Cantu Pompa JJ, Reynolds FD, Zhou X, Cvoro A, Webb P.

PLoS One. 2013;8(1):e52407. doi: 10.1371/journal.pone.0052407. Epub 2013 Jan 3.

3.

Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.

Johansson L, Rudling M, Scanlan TS, Lundåsen T, Webb P, Baxter J, Angelin B, Parini P.

Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10297-302. Epub 2005 Jul 8.

4.

Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation.

Liu YY, Kogai T, Schultz JJ, Mody K, Brent GA.

J Biol Chem. 2012 Oct 19;287(43):36499-508. doi: 10.1074/jbc.M112.344317. Epub 2012 Aug 28.

5.

The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity.

Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH.

Endocrinology. 2000 Sep;141(9):3057-64.

PMID:
10965874
6.

Thyroid Hormone Receptor α Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury.

Milanesi A, Lee JW, Kim NH, Liu YY, Yang A, Sedrakyan S, Kahng A, Cervantes V, Tripuraneni N, Cheng SY, Perin L, Brent GA.

Endocrinology. 2016 Jan;157(1):4-15. doi: 10.1210/en.2015-1443. Epub 2015 Oct 9.

7.

Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.

Ye L, Li YL, Mellström K, Mellin C, Bladh LG, Koehler K, Garg N, Garcia Collazo AM, Litten C, Husman B, Persson K, Ljunggren J, Grover G, Sleph PG, George R, Malm J.

J Med Chem. 2003 Apr 24;46(9):1580-8.

PMID:
12699376
8.

Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice.

Gullberg H, Rudling M, Saltó C, Forrest D, Angelin B, Vennström B.

Mol Endocrinol. 2002 Aug;16(8):1767-77.

PMID:
12145333
9.

In vivo activity of the thyroid hormone receptor beta- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain.

Grijota-Martínez C, Samarut E, Scanlan TS, Morte B, Bernal J.

Endocrinology. 2011 Mar;152(3):1136-42. doi: 10.1210/en.2010-0813. Epub 2011 Jan 14.

10.

Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary.

Sadow PM, Koo E, Chassande O, Gauthier K, Samarut J, Xu J, O'Malley BW, Seo H, Murata Y, Weiss RE.

Mol Endocrinol. 2003 May;17(5):882-94. Epub 2003 Feb 6.

PMID:
12576486
11.

Marked potentiation of the dominant negative action of a mutant thyroid hormone receptor beta in mice by the ablation of one wild-type beta allele.

Suzuki H, Zhang XY, Forrest D, Willingham MC, Cheng SY.

Mol Endocrinol. 2003 May;17(5):895-907. Epub 2003 Feb 6.

PMID:
12576488
12.

Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha.

Macchia PE, Takeuchi Y, Kawai T, Cua K, Gauthier K, Chassande O, Seo H, Hayashi Y, Samarut J, Murata Y, Weiss RE, Refetoff S.

Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):349-54.

13.

Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor.

Zhang XY, Kaneshige M, Kamiya Y, Kaneshige K, McPhie P, Cheng SY.

Mol Endocrinol. 2002 Sep;16(9):2077-92.

PMID:
12198244
14.

Thyroid hormone receptor regulates most genes independently of fibroblast growth factor 21 in liver.

Zhang A, Sieglaff DH, York JP, Suh JH, Ayers SD, Winnier GE, Kharitonenkov A, Pin C, Zhang P, Webb P, Xia X.

J Endocrinol. 2015 Mar;224(3):289-301. doi: 10.1530/JOE-14-0440. Epub 2014 Dec 11.

15.

Differential effects of triiodothyronine and the thyroid hormone receptor beta-specific agonist GC-1 on thyroid hormone target genes in the b ain.

Manzano J, Morte B, Scanlan TS, Bernal J.

Endocrinology. 2003 Dec;144(12):5480-7. Epub 2003 Aug 21.

PMID:
12959999
16.

Selective modulation of thyroid hormone receptor action.

Baxter JD, Dillmann WH, West BL, Huber R, Furlow JD, Fletterick RJ, Webb P, Apriletti JW, Scanlan TS.

J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):31-42. Review.

PMID:
11384861
17.

Thyroid hormone receptor alpha plays an essential role in the normalisation of adult-onset hypothyroidism-related hypoexpression of synaptic plasticity target genes in striatum.

Vallortigara J, Chassande O, Higueret P, Enderlin V.

J Neuroendocrinol. 2009 Jan;21(1):49-56. doi: 10.1111/j.1365-2826.2008.01802.x.

PMID:
19094093
18.

Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine.

Grover GJ, Egan DM, Sleph PG, Beehler BC, Chiellini G, Nguyen NH, Baxter JD, Scanlan TS.

Endocrinology. 2004 Apr;145(4):1656-61. Epub 2003 Dec 30.

PMID:
14701670
19.

Gaining ligand selectivity in thyroid hormone receptors via entropy.

Martínez L, Nascimento AS, Nunes FM, Phillips K, Aparicio R, Dias SM, Figueira AC, Lin JH, Nguyen P, Apriletti JW, Neves FA, Baxter JD, Webb P, Skaf MS, Polikarpov I.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20717-22. doi: 10.1073/pnas.0911024106. Epub 2009 Nov 19.

20.

Liver glutathione S-transferase expression is decreased by 3,5,3-triiodothyronine in hypothyroid but not in euthyroid mice.

Faustino LC, Pires RM, Lima AC, Cordeiro A, Souza LL, Ortiga-Carvalho TM.

Exp Physiol. 2011 Aug;96(8):790-800. doi: 10.1113/expphysiol.2011.058172. Epub 2011 May 6.

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