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Items: 1 to 20 of 248

1.

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.

Kriks S, Shim JW, Piao J, Ganat YM, Wakeman DR, Xie Z, Carrillo-Reid L, Auyeung G, Antonacci C, Buch A, Yang L, Beal MF, Surmeier DJ, Kordower JH, Tabar V, Studer L.

Nature. 2011 Nov 6;480(7378):547-51. doi: 10.1038/nature10648.

2.

Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons.

Sundberg M, Bogetofte H, Lawson T, Jansson J, Smith G, Astradsson A, Moore M, Osborn T, Cooper O, Spealman R, Hallett P, Isacson O.

Stem Cells. 2013 Aug;31(8):1548-62. doi: 10.1002/stem.1415.

3.

Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.

Cooper O, Hargus G, Deleidi M, Blak A, Osborn T, Marlow E, Lee K, Levy A, Perez-Torres E, Yow A, Isacson O.

Mol Cell Neurosci. 2010 Nov;45(3):258-66. doi: 10.1016/j.mcn.2010.06.017. Epub 2010 Jul 24.

4.

In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons.

Park CH, Minn YK, Lee JY, Choi DH, Chang MY, Shim JW, Ko JY, Koh HC, Kang MJ, Kang JS, Rhie DJ, Lee YS, Son H, Moon SY, Kim KS, Lee SH.

J Neurochem. 2005 Mar;92(5):1265-76.

5.

Embryonic stem cell-derived Pitx3-enhanced green fluorescent protein midbrain dopamine neurons survive enrichment by fluorescence-activated cell sorting and function in an animal model of Parkinson's disease.

Hedlund E, Pruszak J, Lardaro T, Ludwig W, Viñuela A, Kim KS, Isacson O.

Stem Cells. 2008 Jun;26(6):1526-36. doi: 10.1634/stemcells.2007-0996. Epub 2008 Apr 3.

6.

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment.

Ganat YM, Calder EL, Kriks S, Nelander J, Tu EY, Jia F, Battista D, Harrison N, Parmar M, Tomishima MJ, Rutishauser U, Studer L.

J Clin Invest. 2012 Aug;122(8):2928-39. doi: 10.1172/JCI58767. Epub 2012 Jul 2.

7.

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice.

Parish CL, Castelo-Branco G, Rawal N, Tonnesen J, Sorensen AT, Salto C, Kokaia M, Lindvall O, Arenas E.

J Clin Invest. 2008 Jan;118(1):149-60.

8.

Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopamine neurons mediated by the Lmx1a and neurturin in vitro: potential therapeutic application for Parkinson's disease in a rhesus monkey model.

Yan M, Sun M, Zhou Y, Wang W, He Z, Tang D, Lu S, Wang X, Li S, Wang W, Li H.

PLoS One. 2013 May 28;8(5):e64000. doi: 10.1371/journal.pone.0064000. Print 2013.

9.
10.

Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation.

Doi D, Samata B, Katsukawa M, Kikuchi T, Morizane A, Ono Y, Sekiguchi K, Nakagawa M, Parmar M, Takahashi J.

Stem Cell Reports. 2014 Mar 6;2(3):337-50. doi: 10.1016/j.stemcr.2014.01.013. eCollection 2014 Mar 11.

11.

Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells.

Sánchez-Danés A, Consiglio A, Richaud Y, Rodríguez-Pizà I, Dehay B, Edel M, Bové J, Memo M, Vila M, Raya A, Izpisua Belmonte JC.

Hum Gene Ther. 2012 Jan;23(1):56-69. doi: 10.1089/hum.2011.054. Epub 2011 Nov 17.

12.

Comparative study of efficacy of dopaminergic neuron differentiation between embryonic stem cell and protein-based induced pluripotent stem cell.

Kwon YW, Chung YJ, Kim J, Lee HJ, Park J, Roh TY, Cho HJ, Yoon CH, Koo BK, Kim HS.

PLoS One. 2014 Jan 22;9(1):e85736. doi: 10.1371/journal.pone.0085736. eCollection 2014.

13.

Docosahexaenoic acid promotes dopaminergic differentiation in induced pluripotent stem cells and inhibits teratoma formation in rats with Parkinson-like pathology.

Chang YL, Chen SJ, Kao CL, Hung SC, Ding DC, Yu CC, Chen YJ, Ku HH, Lin CP, Lee KH, Chen YC, Wang JJ, Hsu CC, Chen LK, Li HY, Chiou SH.

Cell Transplant. 2012;21(1):313-32. doi: 10.3727/096368911X580572. Epub 2011 Jun 7.

PMID:
21669041
14.

Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons.

Sagal J, Zhan X, Xu J, Tilghman J, Karuppagounder SS, Chen L, Dawson VL, Dawson TM, Laterra J, Ying M.

Stem Cells Transl Med. 2014 Aug;3(8):888-98. doi: 10.5966/sctm.2013-0213. Epub 2014 Jun 5.

15.

Generation of dopamine neurons from embryonic stem cells in the presence of the neuralizing activity of bone marrow stromal cells derived from adult mice.

Shintani A, Nakao N, Kakishita K, Itakura T.

J Neurosci Res. 2008 Oct;86(13):2829-38. doi: 10.1002/jnr.21748.

PMID:
18561325
16.

Co-transplantation of GDNF-overexpressing neural stem cells and fetal dopaminergic neurons mitigates motor symptoms in a rat model of Parkinson's disease.

Deng X, Liang Y, Lu H, Yang Z, Liu R, Wang J, Song X, Long J, Li Y, Lei D, Feng Z.

PLoS One. 2013 Dec 3;8(12):e80880. doi: 10.1371/journal.pone.0080880. eCollection 2013.

17.

Expression of early developmental markers predicts the efficiency of embryonic stem cell differentiation into midbrain dopaminergic neurons.

Salti A, Nat R, Neto S, Puschban Z, Wenning G, Dechant G.

Stem Cells Dev. 2013 Feb 1;22(3):397-411. doi: 10.1089/scd.2012.0238. Epub 2012 Sep 20.

18.

Brn4 and TH synergistically promote the differentiation of neural stem cells into dopaminergic neurons.

Tan X, Zhang L, Zhu H, Qin J, Tian M, Dong C, Li H, Jin G.

Neurosci Lett. 2014 Jun 13;571:23-8. doi: 10.1016/j.neulet.2014.04.019. Epub 2014 Apr 24.

PMID:
24769320
19.

Stem cell grafting improves both motor and cognitive impairments in a genetic model of Parkinson's disease, the aphakia (ak) mouse.

Moon J, Lee HS, Kang JM, Park J, Leung A, Hong S, Chung S, Kim KS.

Cell Transplant. 2013;22(7):1263-79. doi: 10.3727/096368912X657242. Epub 2012 Oct 2.

20.

Specification of midbrain dopamine neurons from primate pluripotent stem cells.

Xi J, Liu Y, Liu H, Chen H, Emborg ME, Zhang SC.

Stem Cells. 2012 Aug;30(8):1655-63. doi: 10.1002/stem.1152.

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