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Items: 1 to 20 of 152

1.

Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts.

Luchsinger LL, Patenaude CA, Smith BD, Layne MD.

J Biol Chem. 2011 Dec 23;286(51):44116-25. doi: 10.1074/jbc.M111.276931. Epub 2011 Nov 2.

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Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors.

Lockman K, Hinson JS, Medlin MD, Morris D, Taylor JM, Mack CP.

J Biol Chem. 2004 Oct 8;279(41):42422-30. Epub 2004 Aug 3.

4.

The Purα/Purβ single-strand DNA-binding proteins attenuate smooth-muscle actin gene transactivation in myofibroblasts.

Hariharan S, Kelm RJ Jr, Strauch AR.

J Cell Physiol. 2014 Sep;229(9):1256-71. doi: 10.1002/jcp.24564.

PMID:
24446247
5.

Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.

Haak AJ, Tsou PS, Amin MA, Ruth JH, Campbell P, Fox DA, Khanna D, Larsen SD, Neubig RR.

J Pharmacol Exp Ther. 2014 Jun;349(3):480-6. doi: 10.1124/jpet.114.213520. Epub 2014 Apr 4.

6.

Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.

Small EM, Thatcher JE, Sutherland LB, Kinoshita H, Gerard RD, Richardson JA, Dimaio JM, Sadek H, Kuwahara K, Olson EN.

Circ Res. 2010 Jul 23;107(2):294-304. doi: 10.1161/CIRCRESAHA.110.223172. Epub 2010 Jun 17.

7.

Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors.

Hinson JS, Medlin MD, Lockman K, Taylor JM, Mack CP.

Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H1170-80. Epub 2006 Sep 22.

8.

Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts.

Johnson LA, Rodansky ES, Haak AJ, Larsen SD, Neubig RR, Higgins PD.

Inflamm Bowel Dis. 2014 Jan;20(1):154-65. doi: 10.1097/01.MIB.0000437615.98881.31.

9.

β-catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial-myofibroblast transition.

Charbonney E, Speight P, Masszi A, Nakano H, Kapus A.

Mol Biol Cell. 2011 Dec;22(23):4472-85. doi: 10.1091/mbc.E11-04-0335. Epub 2011 Sep 30.

10.

The role of RhoA and cytoskeleton in myofibroblast transformation in hyperoxic lung fibrosis.

Ni J, Dong Z, Han W, Kondrikov D, Su Y.

Free Radic Biol Med. 2013 Aug;61:26-39. doi: 10.1016/j.freeradbiomed.2013.03.012. Epub 2013 Mar 18.

11.

Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.

Sisson TH, Ajayi IO, Subbotina N, Dodi AE, Rodansky ES, Chibucos LN, Kim KK, Keshamouni VG, White ES, Zhou Y, Higgins PD, Larsen SD, Neubig RR, Horowitz JC.

Am J Pathol. 2015 Apr;185(4):969-86. doi: 10.1016/j.ajpath.2014.12.005. Epub 2015 Feb 11.

12.

Muscle-specific signaling mechanism that links actin dynamics to serum response factor.

Kuwahara K, Barrientos T, Pipes GC, Li S, Olson EN.

Mol Cell Biol. 2005 Apr;25(8):3173-81.

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Redox modification of nuclear actin by MICAL-2 regulates SRF signaling.

Lundquist MR, Storaska AJ, Liu TC, Larsen SD, Evans T, Neubig RR, Jaffrey SR.

Cell. 2014 Jan 30;156(3):563-76. doi: 10.1016/j.cell.2013.12.035. Epub 2014 Jan 16.

16.

Mechanical regulation of the proangiogenic factor CCN1/CYR61 gene requires the combined activities of MRTF-A and CREB-binding protein histone acetyltransferase.

Hanna M, Liu H, Amir J, Sun Y, Morris SW, Siddiqui MA, Lau LF, Chaqour B.

J Biol Chem. 2009 Aug 21;284(34):23125-36. doi: 10.1074/jbc.M109.019059. Epub 2009 Jun 20.

17.

Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing.

Velasquez LS, Sutherland LB, Liu Z, Grinnell F, Kamm KE, Schneider JW, Olson EN, Small EM.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16850-5. doi: 10.1073/pnas.1316764110. Epub 2013 Sep 30.

18.

Fli-1 inhibits collagen type I production in dermal fibroblasts via an Sp1-dependent pathway.

Czuwara-Ladykowska J, Shirasaki F, Jackers P, Watson DK, Trojanowska M.

J Biol Chem. 2001 Jun 15;276(24):20839-48. Epub 2001 Mar 16.

19.

Regulation of myocardin factor protein stability by the LIM-only protein FHL2.

Hinson JS, Medlin MD, Taylor JM, Mack CP.

Am J Physiol Heart Circ Physiol. 2008 Sep;295(3):H1067-H1075. doi: 10.1152/ajpheart.91421.2007. Epub 2008 Jun 27.

20.

Contribution of serum response factor and myocardin to transcriptional regulation of smoothelins.

Rensen SS, Niessen PM, Long X, Doevendans PA, Miano JM, van Eys GJ.

Cardiovasc Res. 2006 Apr 1;70(1):136-45. Epub 2006 Jan 31.

PMID:
16451796

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