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Items: 1 to 20 of 129

1.

Aβ-induced formation of autophagosomes is mediated by RAGE-CaMKKβ-AMPK signaling.

Son SM, Jung ES, Shin HJ, Byun J, Mook-Jung I.

Neurobiol Aging. 2012 May;33(5):1006.e11-23. doi: 10.1016/j.neurobiolaging.2011.09.039. Epub 2011 Nov 1.

PMID:
22048125
2.

RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.

Cho HJ, Son SM, Jin SM, Hong HS, Shin DH, Kim SJ, Huh K, Mook-Jung I.

FASEB J. 2009 Aug;23(8):2639-49. doi: 10.1096/fj.08-126383. Epub 2009 Mar 30.

PMID:
19332646
3.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

4.

Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: involvement of non-amyloidogenic processing.

Hwang SH, Shin EJ, Shin TJ, Lee BH, Choi SH, Kang J, Kim HJ, Kwon SH, Jang CG, Lee JH, Kim HC, Nah SY.

J Alzheimers Dis. 2012;31(1):207-23. doi: 10.3233/JAD-2012-120439.

PMID:
22543851
5.

Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway.

Saadipour K, Yang M, Lim Y, Georgiou K, Sun Y, Keating D, Liu J, Wang YR, Gai WP, Zhong JH, Wang YJ, Zhou XF.

J Neurochem. 2013 Oct;127(2):152-62. doi: 10.1111/jnc.12383. Epub 2013 Aug 22.

6.

Aβ₁₋₄₂-RAGE interaction disrupts tight junctions of the blood-brain barrier via Ca²⁺-calcineurin signaling.

Kook SY, Hong HS, Moon M, Ha CM, Chang S, Mook-Jung I.

J Neurosci. 2012 Jun 27;32(26):8845-54. doi: 10.1523/JNEUROSCI.6102-11.2012.

7.

Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMP-activated protein kinase.

Chi Y, Li K, Yan Q, Koizumi S, Shi L, Takahashi S, Zhu Y, Matsue H, Takeda M, Kitamura M, Yao J.

J Pharmacol Exp Ther. 2011 Oct;339(1):257-66. doi: 10.1124/jpet.111.183020. Epub 2011 Jul 15.

8.

Apigenin, a chemopreventive bioflavonoid, induces AMP-activated protein kinase activation in human keratinocytes.

Tong X, Smith KA, Pelling JC.

Mol Carcinog. 2012 Mar;51(3):268-79. doi: 10.1002/mc.20793. Epub 2011 May 2.

PMID:
21538580
10.

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

Origlia N, Righi M, Capsoni S, Cattaneo A, Fang F, Stern DM, Chen JX, Schmidt AM, Arancio O, Yan SD, Domenici L.

J Neurosci. 2008 Mar 26;28(13):3521-30. doi: 10.1523/JNEUROSCI.0204-08.2008.

11.

AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure.

Thornton C, Bright NJ, Sastre M, Muckett PJ, Carling D.

Biochem J. 2011 Mar 15;434(3):503-12. doi: 10.1042/BJ20101485.

PMID:
21204788
12.

RAGE does not affect amyloid pathology in transgenic ArcAbeta mice.

Vodopivec I, Galichet A, Knobloch M, Bierhaus A, Heizmann CW, Nitsch RM.

Neurodegener Dis. 2009;6(5-6):270-80. doi: 10.1159/000261723. Epub 2010 Feb 10.

14.

Amyloid-beta peptides stimulate the expression of the p75(NTR) neurotrophin receptor in SHSY5Y human neuroblastoma cells and AD transgenic mice.

Chakravarthy B, Gaudet C, Ménard M, Atkinson T, Brown L, Laferla FM, Armato U, Whitfield J.

J Alzheimers Dis. 2010;19(3):915-25. doi: 10.3233/JAD-2010-1288.

PMID:
20157247
15.

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease.

Yu WH, Cuervo AM, Kumar A, Peterhoff CM, Schmidt SD, Lee JH, Mohan PS, Mercken M, Farmery MR, Tjernberg LO, Jiang Y, Duff K, Uchiyama Y, Näslund J, Mathews PM, Cataldo AM, Nixon RA.

J Cell Biol. 2005 Oct 10;171(1):87-98. Epub 2005 Oct 3.

16.

A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease.

Jeon S, Bose S, Hur J, Jun K, Kim YK, Cho KS, Koo BS.

J Ethnopharmacol. 2011 Sep 1;137(1):783-9. doi: 10.1016/j.jep.2011.06.046. Epub 2011 Jul 5.

PMID:
21762767
17.

Aβ-AGE aggravates cognitive deficit in rats via RAGE pathway.

Chen C, Li XH, Tu Y, Sun HT, Liang HQ, Cheng SX, Zhang S.

Neuroscience. 2014 Jan 17;257:1-10. doi: 10.1016/j.neuroscience.2013.10.056. Epub 2013 Nov 1.

PMID:
24188791
18.

Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism.

Lue LF, Walker DG, Brachova L, Beach TG, Rogers J, Schmidt AM, Stern DM, Yan SD.

Exp Neurol. 2001 Sep;171(1):29-45.

PMID:
11520119
19.

Decreased insulin-receptor signaling promotes the autophagic degradation of beta-amyloid peptide in C. elegans.

Florez-McClure ML, Hohsfield LA, Fonte G, Bealor MT, Link CD.

Autophagy. 2007 Nov-Dec;3(6):569-80. Epub 2007 Jul 20. Erratum in: Autophagy. 2009 Jan 1;5(1):132-3.

PMID:
17675890
20.

The novel RAGE interactor PRAK is associated with autophagy signaling in Alzheimer's disease pathogenesis.

Kim Y, Kim C, Son SM, Song H, Hong HS, Han SH, Mook-Jung I.

Mol Neurodegener. 2016 Jan 12;11:4. doi: 10.1186/s13024-016-0068-5.

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