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Items: 1 to 20 of 93

1.

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

Jennemann R, Rabionet M, Gorgas K, Epstein S, Dalpke A, Rothermel U, Bayerle A, van der Hoeven F, Imgrund S, Kirsch J, Nickel W, Willecke K, Riezman H, Gröne HJ, Sandhoff R.

Hum Mol Genet. 2012 Feb 1;21(3):586-608. doi: 10.1093/hmg/ddr494. Epub 2011 Oct 28.

PMID:
22038835
2.

Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.

Sassa T, Ohno Y, Suzuki S, Nomura T, Nishioka C, Kashiwagi T, Hirayama T, Akiyama M, Taguchi R, Shimizu H, Itohara S, Kihara A.

Mol Cell Biol. 2013 Jul;33(14):2787-96. doi: 10.1128/MCB.00192-13. Epub 2013 May 20.

3.

Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing.

Amen N, Mathow D, Rabionet M, Sandhoff R, Langbein L, Gretz N, Jäckel C, Gröne HJ, Jennemann R.

Hum Mol Genet. 2013 Oct 15;22(20):4164-79. doi: 10.1093/hmg/ddt264. Epub 2013 Jun 6.

PMID:
23748427
4.

2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length.

Mizutani Y, Kihara A, Chiba H, Tojo H, Igarashi Y.

J Lipid Res. 2008 Nov;49(11):2356-64. doi: 10.1194/jlr.M800158-JLR200. Epub 2008 Jun 9.

5.

Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation.

Mizutani Y, Sun H, Ohno Y, Sassa T, Wakashima T, Obara M, Yuyama K, Kihara A, Igarashi Y.

PLoS One. 2013 Jun 27;8(6):e67317. doi: 10.1371/journal.pone.0067317. Print 2013.

6.

Impaired epidermal ceramide synthesis causes autosomal recessive congenital ichthyosis and reveals the importance of ceramide acyl chain length.

Eckl KM, Tidhar R, Thiele H, Oji V, Hausser I, Brodesser S, Preil ML, Onal-Akan A, Stock F, Müller D, Becker K, Casper R, Nürnberg G, Altmüller J, Nürnberg P, Traupe H, Futerman AH, Hennies HC.

J Invest Dermatol. 2013 Sep;133(9):2202-11. doi: 10.1038/jid.2013.153. Epub 2013 Apr 2.

7.

Ceramide biosynthesis in keratinocyte and its role in skin function.

Mizutani Y, Mitsutake S, Tsuji K, Kihara A, Igarashi Y.

Biochimie. 2009 Jun;91(6):784-90. doi: 10.1016/j.biochi.2009.04.001. Epub 2009 Apr 11. Review.

PMID:
19364519
8.

Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis.

Jennemann R, Sandhoff R, Langbein L, Kaden S, Rothermel U, Gallala H, Sandhoff K, Wiegandt H, Gröne HJ.

J Biol Chem. 2007 Feb 2;282(5):3083-94. Epub 2006 Dec 4.

9.

Relationship between covalently bound ceramides and transepidermal water loss (TEWL).

Meguro S, Arai Y, Masukawa Y, Uie K, Tokimitsu I.

Arch Dermatol Res. 2000 Sep;292(9):463-8.

PMID:
11000290
10.

Altered expression of epidermal lipid bio-synthesis enzymes in atopic dermatitis skin is accompanied by changes in stratum corneum lipid composition.

Danso M, Boiten W, van Drongelen V, Gmelig Meijling K, Gooris G, El Ghalbzouri A, Absalah S, Vreeken R, Kezic S, van Smeden J, Lavrijsen S, Bouwstra J.

J Dermatol Sci. 2017 Oct;88(1):57-66. doi: 10.1016/j.jdermsci.2017.05.005. Epub 2017 May 18.

PMID:
28571749
11.

Vitamin C enhances differentiation of a continuous keratinocyte cell line (REK) into epidermis with normal stratum corneum ultrastructure and functional permeability barrier.

Pasonen-Seppänen S, Suhonen TM, Kirjavainen M, Suihko E, Urtti A, Miettinen M, Hyttinen M, Tammi M, Tammi R.

Histochem Cell Biol. 2001 Oct;116(4):287-97.

PMID:
11702187
12.

Corneocyte lipid envelope (CLE), the key structure for skin barrier function and ichthyosis pathogenesis.

Akiyama M.

J Dermatol Sci. 2017 Oct;88(1):3-9. doi: 10.1016/j.jdermsci.2017.06.002. Epub 2017 Jun 8. Review.

PMID:
28623042
13.

Omega-O-acylceramide, a lipid essential for mammalian survival.

Uchida Y, Holleran WM.

J Dermatol Sci. 2008 Aug;51(2):77-87. doi: 10.1016/j.jdermsci.2008.01.002. Epub 2008 Mar 10. Review.

PMID:
18329855
14.

Synthesis and degradation pathways, functions, and pathology of ceramides and epidermal acylceramides.

Kihara A.

Prog Lipid Res. 2016 Jul;63:50-69. doi: 10.1016/j.plipres.2016.04.001. Epub 2016 Apr 21. Review.

PMID:
27107674
15.

Ceramides and skin function.

Coderch L, López O, de la Maza A, Parra JL.

Am J Clin Dermatol. 2003;4(2):107-29. Review.

PMID:
12553851
16.

1-O-acylceramides are natural components of human and mouse epidermis.

Rabionet M, Bayerle A, Marsching C, Jennemann R, Gröne HJ, Yildiz Y, Wachten D, Shaw W, Shayman JA, Sandhoff R.

J Lipid Res. 2013 Dec;54(12):3312-21. doi: 10.1194/jlr.M040097. Epub 2013 Sep 27.

17.

Sphingolipid metabolism during epidermal barrier development in mice.

Doering T, Brade H, Sandhoff K.

J Lipid Res. 2002 Oct;43(10):1727-33.

18.

Exogenous lipids influence permeability barrier recovery in acetone-treated murine skin.

Man MQ, Feingold KR, Elias PM.

Arch Dermatol. 1993 Jun;129(6):728-38.

PMID:
8507075
20.

The skin's barrier.

Jensen JM, Proksch E.

G Ital Dermatol Venereol. 2009 Dec;144(6):689-700. Review.

PMID:
19907407

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