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Items: 1 to 20 of 107

1.

Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway.

Mao M, Sudhahar V, Ansenberger-Fricano K, Fernandes DC, Tanaka LY, Fukai T, Laurindo FR, Mason RP, Vasquez-Vivar J, Minshall RD, Stadler K, Bonini MG.

Free Radic Biol Med. 2012 Jan 15;52(2):427-35. doi: 10.1016/j.freeradbiomed.2011.09.020. Epub 2011 Oct 7.

2.

Depolarization of mitochondria in endothelial cells promotes cerebral artery vasodilation by activation of nitric oxide synthase.

Katakam PV, Wappler EA, Katz PS, Rutkai I, Institoris A, Domoki F, Gáspár T, Grovenburg SM, Snipes JA, Busija DW.

Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):752-9. doi: 10.1161/ATVBAHA.112.300560. Epub 2013 Jan 17.

3.

Rumex acetosa L. induces vasorelaxation in rat aorta via activation of PI3-kinase/Akt- AND Ca(2+)-eNOS-NO signaling in endothelial cells.

Sun YY, Su XH, Jin JY, Zhou ZQ, Sun SS, Wen JF, Kang DG, Lee HS, Cho KW, Jin SN.

J Physiol Pharmacol. 2015 Dec;66(6):907-15.

4.

CCN1 acutely increases nitric oxide production via integrin αvβ3-Akt-S6K-phosphorylation of endothelial nitric oxide synthase at the serine 1177 signaling axis.

Hwang S, Lee HJ, Kim G, Won KJ, Park YS, Jo I.

Free Radic Biol Med. 2015 Dec;89:229-40. doi: 10.1016/j.freeradbiomed.2015.08.005. Epub 2015 Sep 21.

PMID:
26393424
5.

Nitroglycerin-induced endothelial dysfunction and tolerance involve adverse phosphorylation and S-Glutathionylation of endothelial nitric oxide synthase: beneficial effects of therapy with the AT1 receptor blocker telmisartan.

Knorr M, Hausding M, Kröller-Schuhmacher S, Steven S, Oelze M, Heeren T, Scholz A, Gori T, Wenzel P, Schulz E, Daiber A, Münzel T.

Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2223-31. doi: 10.1161/ATVBAHA.111.232058. Epub 2011 Jul 14.

6.

Constitutive nitric oxide synthase activation is a significant route for nitroglycerin-mediated vasodilation.

Bonini MG, Stadler K, Silva SO, Corbett J, Dore M, Petranka J, Fernandes DC, Tanaka LY, Duma D, Laurindo FR, Mason RP.

Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8569-74. doi: 10.1073/pnas.0708615105. Epub 2008 Jun 18.

7.

Propionyl-L-carnitine induces eNOS activation and nitric oxide synthesis in endothelial cells via PI3 and Akt kinases.

Ning WH, Zhao K.

Vascul Pharmacol. 2013 Sep-Oct;59(3-4):76-82. doi: 10.1016/j.vph.2013.07.001. Epub 2013 Jul 12.

PMID:
23850990
8.

PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation.

Gupta A, Anjomani-Virmouni S, Koundouros N, Dimitriadi M, Choo-Wing R, Valle A, Zheng Y, Chiu YH, Agnihotri S, Zadeh G, Asara JM, Anastasiou D, Arends MJ, Cantley LC, Poulogiannis G.

Mol Cell. 2017 Mar 16;65(6):999-1013.e7. doi: 10.1016/j.molcel.2017.02.019.

9.

Activation of NAD(P)H:quinone oxidoreductase ameliorates spontaneous hypertension in an animal model via modulation of eNOS activity.

Kim YH, Hwang JH, Noh JR, Gang GT, Kim DH, Son HY, Kwak TH, Shong M, Lee IK, Lee CH.

Cardiovasc Res. 2011 Aug 1;91(3):519-27. doi: 10.1093/cvr/cvr110. Epub 2011 Apr 18.

PMID:
21502369
10.

Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats.

Nemoto S, Kobayashi T, Taguchi K, Matsumoto T, Kamata K.

Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2383-94. doi: 10.1152/ajpheart.00178.2011. Epub 2011 Sep 16.

11.

Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways.

Pan C, Lou L, Huo Y, Singh G, Chen M, Zhang D, Wu A, Zhao M, Wang S, Li J.

Ther Adv Cardiovasc Dis. 2011 Apr;5(2):99-111. doi: 10.1177/1753944710396538. Epub 2011 Jan 31.

PMID:
21282198
12.

Nitroglycerin tolerance in caveolin-1 deficient mice.

Mao M, Varadarajan S, Fukai T, Bakhshi FR, Chernaya O, Dudley SC Jr, Minshall RD, Bonini MG.

PLoS One. 2014 Aug 26;9(8):e104101. doi: 10.1371/journal.pone.0104101. eCollection 2014.

14.

Estrogen induced changes in Akt-dependent activation of endothelial nitric oxide synthase and vasodilation.

Florian M, Lu Y, Angle M, Magder S.

Steroids. 2004 Sep;69(10):637-45.

PMID:
15465108
15.

Therapeutically relevant concentrations of raloxifene dilate pressurized rat resistance arteries via calcium-dependent endothelial nitric oxide synthase activation.

Chan YC, Leung FP, Wong WT, Tian XY, Yung LM, Lau CW, Tsang SY, Yao X, Chen ZY, Huang Y.

Arterioscler Thromb Vasc Biol. 2010 May;30(5):992-9. doi: 10.1161/ATVBAHA.110.203935. Epub 2010 Feb 25.

16.

Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.

Ching LC, Kou YR, Shyue SK, Su KH, Wei J, Cheng LC, Yu YB, Pan CC, Lee TS.

Cardiovasc Res. 2011 Aug 1;91(3):492-501. doi: 10.1093/cvr/cvr104. Epub 2011 Apr 14.

PMID:
21493704
17.

Age impairs Flk-1 signaling and NO-mediated vasodilation in coronary arterioles.

LeBlanc AJ, Shipley RD, Kang LS, Muller-Delp JM.

Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2280-8. doi: 10.1152/ajpheart.00541.2008. Epub 2008 Oct 3.

18.

Contribution of insulin and Akt1 signaling to endothelial nitric oxide synthase in the regulation of endothelial function and blood pressure.

Symons JD, McMillin SL, Riehle C, Tanner J, Palionyte M, Hillas E, Jones D, Cooksey RC, Birnbaum MJ, McClain DA, Zhang QJ, Gale D, Wilson LJ, Abel ED.

Circ Res. 2009 May 8;104(9):1085-94. doi: 10.1161/CIRCRESAHA.108.189316. Epub 2009 Apr 2.

19.

Role of PTEN in modulation of ADP-dependent signaling pathways in vascular endothelial cells.

Bretón-Romero R, Kalwa H, Lamas S, Michel T.

Biochim Biophys Acta. 2013 Dec;1833(12):2586-2595. doi: 10.1016/j.bbamcr.2013.06.009. Epub 2013 Jun 25.

20.

Adiponectin stimulates production of nitric oxide in vascular endothelial cells.

Chen H, Montagnani M, Funahashi T, Shimomura I, Quon MJ.

J Biol Chem. 2003 Nov 7;278(45):45021-6. Epub 2003 Aug 27.

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