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Items: 1 to 20 of 90

1.
2.

Synergistic toxic interactions between CYP2E1, LPS/TNFα, and JNK/p38 MAP kinase and their implications in alcohol-induced liver injury.

Cederbaum AI, Lu Y, Wang X, Wu D.

Adv Exp Med Biol. 2015;815:145-72. doi: 10.1007/978-3-319-09614-8_9. Review.

PMID:
25427906
4.

Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor alpha liver injury.

Wu D, Cederbaum A.

Free Radic Biol Med. 2010 Aug 1;49(3):348-60. doi: 10.1016/j.freeradbiomed.2010.04.021. Epub 2010 May 14.

6.

Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells.

Yang L, Wu D, Wang X, Cederbaum AI.

Free Radic Biol Med. 2011 Jul 1;51(1):185-96. doi: 10.1016/j.freeradbiomed.2011.04.030. Epub 2011 Apr 22.

8.

Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase.

Wang X, Lu Y, Xie B, Cederbaum AI.

Free Radic Biol Med. 2009 Sep 1;47(5):518-28. doi: 10.1016/j.freeradbiomed.2009.05.021. Epub 2009 May 27.

9.

Role of nitric oxide and nuclear factor-kappaB in the CYP2E1 potentiation of tumor necrosis factor alpha hepatotoxicity in mice.

Wu D, Xu C, Cederbaum A.

Free Radic Biol Med. 2009 Feb 15;46(4):480-91. doi: 10.1016/j.freeradbiomed.2008.11.001. Epub 2008 Nov 19.

PMID:
19063961
10.
12.

Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity.

Wu D, Cederbaum A.

Toxicol Appl Pharmacol. 2006 Oct 15;216(2):282-92. Epub 2006 Jul 1.

PMID:
16938321
13.

Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1.

Wu D, Cederbaum AI.

Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):70-6. Review.

PMID:
16019049
14.

Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice.

Zhuge J, Cederbaum AI.

Free Radic Biol Med. 2009 Feb 1;46(3):406-13. doi: 10.1016/j.freeradbiomed.2008.10.037. Epub 2008 Oct 31.

15.

Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver.

Yang L, Wu D, Wang X, Cederbaum AI.

Free Radic Biol Med. 2012 Sep 1;53(5):1170-80. doi: 10.1016/j.freeradbiomed.2012.06.029. Epub 2012 Jun 27.

16.

Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway.

Gong P, Cederbaum AI, Nieto N.

J Biol Chem. 2003 Aug 8;278(32):29693-700. Epub 2003 May 30.

17.

Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole.

Lu Y, Wang X, Cederbaum AI.

Am J Physiol Gastrointest Liver Physiol. 2005 Aug;289(2):G308-19. Epub 2005 Apr 21.

18.

CYP2E1-dependent toxicity and oxidative stress in HepG2 cells.

Cederbaum AI, Wu D, Mari M, Bai J.

Free Radic Biol Med. 2001 Dec 15;31(12):1539-43. Review.

PMID:
11744327
19.
20.

Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity.

Wu D, Cederbaum AI.

J Biol Chem. 2003 Jan 10;278(2):1115-24. Epub 2002 Oct 25.

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