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Items: 1 to 20 of 232

1.

Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation.

Hybertson BM, Gao B, Bose SK, McCord JM.

Mol Aspects Med. 2011 Aug;32(4-6):234-46. doi: 10.1016/j.mam.2011.10.006. Epub 2011 Oct 15. Review.

2.

Antioxidants and phase 2 enzymes in macrophages: regulation by Nrf2 signaling and protection against oxidative and electrophilic stress.

Zhu H, Jia Z, Zhang L, Yamamoto M, Misra HP, Trush MA, Li Y.

Exp Biol Med (Maywood). 2008 Apr;233(4):463-74. doi: 10.3181/0711-RM-304.

PMID:
18367636
3.

Nuclear factor erythroid 2-related factor 2 signaling in Parkinson disease: a promising multi therapeutic target against oxidative stress, neuroinflammation and cell death.

Kumar H, Koppula S, Kim IS, More SV, Kim BW, Choi DK.

CNS Neurol Disord Drug Targets. 2012 Dec;11(8):1015-29. Review.

PMID:
23244425
4.

Nrf2 and antioxidant defense against CYP2E1 toxicity.

Cederbaum A.

Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1223-44. doi: 10.1517/17425250903143769. Review.

PMID:
19671018
5.

Heat stress activates interleukin-8 and the antioxidant system via Nrf2 pathways in human dental pulp cells.

Chang SW, Lee SI, Bae WJ, Min KS, Shin ES, Oh GS, Pae HO, Kim EC.

J Endod. 2009 Sep;35(9):1222-8. doi: 10.1016/j.joen.2009.06.005.

PMID:
19720220
6.

NRF2 targeting: a promising therapeutic strategy in chronic obstructive pulmonary disease.

Boutten A, Goven D, Artaud-Macari E, Boczkowski J, Bonay M.

Trends Mol Med. 2011 Jul;17(7):363-71. doi: 10.1016/j.molmed.2011.02.006. Epub 2011 Apr 1. Review.

PMID:
21459041
7.

Nrf2-ARE stress response mechanism: a control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases.

Singh S, Vrishni S, Singh BK, Rahman I, Kakkar P.

Free Radic Res. 2010 Nov;44(11):1267-88. doi: 10.3109/10715762.2010.507670. Review.

PMID:
20815789
8.
9.

Fumarates promote cytoprotection of central nervous system cells against oxidative stress via the nuclear factor (erythroid-derived 2)-like 2 pathway.

Scannevin RH, Chollate S, Jung MY, Shackett M, Patel H, Bista P, Zeng W, Ryan S, Yamamoto M, Lukashev M, Rhodes KJ.

J Pharmacol Exp Ther. 2012 Apr;341(1):274-84. doi: 10.1124/jpet.111.190132. Epub 2012 Jan 20.

PMID:
22267202
10.

The nuclear matrix protein, NRP/B, enhances Nrf2-mediated oxidative stress responses in breast cancer cells.

Seng S, Avraham HK, Jiang S, Yang S, Sekine M, Kimelman N, Li H, Avraham S.

Cancer Res. 2007 Sep 15;67(18):8596-604.

11.

The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders.

van Muiswinkel FL, Kuiperij HB.

Curr Drug Targets CNS Neurol Disord. 2005 Jun;4(3):267-81. Review.

PMID:
15975029
12.

[Protective role of Nrf2 in the lungs against oxidative airway diseases].

Boutten A, Goven D, Artaud-Macari E, Bonay M.

Med Sci (Paris). 2011 Nov;27(11):966-72. doi: 10.1051/medsci/20112711012. Epub 2011 Nov 30. Review. French.

13.
14.

Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge.

Donovan EL, McCord JM, Reuland DJ, Miller BF, Hamilton KL.

Oxid Med Cell Longev. 2012;2012:132931. doi: 10.1155/2012/132931. Epub 2012 May 22.

15.

Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?

de Vries HE, Witte M, Hondius D, Rozemuller AJ, Drukarch B, Hoozemans J, van Horssen J.

Free Radic Biol Med. 2008 Nov 15;45(10):1375-83. doi: 10.1016/j.freeradbiomed.2008.09.001. Epub 2008 Sep 13. Review.

PMID:
18824091
16.

Regulation of the Nrf2 antioxidant pathway by microRNAs: New players in micromanaging redox homeostasis.

Cheng X, Ku CH, Siow RC.

Free Radic Biol Med. 2013 Sep;64:4-11. doi: 10.1016/j.freeradbiomed.2013.07.025. Epub 2013 Jul 21. Review.

PMID:
23880293
17.

Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin.

Crespo I, Miguel BS, Laliena A, Alvarez M, Culebras JM, González-Gallego J, Tuñón MJ.

J Pineal Res. 2010 Sep;49(2):193-200. doi: 10.1111/j.1600-079X.2010.00787.x. Epub 2010 Jul 1.

PMID:
20609075
18.

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid.

Pi J, Zhang Q, Woods CG, Wong V, Collins S, Andersen ME.

Toxicol Appl Pharmacol. 2008 Feb 1;226(3):236-43. Epub 2007 Sep 26.

PMID:
17980396
19.

Targeting the Nrf2 pathway against cardiovascular disease.

Li J, Ichikawa T, Janicki JS, Cui T.

Expert Opin Ther Targets. 2009 Jul;13(7):785-94. doi: 10.1517/14728220903025762. Review.

PMID:
19530984
20.

Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells.

Martín MA, Ramos S, Granado-Serrano AB, Rodríguez-Ramiro I, Trujillo M, Bravo L, Goya L.

Mol Nutr Food Res. 2010 Jul;54(7):956-66. doi: 10.1002/mnfr.200900159.

PMID:
20166143

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