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Items: 1 to 20 of 150

1.

Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.

Palazzo AL, Evensen E, Huang YW, Cesano A, Nolan GP, Fantl WJ.

PLoS One. 2011;6(10):e24592. doi: 10.1371/journal.pone.0024592. Epub 2011 Oct 10.

2.

Differential induction of apoptosis by fludarabine monophosphate in leukemic B and normal T cells in chronic lymphocytic leukemia.

Consoli U, El-Tounsi I, Sandoval A, Snell V, Kleine HD, Brown W, Robinson JR, DiRaimondo F, Plunkett W, Andreeff M.

Blood. 1998 Mar 1;91(5):1742-8.

3.

Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine.

Shanafelt TD, Lee YK, Bone ND, Strege AK, Narayanan VL, Sausville EA, Geyer SM, Kaufmann SH, Kay NE.

Blood. 2005 Mar 1;105(5):2099-106. Epub 2004 Sep 23.

5.

The selective SYK inhibitor P505-15 (PRT062607) inhibits B cell signaling and function in vitro and in vivo and augments the activity of fludarabine in chronic lymphocytic leukemia.

Spurgeon SE, Coffey G, Fletcher LB, Burke R, Tyner JW, Druker BJ, Betz A, DeGuzman F, Pak Y, Baker D, Pandey A, Hollenbach SJ, Sinha U, Loriaux MM.

J Pharmacol Exp Ther. 2013 Feb;344(2):378-87. doi: 10.1124/jpet.112.200832. Epub 2012 Dec 7.

6.

Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.

Kashyap MK, Amaya-Chanaga CI, Kumar D, Simmons B, Huser N, Gu Y, Hallin M, Lindquist K, Yafawi R, Choi MY, Amine AA, Rassenti LZ, Zhang C, Liu SH, Smeal T, Fantin VR, Kipps TJ, Pernasetti F, Castro JE.

J Hematol Oncol. 2017 May 19;10(1):112. doi: 10.1186/s13045-017-0435-x.

7.

Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.

Palomba ML, Piersanti K, Ziegler CG, Decker H, Cotari JW, Bantilan K, Rijo I, Gardner JR, Heaney M, Bemis D, Balderas R, Malek SN, Seymour E, Zelenetz AD, van den Brink MR, Altan-Bonnet G.

PLoS One. 2014 Jan 29;9(1):e79987. doi: 10.1371/journal.pone.0079987. eCollection 2014.

8.

Expression of CD10 by B-chronic lymphocytic leukemia cells undergoing apoptosis in vivo and in vitro.

Morabito F, Mangiola M, Rapezzi D, Zupo S, Oliva BM, Ferraris AM, Spriano M, Rossi E, Stelitano C, Callea V, Cutrona G, Ferrarini M.

Haematologica. 2003 Aug;88(8):864-73.

9.
10.

Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells.

Liang X, Moseman EA, Farrar MA, Bachanova V, Weisdorf DJ, Blazar BR, Chen W.

Blood. 2010 Jun 17;115(24):5041-52. doi: 10.1182/blood-2009-03-213363. Epub 2010 Mar 25.

11.

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.

Baudot AD, Jeandel PY, Mouska X, Maurer U, Tartare-Deckert S, Raynaud SD, Cassuto JP, Ticchioni M, Deckert M.

Oncogene. 2009 Sep 17;28(37):3261-73. doi: 10.1038/onc.2009.179. Epub 2009 Jul 6.

PMID:
19581935
12.

Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances.

Perez-Chacon G, Martinez-Laperche C, Rebolleda N, Somovilla-Crespo B, Muñoz-Calleja C, Buño I, Zapata JM.

Clin Cancer Res. 2016 Jan 1;22(1):134-45. doi: 10.1158/1078-0432.CCR-15-0736. Epub 2015 Aug 31. Erratum in: Clin Cancer Res. 2017 Jun 15;23 (12 ):3226.

13.

Modulation of IL-4 level by fludarabine and its relation to apoptosis in chronic B-cell lymphocytic leukemia.

Shamaa LA, Hussein Ael-S, Balbaa OA, Farahat NM, Ali MA.

Egypt J Immunol. 2008;15(1):181-92.

PMID:
20306682
14.

Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro.

Ganeshaguru K, Wickremasinghe RG, Jones DT, Gordon M, Hart SM, Virchis AE, Prentice HG, Hoffbrand AV, Man A, Champain K, Csermak K, Mehta AB.

Haematologica. 2002 Feb;87(2):167-76.

15.

Fludarabine ability to down-regulate Bcl-2 gene product in CD5+ leukaemic B cells: in vitro/in vivo correlations.

Gottardi D, De Leo AM, Alfarano A, Stacchini A, Circosta P, Gregoretti MG, Bergui L, Aragno M, Caligaris-Cappio F.

Br J Haematol. 1997 Oct;99(1):147-57.

PMID:
9359515
16.

Targeting lipid metabolism by the lipoprotein lipase inhibitor orlistat results in apoptosis of B-cell chronic lymphocytic leukemia cells.

Pallasch CP, Schwamb J, Königs S, Schulz A, Debey S, Kofler D, Schultze JL, Hallek M, Ultsch A, Wendtner CM.

Leukemia. 2008 Mar;22(3):585-92. Epub 2007 Dec 13.

PMID:
18079738
17.

Vitro drug-induced apoptosis in freshly isolated leukemic cells: a flow cytometric analysis.

Stagno F, Impera S, Italia P, Corsaro F, Cacciola E Jr, Guglielmo P.

Boll Soc Ital Biol Sper. 1995 Mar-Apr;71(3-4):99-104.

PMID:
7646876
18.

Drug induction apoptosis assay as predictive value of chemotherapy response in patients with B-cell chronic lymphocytic leukemia.

Castejón R, Yebra M, Citores MJ, Villarreal M, García-Marco JA, Vargas JA.

Leuk Lymphoma. 2009 Apr;50(4):593-603. doi: 10.1080/10428190902780669.

PMID:
19373658
19.

Physical contact with endothelial cells through β1- and β2- integrins rescues chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile in leukemic cells.

Maffei R, Fiorcari S, Bulgarelli J, Martinelli S, Castelli I, Deaglio S, Debbia G, Fontana M, Coluccio V, Bonacorsi G, Zucchini P, Narni F, Torelli G, Luppi M, Marasca R.

Haematologica. 2012 Jun;97(6):952-60. doi: 10.3324/haematol.2011.054924. Epub 2011 Dec 29.

20.

Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia.

Scupoli MT, Pizzolo G.

Expert Rev Hematol. 2012 Jun;5(3):341-8. doi: 10.1586/ehm.12.21. Review.

PMID:
22780213

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