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Items: 1 to 20 of 330

1.

H5N1 influenza virus-induced mediators upregulate RIG-I in uninfected cells by paracrine effects contributing to amplified cytokine cascades.

Hui KP, Lee SM, Cheung CY, Mao H, Lai AK, Chan RW, Chan MC, Tu W, Guan Y, Lau YL, Peiris JS.

J Infect Dis. 2011 Dec 15;204(12):1866-78. doi: 10.1093/infdis/jir665. Epub 2011 Oct 19.

PMID:
22013225
2.

Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK.

Hui KP, Lee SM, Cheung CY, Ng IH, Poon LL, Guan Y, Ip NY, Lau AS, Peiris JS.

J Immunol. 2009 Jan 15;182(2):1088-98.

3.

Systems-level comparison of host-responses elicited by avian H5N1 and seasonal H1N1 influenza viruses in primary human macrophages.

Lee SM, Gardy JL, Cheung CY, Cheung TK, Hui KP, Ip NY, Guan Y, Hancock RE, Peiris JS.

PLoS One. 2009 Dec 14;4(12):e8072. doi: 10.1371/journal.pone.0008072.

4.
5.

RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression.

Mäkelä SM, Österlund P, Westenius V, Latvala S, Diamond MS, Gale M Jr, Julkunen I.

J Virol. 2015 Dec;89(23):12014-25. doi: 10.1128/JVI.01576-15. Epub 2015 Sep 16.

6.

Type I IFN triggers RIG-I/TLR3/NLRP3-dependent inflammasome activation in influenza A virus infected cells.

Pothlichet J, Meunier I, Davis BK, Ting JP, Skamene E, von Messling V, Vidal SM.

PLoS Pathog. 2013;9(4):e1003256. doi: 10.1371/journal.ppat.1003256. Epub 2013 Apr 11.

7.

Interferon dysregulation and virus-induced cell death in avian influenza H5N1 virus infections.

Lee DC, Law AH, Hui K, Tam AH, Peiris JS, Lau AS.

Hong Kong Med J. 2012 Feb;18 Suppl 2:12-6.

8.

Phosphatidylinositol-3-kinase (PI3K) is activated by influenza virus vRNA via the pathogen pattern receptor Rig-I to promote efficient type I interferon production.

Hrincius ER, Dierkes R, Anhlan D, Wixler V, Ludwig S, Ehrhardt C.

Cell Microbiol. 2011 Dec;13(12):1907-19. doi: 10.1111/j.1462-5822.2011.01680.x. Epub 2011 Oct 11.

PMID:
21899695
9.

Seasonal and pandemic influenza H1N1 viruses induce differential expression of SOCS-1 and RIG-I genes and cytokine/chemokine production in macrophages.

Ramírez-Martínez G, Cruz-Lagunas A, Jiménez-Alvarez L, Espinosa E, Ortíz-Quintero B, Santos-Mendoza T, Herrera MT, Canché-Pool E, Mendoza C, Bañales JL, García-Moreno SA, Morán J, Cabello C, Orozco L, Aguilar-Delfín I, Hidalgo-Miranda A, Romero S, Suratt BT, Selman M, Zúñiga J.

Cytokine. 2013 Apr;62(1):151-9. doi: 10.1016/j.cyto.2013.01.018. Epub 2013 Feb 21.

10.

Influenza A(H1N1)pdm09 virus suppresses RIG-I initiated innate antiviral responses in the human lung.

Wu W, Zhang W, Booth JL, Metcalf JP.

PLoS One. 2012;7(11):e49856. doi: 10.1371/journal.pone.0049856. Epub 2012 Nov 21.

11.

Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.

Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, García-Sastre A, Katze MG, Gale M Jr.

J Virol. 2008 Jan;82(1):335-45. Epub 2007 Oct 17.

12.

Protein kinase regulated by dsRNA downregulates the interferon production in dengue virus- and dsRNA-stimulated human lung epithelial cells.

Li Y, Xie J, Wu S, Xia J, Zhang P, Liu C, Zhang P, Huang X.

PLoS One. 2013;8(1):e55108. doi: 10.1371/journal.pone.0055108. Epub 2013 Jan 25.

14.

Mammalian innate resistance to highly pathogenic avian influenza H5N1 virus infection is mediated through reduced proinflammation and infectious virus release.

Nelli RK, Dunham SP, Kuchipudi SV, White GA, Baquero-Perez B, Chang P, Ghaemmaghami A, Brookes SM, Brown IH, Chang KC.

J Virol. 2012 Sep;86(17):9201-10. doi: 10.1128/JVI.00244-12. Epub 2012 Jun 20.

15.

Contribution of IPS-1 to polyI:C-induced cytokine production in conjunctival epithelial cells.

Ueta M, Kawai T, Yokoi N, Akira S, Kinoshita S.

Biochem Biophys Res Commun. 2011 Jan 7;404(1):419-23. doi: 10.1016/j.bbrc.2010.11.136. Epub 2010 Dec 3.

PMID:
21130742
16.

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication.

Ranjan P, Jayashankar L, Deyde V, Zeng H, Davis WG, Pearce MB, Bowzard JB, Hoelscher MA, Jeisy-Scott V, Wiens ME, Gangappa S, Gubareva L, García-Sastre A, Katz JM, Tumpey TM, Fujita T, Sambhara S.

Virol J. 2010 May 21;7:102. doi: 10.1186/1743-422X-7-102.

17.

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential.

Oshiumi H, Sakai K, Matsumoto M, Seya T.

Eur J Immunol. 2010 Apr;40(4):940-8. doi: 10.1002/eji.200940203.

18.

Andrographolide as an anti-H1N1 drug and the mechanism related to retinoic acid-inducible gene-I-like receptors signaling pathway.

Yu B, Dai CQ, Jiang ZY, Li EQ, Chen C, Wu XL, Chen J, Liu Q, Zhao CL, He JX, Ju DH, Chen XY.

Chin J Integr Med. 2014 Jul;20(7):540-5. doi: 10.1007/s11655-014-1860-0. Epub 2014 Jun 28.

PMID:
24972581
19.

Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells.

Chan MC, Cheung CY, Chui WH, Tsao SW, Nicholls JM, Chan YO, Chan RW, Long HT, Poon LL, Guan Y, Peiris JS.

Respir Res. 2005 Nov 11;6:135.

20.

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways.

Melchjorsen J, Rintahaka J, Søby S, Horan KA, Poltajainen A, Østergaard L, Paludan SR, Matikainen S.

J Virol. 2010 Nov;84(21):11350-8. doi: 10.1128/JVI.01106-10. Epub 2010 Aug 25.

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