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Items: 1 to 20 of 94


Triple SILAC to determine stimulus specific interactions in the Wnt pathway.

Hilger M, Mann M.

J Proteome Res. 2012 Feb 3;11(2):982-94. doi: 10.1021/pr200740a. Epub 2011 Nov 18.


Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.

Wang Z, Tacchelly-Benites O, Yang E, Thorne CA, Nojima H, Lee E, Ahmed Y.

Genetics. 2016 May;203(1):269-81. doi: 10.1534/genetics.115.183244. Epub 2016 Mar 14.


Negative-feedback regulation of the Wnt pathway by conductin/axin2 involves insensitivity to upstream signalling.

Bernkopf DB, Hadjihannas MV, Behrens J.

J Cell Sci. 2015 Jan 1;128(1):33-9. doi: 10.1242/jcs.159145. Epub 2014 Nov 6.


Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3.

Lee YN, Gao Y, Wang HY.

Cell Signal. 2008 Feb;20(2):443-52. Epub 2007 Nov 17.


The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein.

Wei W, Li M, Wang J, Nie F, Li L.

Mol Cell Biol. 2012 Oct;32(19):3903-12. doi: 10.1128/MCB.00251-12. Epub 2012 Jul 23.


Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through blocking autophagic degradation of dishevelled2.

Geng Y, Ju Y, Ren F, Qiu Y, Tomita Y, Tomoeda M, Kishida M, Wang Y, Jin L, Su F, Wei C, Jia B, Li Y, Chang Z.

J Biol Chem. 2014 Apr 18;289(16):11230-41. doi: 10.1074/jbc.M113.544999. Epub 2014 Mar 10.


Modulation of Wnt signaling by Axin and Axil.

Kikuchi A.

Cytokine Growth Factor Rev. 1999 Sep-Dec;10(3-4):255-65. Review.


Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signalling.

Brauburger K, Akyildiz S, Ruppert JG, Graeb M, Bernkopf DB, Hadjihannas MV, Behrens J.

FEBS J. 2014 Feb;281(3):787-801. doi: 10.1111/febs.12624. Epub 2013 Dec 12.


New steps in the Wnt/beta-catenin signal transduction pathway.

Sakanaka C, Sun TQ, Williams LT.

Recent Prog Horm Res. 2000;55:225-36. Review.


Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity.

Valvezan AJ, Zhang F, Diehl JA, Klein PS.

J Biol Chem. 2012 Feb 3;287(6):3823-32. doi: 10.1074/jbc.M111.323337. Epub 2011 Dec 19.


[Mechanism of Wnt signaling pathway regulation by a truncated mutant of Axin2 in colorectal cancer].

Wang FW, Wen L, Zhu SW, Yao Q, Cai YM, Ma G.

Ai Zheng. 2007 Oct;26(10):1041-6. Chinese.


Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization.

Fagotto F, Jho Eh, Zeng L, Kurth T, Joos T, Kaufmann C, Costantini F.

J Cell Biol. 1999 May 17;145(4):741-56.


Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.

Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT.

Science. 2007 May 18;316(5827):1043-6.


Dishevelled-2 docks and activates Src in a Wnt-dependent manner.

Yokoyama N, Malbon CC.

J Cell Sci. 2009 Dec 15;122(Pt 24):4439-51. doi: 10.1242/jcs.051847. Epub 2009 Nov 17.


The ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signaling.

Lui TT, Lacroix C, Ahmed SM, Goldenberg SJ, Leach CA, Daulat AM, Angers S.

Mol Cell Biol. 2011 May;31(10):2053-65. doi: 10.1128/MCB.01094-10. Epub 2011 Mar 7.


Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.

Pfister AS, Tanneberger K, Schambony A, Behrens J.

J Biol Chem. 2012 Jan 13;287(3):1734-41. doi: 10.1074/jbc.M111.308650. Epub 2011 Nov 28.


HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.

Tran H, Bustos D, Yeh R, Rubinfeld B, Lam C, Shriver S, Zilberleyb I, Lee MW, Phu L, Sarkar AA, Zohn IE, Wertz IE, Kirkpatrick DS, Polakis P.

J Biol Chem. 2013 Feb 8;288(6):3753-67. doi: 10.1074/jbc.M112.415240. Epub 2012 Dec 31.


Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling.

Wang Z, Tacchelly-Benites O, Yang E, Ahmed Y.

PLoS Genet. 2016 Dec 13;12(12):e1006494. doi: 10.1371/journal.pgen.1006494. eCollection 2016 Dec.

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