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Items: 1 to 20 of 101

1.

Genetic determinants of serum testosterone concentrations in men.

Ohlsson C, Wallaschofski H, Lunetta KL, Stolk L, Perry JR, Koster A, Petersen AK, Eriksson J, Lehtimäki T, Huhtaniemi IT, Hammond GL, Maggio M, Coviello AD; EMAS Study Group., Ferrucci L, Heier M, Hofman A, Holliday KL, Jansson JO, Kähönen M, Karasik D, Karlsson MK, Kiel DP, Liu Y, Ljunggren O, Lorentzon M, Lyytikäinen LP, Meitinger T, Mellström D, Melzer D, Miljkovic I, Nauck M, Nilsson M, Penninx B, Pye SR, Vasan RS, Reincke M, Rivadeneira F, Tajar A, Teumer A, Uitterlinden AG, Ulloor J, Viikari J, Völker U, Völzke H, Wichmann HE, Wu TS, Zhuang WV, Ziv E, Wu FC, Raitakari O, Eriksson A, Bidlingmaier M, Harris TB, Murray A, de Jong FH, Murabito JM, Bhasin S, Vandenput L, Haring R.

PLoS Genet. 2011 Oct;7(10):e1002313. doi: 10.1371/journal.pgen.1002313. Epub 2011 Oct 6.

2.

A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.

Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR.

PLoS Genet. 2012;8(7):e1002805. doi: 10.1371/journal.pgen.1002805. Epub 2012 Jul 19.

3.

Polymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men.

Vanbillemont G, Bogaert V, De Bacquer D, Lapauw B, Goemaere S, Toye K, Van Steen K, Taes Y, Kaufman JM.

Clin Endocrinol (Oxf). 2009 Feb;70(2):303-10. doi: 10.1111/j.1365-2265.2008.03365.x. Epub 2008 Aug 4.

PMID:
18681858
4.

Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.

Jin G, Sun J, Kim ST, Feng J, Wang Z, Tao S, Chen Z, Purcell L, Smith S, Isaacs WB, Rittmaster RS, Zheng SL, Condreay LD, Xu J.

Hum Mol Genet. 2012 Dec 1;21(23):5222-8. doi: 10.1093/hmg/dds361. Epub 2012 Aug 30.

5.

Influence of SHBG gene pentanucleotide TAAAA repeat and D327N polymorphism on serum sex hormone-binding globulin concentration in hirsute women.

Cousin P, Calemard-Michel L, Lejeune H, Raverot G, Yessaad N, Emptoz-Bonneton A, Morel Y, Pugeat M.

J Clin Endocrinol Metab. 2004 Feb;89(2):917-24.

PMID:
14764814
6.

Single-nucleotide polymorphism, rs1799941 in the Sex Hormone-Binding Globulin (SHBG) gene, related to both serum testosterone and SHBG levels and the risk of myocardial infarction, type 2 diabetes, cancer and mortality in men: the Tromsø Study.

Svartberg J, Schirmer H, Wilsgaard T, Mathiesen EB, Njølstad I, Løchen ML, Jorde R.

Andrology. 2014 Mar;2(2):212-8. doi: 10.1111/j.2047-2927.2013.00174.x. Epub 2013 Dec 10.

7.

Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men.

Chen Z, Tao S, Gao Y, Zhang J, Hu Y, Mo L, Kim ST, Yang X, Tan A, Zhang H, Qin X, Li L, Wu Y, Zhang S, Zheng SL, Xu J, Mo Z, Sun J.

J Med Genet. 2013 Dec;50(12):794-801. doi: 10.1136/jmedgenet-2013-101705. Epub 2013 Sep 18.

PMID:
24049095
8.

Mendelian randomization suggests non-causal associations of testosterone with cardiometabolic risk factors and mortality.

Haring R, Teumer A, Völker U, Dörr M, Nauck M, Biffar R, Völzke H, Baumeister SE, Wallaschofski H.

Andrology. 2013 Jan;1(1):17-23. doi: 10.1111/j.2047-2927.2012.00002.x. Epub 2012 Aug 26.

9.

The heritability of circulating testosterone, oestradiol, oestrone and sex hormone binding globulin concentrations in men: the Framingham Heart Study.

Travison TG, Zhuang WV, Lunetta KL, Karasik D, Bhasin S, Kiel DP, Coviello AD, Murabito JM.

Clin Endocrinol (Oxf). 2014 Feb;80(2):277-82. doi: 10.1111/cen.12260. Epub 2013 Jun 27.

10.

Association of anthropometric, androgenic and insulin-related features with polymorphisms in exon 8 of SHBG gene in women with polycystic ovary syndrome.

Hacıhanefioğlu B, Aybey B, Hakan Özön Y, Berkil H, Karşıdağ K.

Gynecol Endocrinol. 2013 Apr;29(4):361-4. doi: 10.3109/09513590.2012.743006. Epub 2013 Jan 10.

PMID:
23305451
11.

The relation of smoking, age, relative weight, and dietary intake to serum adrenal steroids, sex hormones, and sex hormone-binding globulin in middle-aged men.

Field AE, Colditz GA, Willett WC, Longcope C, McKinlay JB.

J Clin Endocrinol Metab. 1994 Nov;79(5):1310-6.

PMID:
7962322
12.

SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.

Eriksson AL, Lorentzon M, Mellström D, Vandenput L, Swanson C, Andersson N, Hammond GL, Jakobsson J, Rane A, Orwoll ES, Ljunggren O, Johnell O, Labrie F, Windahl SH, Ohlsson C.

J Clin Endocrinol Metab. 2006 Dec;91(12):5029-37. Epub 2006 Aug 22.

PMID:
16926255
13.
14.
15.

Osteoporosis in men: a potential role for the sex hormone binding globulin.

Legrand E, Hedde C, Gallois Y, Degasne I, Boux de Casson F, Mathieu E, Baslé MF, Chappard D, Audran M.

Bone. 2001 Jul;29(1):90-5.

PMID:
11472897
16.

High serum testosterone is associated with reduced risk of cardiovascular events in elderly men. The MrOS (Osteoporotic Fractures in Men) study in Sweden.

Ohlsson C, Barrett-Connor E, Bhasin S, Orwoll E, Labrie F, Karlsson MK, Ljunggren O, Vandenput L, Mellström D, Tivesten A.

J Am Coll Cardiol. 2011 Oct 11;58(16):1674-81. doi: 10.1016/j.jacc.2011.07.019.

17.

Serum androgen concentrations in young men: a longitudinal analysis of associations with age, obesity, and race. The CARDIA male hormone study.

Gapstur SM, Gann PH, Kopp P, Colangelo L, Longcope C, Liu K.

Cancer Epidemiol Biomarkers Prev. 2002 Oct;11(10 Pt 1):1041-7.

18.

Association between serum levels and pentanucleotide polymorphism in the sex hormone binding globulin gene and cardiovascular risk factors in females with polycystic ovary syndrome.

Baldani DP, Skrgatic L, Cerne JZ, Oguic SK, Gersak BM, Gersak K.

Mol Med Rep. 2015 May;11(5):3941-7. doi: 10.3892/mmr.2014.3117. Epub 2014 Dec 19.

PMID:
25530260
19.

Influence of some biological indexes on sex hormone-binding globulin and androgen levels in aging or obese males.

Vermeulen A, Kaufman JM, Giagulli VA.

J Clin Endocrinol Metab. 1996 May;81(5):1821-6.

PMID:
8626841
20.

Testosterone, sex hormone-binding globulin and the metabolic syndrome in men: an individual participant data meta-analysis of observational studies.

Brand JS, Rovers MM, Yeap BB, Schneider HJ, Tuomainen TP, Haring R, Corona G, Onat A, Maggio M, Bouchard C, Tong PC, Chen RY, Akishita M, Gietema JA, Gannagé-Yared MH, Undén AL, Hautanen A, Goncharov NP, Kumanov P, Chubb SA, Almeida OP, Wittchen HU, Klotsche J, Wallaschofski H, Völzke H, Kauhanen J, Salonen JT, Ferrucci L, van der Schouw YT.

PLoS One. 2014 Jul 14;9(7):e100409. doi: 10.1371/journal.pone.0100409. eCollection 2014.

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