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Items: 1 to 20 of 110

1.

Purified cranberry proanthocyanidines (PAC-1A) cause pro-apoptotic signaling, ROS generation, cyclophosphamide retention and cytotoxicity in high-risk neuroblastoma cells.

Singh AP, Lange TS, Kim KK, Brard L, Horan T, Moore RG, Vorsa N, Singh RK.

Int J Oncol. 2012 Jan;40(1):99-108. doi: 10.3892/ijo.2011.1225. Epub 2011 Oct 6.

PMID:
21994123
2.

Anti-angiogenic activity of cranberry proanthocyanidins and cytotoxic properties in ovarian cancer cells.

Kim KK, Singh AP, Singh RK, Demartino A, Brard L, Vorsa N, Lange TS, Moore RG.

Int J Oncol. 2012 Jan;40(1):227-35. doi: 10.3892/ijo.2011.1198. Epub 2011 Sep 12.

PMID:
21922132
3.

Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation.

Kresty LA, Weh KM, Zeyzus-Johns B, Perez LN, Howell AB.

Oncotarget. 2015 Oct 20;6(32):33438-55. doi: 10.18632/oncotarget.5586.

4.

Oral RKS262 reduces tumor burden in a neuroblastoma xenograft animal model and mediates cytotoxicity through SAPK/JNK and ROS activation in vitro.

Singh RK, Dorf L, DeMartino A, Illenye S, Koto K, Currier EA, Ashikaga T, Kim KK, Brard L, Sholler GL.

Cancer Biol Ther. 2011 Jun 15;11(12):1036-45. Epub 2011 Jun 15.

PMID:
21532338
5.

Cranberry proanthocyanidins induce apoptosis and inhibit acid-induced proliferation of human esophageal adenocarcinoma cells.

Kresty LA, Howell AB, Baird M.

J Agric Food Chem. 2008 Feb 13;56(3):676-80. doi: 10.1021/jf071997t. Epub 2008 Jan 23.

PMID:
18211022
6.

PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis.

Bender A, Opel D, Naumann I, Kappler R, Friedman L, von Schweinitz D, Debatin KM, Fulda S.

Oncogene. 2011 Jan 27;30(4):494-503. doi: 10.1038/onc.2010.429. Epub 2010 Sep 20.

PMID:
20856197
7.
8.
9.

Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.

Calviño E, Estañ MC, Simón GP, Sancho P, Boyano-Adánez Mdel C, de Blas E, Bréard J, Aller P.

Biochem Pharmacol. 2011 Dec 1;82(11):1619-29. doi: 10.1016/j.bcp.2011.08.017. Epub 2011 Aug 27.

PMID:
21889928
10.
11.

Mulberry fruit (Moris fructus) extracts induce human glioma cell death in vitro through ROS-dependent mitochondrial pathway and inhibits glioma tumor growth in vivo.

Jeong JC, Jang SW, Kim TH, Kwon CH, Kim YK.

Nutr Cancer. 2010;62(3):402-12. doi: 10.1080/01635580903441287.

PMID:
20358478
12.

The effect of MAPK inhibitors on arsenic trioxide-treated Calu-6 lung cells in relation to cell death, ROS and GSH levels.

Han YH, Moon HJ, You BR, Kim SZ, Kim SH, Park WH.

Anticancer Res. 2009 Oct;29(10):3837-44.

14.

Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.

Kang MH, Wan Z, Kang YH, Sposto R, Reynolds CP.

J Natl Cancer Inst. 2008 Apr 16;100(8):580-95. doi: 10.1093/jnci/djn076. Epub 2008 Apr 8.

PMID:
18398104
15.

Anti-apoptotic effect of esculin on dopamine-induced cytotoxicity in the human neuroblastoma SH-SY5Y cell line.

Zhao DL, Zou LB, Lin S, Shi JG, Zhu HB.

Neuropharmacology. 2007 Nov;53(6):724-32. Epub 2007 Aug 16.

PMID:
17904593
16.

Luteolin induces apoptosis through endoplasmic reticulum stress and mitochondrial dysfunction in Neuro-2a mouse neuroblastoma cells.

Choi AY, Choi JH, Yoon H, Hwang KY, Noh MH, Choe W, Yoon KS, Ha J, Yeo EJ, Kang I.

Eur J Pharmacol. 2011 Oct 1;668(1-2):115-26. doi: 10.1016/j.ejphar.2011.06.047. Epub 2011 Jul 8.

PMID:
21762691
17.

Tirapazamine cytotoxicity for neuroblastoma is p53 dependent.

Yang B, Reynolds CP.

Clin Cancer Res. 2005 Apr 1;11(7):2774-80.

18.

Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line.

Armstrong JS, Steinauer KK, Hornung B, Irish JM, Lecane P, Birrell GW, Peehl DM, Knox SJ.

Cell Death Differ. 2002 Mar;9(3):252-63.

19.

Induction of apoptosis by vitamin D2, ergocalciferol, via reactive oxygen species generation, glutathione depletion, and caspase activation in human leukemia Cells.

Chen WJ, Huang YT, Wu ML, Huang TC, Ho CT, Pan MH.

J Agric Food Chem. 2008 May 14;56(9):2996-3005. doi: 10.1021/jf0730744. Epub 2008 Apr 3.

PMID:
18386902
20.

Andrographolide induces cell cycle arrest at G2/M phase and cell death in HepG2 cells via alteration of reactive oxygen species.

Li J, Cheung HY, Zhang Z, Chan GK, Fong WF.

Eur J Pharmacol. 2007 Jul 30;568(1-3):31-44. Epub 2007 Apr 22.

PMID:
17512926

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