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Phase II study of the effects of ginger root extract on eicosanoids in colon mucosa in people at normal risk for colorectal cancer.

Zick SM, Turgeon DK, Vareed SK, Ruffin MT, Litzinger AJ, Wright BD, Alrawi S, Normolle DP, Djuric Z, Brenner DE.

Cancer Prev Res (Phila). 2011 Nov;4(11):1929-37. doi: 10.1158/1940-6207.CAPR-11-0224. Epub 2011 Oct 11.


Pilot clinical study of the effects of ginger root extract on eicosanoids in colonic mucosa of subjects at increased risk for colorectal cancer.

Zick SM, Turgeon DK, Ren J, Ruffin MT, Wright BD, Sen A, Djuric Z, Brenner DE.

Mol Carcinog. 2015 Sep;54(9):908-15. doi: 10.1002/mc.22163. Epub 2014 Apr 24.


Effect of ginger root on cyclooxygenase-1 and 15-hydroxyprostaglandin dehydrogenase expression in colonic mucosa of humans at normal and increased risk for colorectal cancer.

Jiang Y, Turgeon DK, Wright BD, Sidahmed E, Ruffin MT, Brenner DE, Sen A, Zick SM.

Eur J Cancer Prev. 2013 Sep;22(5):455-60. doi: 10.1097/CEJ.0b013e32835c829b.


Ultra-pressure liquid chromatography/tandem mass spectrometry targeted profiling of arachidonic acid and eicosanoids in human colorectal cancer.

Mal M, Koh PK, Cheah PY, Chan EC.

Rapid Commun Mass Spectrom. 2011 Mar 30;25(6):755-64. doi: 10.1002/rcm.4926.


Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in mice.

Neilson AP, Djuric Z, Ren J, Hong YH, Sen A, Lager C, Jiang Y, Reuven S, Smith WL, Brenner DE.

J Nutr Biochem. 2012 Aug;23(8):966-76. doi: 10.1016/j.jnutbio.2011.05.003. Epub 2011 Sep 19.


Effect of fish oil on levels of R- and S-enantiomers of 5-, 12-, and 15-hydroxyeicosatetraenoic acids in mouse colonic mucosa.

Neilson AP, Ren J, Hong YH, Sen A, Smith WL, Brenner DE, Djuric Z.

Nutr Cancer. 2012;64(1):163-72. doi: 10.1080/01635581.2012.630168. Epub 2011 Dec 9.


Comparative analysis of peritoneum and tumor eicosanoids and pathways in advanced ovarian cancer.

Freedman RS, Wang E, Voiculescu S, Patenia R, Bassett RL Jr, Deavers M, Marincola FM, Yang P, Newman RA.

Clin Cancer Res. 2007 Oct 1;13(19):5736-44.


15-HETE is the main eicosanoid formed by human colonic mucosa.

Zijlstra FJ, van Dijk AP, Wilson JH, van Riemsdijk-Overbeeke IC, Vincent JE, Ouwendijk RJ.

Agents Actions. 1992;Spec No:C53-9.


Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale).

van Breemen RB, Tao Y, Li W.

Fitoterapia. 2011 Jan;82(1):38-43. doi: 10.1016/j.fitote.2010.09.004. Epub 2010 Sep 15.


Elevated 12- and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases.

Nithipatikom K, Isbell MA, See WA, Campbell WB.

Cancer Lett. 2006 Feb 28;233(2):219-25.


Interleukin-1 increases 15-hydroxyeicosatetraenoic acid production in human dermal fibroblasts.

Godessart N, Vila L, Puig L, de Moragas JM.

J Invest Dermatol. 1994 Jan;102(1):98-104.


Analysis of cytochrome P450 metabolites of arachidonic acid by stable isotope probe labeling coupled with ultra high-performance liquid chromatography/mass spectrometry.

Zhu QF, Hao YH, Liu MZ, Yue J, Ni J, Yuan BF, Feng YQ.

J Chromatogr A. 2015 Sep 4;1410:154-63. doi: 10.1016/j.chroma.2015.07.100. Epub 2015 Jul 29.


Species differences in the pattern of eicosanoids produced by inflamed and non-inflamed tissue.

Zijlstra FJ, van Dijk AP, Garrelds IM, Ouwendijk RJ, Wilson JH.

Agents Actions. 1992;Spec No:C73-5.


Phase IIa clinical trial of curcumin for the prevention of colorectal neoplasia.

Carroll RE, Benya RV, Turgeon DK, Vareed S, Neuman M, Rodriguez L, Kakarala M, Carpenter PM, McLaren C, Meyskens FL Jr, Brenner DE.

Cancer Prev Res (Phila). 2011 Mar;4(3):354-64. doi: 10.1158/1940-6207.CAPR-10-0098. Erratum in: Cancer Prev Res (Phila). 2012 Dec;5(12):1407. Dosage error in article text.


Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients.

Nuñez-Sánchez MA, García-Villalba R, Monedero-Saiz T, García-Talavera NV, Gómez-Sánchez MB, Sánchez-Álvarez C, García-Albert AM, Rodríguez-Gil FJ, Ruiz-Marín M, Pastor-Quirante FA, Martínez-Díaz F, Yáñez-Gascón MJ, González-Sarrías A, Tomás-Barberán FA, Espín JC.

Mol Nutr Food Res. 2014 Jun;58(6):1199-211. doi: 10.1002/mnfr.201300931. Epub 2014 Feb 16.


Eicosanoid profile of healing colon anastomosis and peritoneal macrophages in the rat.

van der Ham AC, Kort WJ, Bijma AM, Zijlstra FJ, Vermeer MA, Jeekel J.

Gut. 1990 Jul;31(7):807-11.


Effects of ginger supplementation on cell-cycle biomarkers in the normal-appearing colonic mucosa of patients at increased risk for colorectal cancer: results from a pilot, randomized, and controlled trial.

Citronberg J, Bostick R, Ahearn T, Turgeon DK, Ruffin MT, Djuric Z, Sen A, Brenner DE, Zick SM.

Cancer Prev Res (Phila). 2013 Apr;6(4):271-81. doi: 10.1158/1940-6207.CAPR-12-0327. Epub 2013 Jan 9.


Variation in concentration and labeling of ginger root dietary supplements.

Schwertner HA, Rios DC, Pascoe JE.

Obstet Gynecol. 2006 Jun;107(6):1337-43.


Regulation of preglomerular microvascular 20-hydroxyeicosatetraenoic acid levels by salt depletion.

Carroll MA, Kemp R, Cheng MK, McGiff JC.

Med Sci Monit. 2001 Jul-Aug;7(4):567-72.


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