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Items: 1 to 20 of 122


Myelin specific cells infiltrate MCAO lesions and exacerbate stroke severity.

Ren X, Akiyoshi K, Grafe MR, Vandenbark AA, Hurn PD, Herson PS, Offner H.

Metab Brain Dis. 2012 Mar;27(1):7-15. doi: 10.1007/s11011-011-9267-5. Epub 2011 Oct 12.


Therapy with recombinant T-cell receptor ligand reduces infarct size and infiltrating inflammatory cells in brain after middle cerebral artery occlusion in mice.

Dziennis S, Mader S, Akiyoshi K, Ren X, Ayala P, Burrows GG, Vandenbark AA, Herson PS, Hurn PD, Offner HA.

Metab Brain Dis. 2011 Jun;26(2):123-33. doi: 10.1007/s11011-011-9241-2. Epub 2011 Apr 7.


Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke.

Römer C, Engel O, Winek K, Hochmeister S, Zhang T, Royl G, Klehmet J, Dirnagl U, Meisel C, Meisel A.

J Neurosci. 2015 May 20;35(20):7777-94. doi: 10.1523/JNEUROSCI.1532-14.2015.


T cell-depleted splenocytes from mice pre-immunized with neuroantigen in incomplete Freund's adjuvant involved in protection from experimental autoimmune encephalomyelitis.

Zheng H, Zhang H, Liu F, Qi Y, Jiang H.

Immunol Lett. 2014 Jan-Feb;157(1-2):38-44. doi: 10.1016/j.imlet.2013.11.001. Epub 2013 Nov 9.


Erythropoietin enhances endogenous haem oxygenase-1 and represses immune responses to ameliorate experimental autoimmune encephalomyelitis.

Chen SJ, Wang YL, Lo WT, Wu CC, Hsieh CW, Huang CF, Lan YH, Wang CC, Chang DM, Sytwu HK.

Clin Exp Immunol. 2010 Nov;162(2):210-23.


Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis.

Domingues HS, Mues M, Lassmann H, Wekerle H, Krishnamoorthy G.

PLoS One. 2010 Nov 29;5(11):e15531. doi: 10.1371/journal.pone.0015531.


T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system.

Linington C, Berger T, Perry L, Weerth S, Hinze-Selch D, Zhang Y, Lu HC, Lassmann H, Wekerle H.

Eur J Immunol. 1993 Jun;23(6):1364-72.


Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes.

Furlan R, Brambilla E, Ruffini F, Poliani PL, Bergami A, Marconi PC, Franciotta DM, Penna G, Comi G, Adorini L, Martino G.

J Immunol. 2001 Aug 1;167(3):1821-9.


Treatment of experimental stroke with IL-10-producing B-cells reduces infarct size and peripheral and CNS inflammation in wild-type B-cell-sufficient mice.

Bodhankar S, Chen Y, Vandenbark AA, Murphy SJ, Offner H.

Metab Brain Dis. 2014 Mar;29(1):59-73. doi: 10.1007/s11011-013-9474-3. Epub 2013 Dec 28.


Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis.

Buhler LA, Samara R, Guzman E, Wilson CL, Krizanac-Bengez L, Janigro D, Ethell DW.

BMC Neurosci. 2009 Mar 6;10:17. doi: 10.1186/1471-2202-10-17.


Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis.

van Zwam M, Huizinga R, Heijmans N, van Meurs M, Wierenga-Wolf AF, Melief MJ, Hintzen RQ, 't Hart BA, Amor S, Boven LA, Laman JD.

J Pathol. 2009 Mar;217(4):543-51. doi: 10.1002/path.2476.


Nasal vaccination with myelin oligodendrocyte glycoprotein reduces stroke size by inducing IL-10-producing CD4+ T cells.

Frenkel D, Huang Z, Maron R, Koldzic DN, Hancock WW, Moskowitz MA, Weiner HL.

J Immunol. 2003 Dec 15;171(12):6549-55.


Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.

Berer K, Mues M, Koutrolos M, Rasbi ZA, Boziki M, Johner C, Wekerle H, Krishnamoorthy G.

Nature. 2011 Oct 26;479(7374):538-41. doi: 10.1038/nature10554.


Autoimmunity against myelin oligodendrocyte glycoprotein is dispensable for the initiation although essential for the progression of chronic encephalomyelitis in common marmosets.

Jagessar SA, Smith PA, Blezer E, Delarasse C, Pham-Dinh D, Laman JD, Bauer J, Amor S, 't Hart B.

J Neuropathol Exp Neurol. 2008 Apr;67(4):326-40. doi: 10.1097/NEN.0b013e31816a6851.


Chemokine-like receptor-1 expression by central nervous system-infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease.

Graham KL, Zabel BA, Loghavi S, Zuniga LA, Ho PP, Sobel RA, Butcher EC.

J Immunol. 2009 Nov 15;183(10):6717-23. doi: 10.4049/jimmunol.0803435. Epub 2009 Oct 28.


Role of dihydrotestosterone in post-stroke peripheral immunosuppression after cerebral ischemia.

Dziennis S, Akiyoshi K, Subramanian S, Offner H, Hurn PD.

Brain Behav Immun. 2011 May;25(4):685-95. doi: 10.1016/j.bbi.2011.01.009. Epub 2011 Jan 22.


T cells become licensed in the lung to enter the central nervous system.

Odoardi F, Sie C, Streyl K, Ulaganathan VK, Schläger C, Lodygin D, Heckelsmiller K, Nietfeld W, Ellwart J, Klinkert WE, Lottaz C, Nosov M, Brinkmann V, Spang R, Lehrach H, Vingron M, Wekerle H, Flügel-Koch C, Flügel A.

Nature. 2012 Aug 30;488(7413):675-9. doi: 10.1038/nature11337.


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