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Items: 1 to 20 of 88

1.

Effects of solution concentration on the physicochemical properties of a polymeric anticancer therapeutic.

Peng LX, Yu L, Howell SB, Gough DA.

Mol Pharm. 2012 Jan 1;9(1):37-47. doi: 10.1021/mp2002208. Epub 2011 Nov 22.

PMID:
21988542
2.

Aggregation properties of a polymeric anticancer therapeutic: a coarse-grained modeling study.

Peng LX, Yu L, Howell SB, Gough DA.

J Chem Inf Model. 2011 Dec 27;51(12):3030-5. doi: 10.1021/ci200214m. Epub 2011 Nov 21.

PMID:
21995420
3.

Characterization of a clinical polymer-drug conjugate using multiscale modeling.

Peng LX, Ivetac A, Chaudhari AS, Van S, Zhao G, Yu L, Howell SB, McCammon JA, Gough DA.

Biopolymers. 2010 Nov;93(11):936-51. doi: 10.1002/bip.21474.

4.

Coarse-grained modeling study of nonpeptide RGD ligand density and PEG molecular weight on the conformation of poly(γ-glutamyl-glutamate) paclitaxel conjugates.

Peng LX, Das SK, Yu L, Howell SB, Gough DA.

J Mol Model. 2011 Nov;17(11):2973-87. doi: 10.1007/s00894-011-0989-4. Epub 2011 Mar 1.

5.

Synthesis, characterization, and biological evaluation of poly(L-γ-glutamyl-glutamine)- paclitaxel nanoconjugate.

Van S, Das SK, Wang X, Feng Z, Jin Y, Hou Z, Chen F, Pham A, Jiang N, Howell SB, Yu L.

Int J Nanomedicine. 2010 Oct 21;5:825-37. doi: 10.2147/IJN.S13482.

6.

Physicochemical properties and biocompatibility of a polymer-paclitaxel conjugate for cancer treatment.

Yang D, Van S, Liu J, Wang J, Jiang X, Wang Y, Yu L.

Int J Nanomedicine. 2011;6:2557-66. doi: 10.2147/IJN.S25044. Epub 2011 Oct 21.

7.

Precise glioblastoma targeting by AS1411 aptamer-functionalized poly (l-γ-glutamylglutamine)-paclitaxel nanoconjugates.

Luo Z, Yan Z, Jin K, Pang Q, Jiang T, Lu H, Liu X, Pang Z, Yu L, Jiang X.

J Colloid Interface Sci. 2017 Mar 15;490:783-796. doi: 10.1016/j.jcis.2016.12.004. Epub 2016 Dec 7.

PMID:
27988470
8.

Preclinical efficacy studies of a novel nanoparticle-based formulation of paclitaxel that out-performs Abraxane.

Feng Z, Zhao G, Yu L, Gough D, Howell SB.

Cancer Chemother Pharmacol. 2010 Apr;65(5):923-30. doi: 10.1007/s00280-009-1099-1. Epub 2009 Aug 15.

9.

Pharmacokinetics and tissue distribution of PGG-paclitaxel, a novel macromolecular formulation of paclitaxel, in nu/nu mice bearing NCI-460 lung cancer xenografts.

Wang X, Zhao G, Van S, Jiang N, Yu L, Vera D, Howell SB.

Cancer Chemother Pharmacol. 2010 Feb;65(3):515-26. doi: 10.1007/s00280-009-1058-x. Epub 2009 Jul 11.

10.

Novel free paclitaxel-loaded poly(L-γ-glutamylglutamine)-paclitaxel nanoparticles.

Yang D, Van S, Jiang X, Yu L.

Int J Nanomedicine. 2011 Jan 6;6:85-91. doi: 10.2147/IJN.S15839.

11.

Paclitaxel isomerisation in polymeric micelles based on hydrophobized hyaluronic acid.

Smejkalová D, Nešporová K, Hermannová M, Huerta-Angeles G, Cožíková D, Vištejnová L, Safránková B, Novotný J, Kučerík J, Velebný V.

Int J Pharm. 2014 May 15;466(1-2):147-55. doi: 10.1016/j.ijpharm.2014.03.024. Epub 2014 Mar 11.

PMID:
24614580
12.

Paclitaxel loaded folic acid targeted nanoparticles of mixed lipid-shell and polymer-core: in vitro and in vivo evaluation.

Zhao P, Wang H, Yu M, Liao Z, Wang X, Zhang F, Ji W, Wu B, Han J, Zhang H, Wang H, Chang J, Niu R.

Eur J Pharm Biopharm. 2012 Jun;81(2):248-56. doi: 10.1016/j.ejpb.2012.03.004. Epub 2012 Mar 14.

PMID:
22446630
13.

Thermosensitive and biodegradable polymeric micelles for paclitaxel delivery.

Soga O, van Nostrum CF, Fens M, Rijcken CJ, Schiffelers RM, Storm G, Hennink WE.

J Control Release. 2005 Mar 21;103(2):341-53.

PMID:
15763618
14.

Dual targeting folate-conjugated hyaluronic acid polymeric micelles for paclitaxel delivery.

Liu Y, Sun J, Cao W, Yang J, Lian H, Li X, Sun Y, Wang Y, Wang S, He Z.

Int J Pharm. 2011 Dec 12;421(1):160-9. doi: 10.1016/j.ijpharm.2011.09.006. Epub 2011 Sep 16.

PMID:
21945183
15.

Effect of molecular weight of PGG-paclitaxel conjugates on in vitro and in vivo efficacy.

Yang D, Liu X, Jiang X, Liu Y, Ying W, Wang H, Bai H, Taylor WD, Wang Y, Clamme JP, Co E, Chivukula P, Tsang KY, Jin Y, Yu L.

J Control Release. 2012 Jul 10;161(1):124-31. doi: 10.1016/j.jconrel.2012.04.010. Epub 2012 Apr 12.

PMID:
22521595
16.

Construction of polymer-paclitaxel conjugate linked via a disulfide bond.

Yan Q, Yang Y, Chen W, Hu J, Yang D.

Mater Sci Eng C Mater Biol Appl. 2016 Jan 1;58:580-5. doi: 10.1016/j.msec.2015.09.025. Epub 2015 Sep 10.

PMID:
26478347
17.

Polymeric complex micelles with double drug-loading strategies for folate-mediated paclitaxel delivery.

Li M, Liu Y, Feng L, Liu F, Zhang L, Zhang N.

Colloids Surf B Biointerfaces. 2015 Jul 1;131:191-201. doi: 10.1016/j.colsurfb.2015.04.057. Epub 2015 May 5.

PMID:
25988283
18.

Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles.

Shi Y, van der Meel R, Theek B, Oude Blenke E, Pieters EH, Fens MH, Ehling J, Schiffelers RM, Storm G, van Nostrum CF, Lammers T, Hennink WE.

ACS Nano. 2015;9(4):3740-52. doi: 10.1021/acsnano.5b00929. Epub 2015 Apr 6.

19.

Paclitaxel loaded nano-aggregates based on pH sensitive polyaspartamide amphiphilic graft copolymers.

Seo K, Chung SW, Byun Y, Kim D.

Int J Pharm. 2012 Mar 15;424(1-2):26-32. doi: 10.1016/j.ijpharm.2011.12.047. Epub 2011 Dec 31.

PMID:
22226879
20.

Synthesis and optimization of a novel polymeric micelle based on hyaluronic acid and phospholipids for delivery of paclitaxel, in vitro and in-vivo evaluation.

Saadat E, Amini M, Khoshayand MR, Dinarvand R, Dorkoosh FA.

Int J Pharm. 2014 Nov 20;475(1-2):163-73. doi: 10.1016/j.ijpharm.2014.08.030. Epub 2014 Aug 20.

PMID:
25148729

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