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The Ebolavirus VP24 protein blocks phosphorylation of p38 mitogen-activated protein kinase.

Halfmann P, Neumann G, Kawaoka Y.

J Infect Dis. 2011 Nov;204 Suppl 3:S953-6. doi: 10.1093/infdis/jir325.


Inhibition of p38 mitogen-activated protein kinase impairs influenza virus-induced primary and secondary host gene responses and protects mice from lethal H5N1 infection.

Börgeling Y, Schmolke M, Viemann D, Nordhoff C, Roth J, Ludwig S.

J Biol Chem. 2014 Jan 3;289(1):13-27. doi: 10.1074/jbc.M113.469239. Epub 2013 Nov 4.


Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling.

Mateo M, Reid SP, Leung LW, Basler CF, Volchkov VE.

J Virol. 2010 Jan;84(2):1169-75. doi: 10.1128/JVI.01372-09. Epub 2009 Nov 4.


Multiple anti-apoptotic pathways stimulated by EGF in cytotrophoblasts.

Johnstone ED, Mackova M, Das S, Payne SG, Lowen B, Sibley CP, Chan G, Guilbert LJ.

Placenta. 2005 Aug;26(7):548-55.


Roles of phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase in the regulation of protein kinase C-alpha activation in interferon-gamma-stimulated macrophages.

Hardy PO, Diallo TO, Matte C, Descoteaux A.

Immunology. 2009 Sep;128(1 Suppl):e652-60. doi: 10.1111/j.1365-2567.2009.03055.x. Epub 2009 Jan 23.


Activation of the p38 mitogen-activated protein kinase mediates the suppressive effects of type I interferons and transforming growth factor-beta on normal hematopoiesis.

Verma A, Deb DK, Sassano A, Uddin S, Varga J, Wickrema A, Platanias LC.

J Biol Chem. 2002 Mar 8;277(10):7726-35. Epub 2001 Dec 31.


IKappaB-kinase/nuclear factor-kappaB signaling prevents thermal injury-induced gut damage by inhibiting c-Jun NH2-terminal kinase activation.

Chen LW, Chen PH, Chang WJ, Wang JS, Karin M, Hsu CM.

Crit Care Med. 2007 May;35(5):1332-40.


Interferon-alpha inhibits glucocorticoid receptor-mediated gene transcription via STAT5 activation in mouse HT22 cells.

Hu F, Pace TW, Miller AH.

Brain Behav Immun. 2009 May;23(4):455-63. doi: 10.1016/j.bbi.2009.01.001. Epub 2009 Jan 8.


The role of p38 MAP kinase and c-Jun N-terminal protein kinase signaling in the differentiation and apoptosis of immortalized neural stem cells.

Yang SR, Cho SD, Ahn NS, Jung JW, Park JS, Jo EH, Hwang JW, Kim SH, Lee BH, Kang KS, Lee YS.

Mutat Res. 2005 Nov 11;579(1-2):47-57. Epub 2005 Jul 25.


Activation of c-Jun N-terminal kinase (JNK) by widely used specific p38 MAPK inhibitors SB202190 and SB203580: a MLK-3-MKK7-dependent mechanism.

Muniyappa H, Das KC.

Cell Signal. 2008 Apr;20(4):675-83. doi: 10.1016/j.cellsig.2007.12.003. Epub 2007 Dec 8.


Helicobacter pylori VacA activates the p38/activating transcription factor 2-mediated signal pathway in AZ-521 cells.

Nakayama M, Kimura M, Wada A, Yahiro K, Ogushi K, Niidome T, Fujikawa A, Shirasaka D, Aoyama N, Kurazono H, Noda M, Moss J, Hirayama T.

J Biol Chem. 2004 Feb 20;279(8):7024-8. Epub 2003 Nov 20.


Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.

Kovarik P, Stoiber D, Eyers PA, Menghini R, Neininger A, Gaestel M, Cohen P, Decker T.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13956-61.


Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells.

Wang SF, Yen JC, Yin PH, Chi CW, Lee HC.

Toxicology. 2008 Apr 18;246(2-3):234-41. doi: 10.1016/j.tox.2008.01.020. Epub 2008 Feb 6.


The Rac1/p38 mitogen-activated protein kinase pathway is required for interferon alpha-dependent transcriptional activation but not serine phosphorylation of Stat proteins.

Uddin S, Lekmine F, Sharma N, Majchrzak B, Mayer I, Young PR, Bokoch GM, Fish EN, Platanias LC.

J Biol Chem. 2000 Sep 8;275(36):27634-40.


Genistein inhibits cell growth by modulating various mitogen-activated protein kinases and AKT in cervical cancer cells.

Kim SH, Kim SH, Kim YB, Jeon YT, Lee SC, Song YS.

Ann N Y Acad Sci. 2009 Aug;1171:495-500. doi: 10.1111/j.1749-6632.2009.04899.x.


Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration.

Tsai HR, Yang LM, Tsai WJ, Chiou WF.

Eur J Pharmacol. 2004 Sep 13;498(1-3):45-52.


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