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Items: 1 to 20 of 116

1.

The Ebola virus VP24 protein prevents hnRNP C1/C2 binding to karyopherin α1 and partially alters its nuclear import.

Shabman RS, Gulcicek EE, Stone KL, Basler CF.

J Infect Dis. 2011 Nov;204 Suppl 3:S904-10. doi: 10.1093/infdis/jir323.

2.

VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability.

Schwarz TM, Edwards MR, Diederichs A, Alinger JB, Leung DW, Amarasinghe GK, Basler CF.

J Virol. 2017 Jan 31;91(4). pii: e01715-16. doi: 10.1128/JVI.01715-16. Print 2017 Feb 15.

3.

Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.

Reid SP, Valmas C, Martinez O, Sanchez FM, Basler CF.

J Virol. 2007 Dec;81(24):13469-77. Epub 2007 Oct 10.

4.

Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling.

Mateo M, Reid SP, Leung LW, Basler CF, Volchkov VE.

J Virol. 2010 Jan;84(2):1169-75. doi: 10.1128/JVI.01372-09. Epub 2009 Nov 4.

5.

Ebola virus VP24 binds karyopherin alpha1 and blocks STAT1 nuclear accumulation.

Reid SP, Leung LW, Hartman AL, Martinez O, Shaw ML, Carbonnelle C, Volchkov VE, Nichol ST, Basler CF.

J Virol. 2006 Jun;80(11):5156-67.

6.

Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1.

Xu W, Edwards MR, Borek DM, Feagins AR, Mittal A, Alinger JB, Berry KN, Yen B, Hamilton J, Brett TJ, Pappu RV, Leung DW, Basler CF, Amarasinghe GK.

Cell Host Microbe. 2014 Aug 13;16(2):187-200. doi: 10.1016/j.chom.2014.07.008.

7.

Evasion of interferon responses by Ebola and Marburg viruses.

Basler CF, Amarasinghe GK.

J Interferon Cytokine Res. 2009 Sep;29(9):511-20. doi: 10.1089/jir.2009.0076. Review.

8.

Regulation of karyopherin α1 and nuclear import by mammalian target of rapamycin.

Fielhaber JA, Tan J, Joung KB, Attias O, Huegel S, Bader M, Roux PP, Kristof AS.

J Biol Chem. 2012 Apr 27;287(18):14325-35. doi: 10.1074/jbc.M111.246785. Epub 2012 Mar 6.

9.

Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane.

Frieman M, Yount B, Heise M, Kopecky-Bromberg SA, Palese P, Baric RS.

J Virol. 2007 Sep;81(18):9812-24. Epub 2007 Jun 27.

10.

Nuclear efflux of heterogeneous nuclear ribonucleoprotein C1/C2 in apoptotic cells: a novel nuclear export dependent on Rho-associated kinase activation.

Lee HH, Chien CL, Liao HK, Chen YJ, Chang ZF.

J Cell Sci. 2004 Nov 1;117(Pt 23):5579-89. Epub 2004 Oct 19.

11.

An all-atom molecular dynamics study of the anti-interferon signaling of Ebola virus: interaction mechanisms of EBOV VP24 binding to Karyopherin alpha5.

Ding JN, Zhang YJ, Zhong H, Ao CC, Li J, Han JG.

Mol Biosyst. 2017 May 2;13(5):1031-1045. doi: 10.1039/c7mb00136c.

PMID:
28418440
12.

The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold.

Zhang AP, Bornholdt ZA, Liu T, Abelson DM, Lee DE, Li S, Woods VL Jr, Saphire EO.

PLoS Pathog. 2012 Feb;8(2):e1002550. doi: 10.1371/journal.ppat.1002550. Epub 2012 Feb 23. Erratum in: PLoS Pathog. 2013 Dec;9(12). doi:10.1371/annotation/360ddc68-0313-4eae-af24-043cc040c52d.

13.

Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells.

Feagins AR, Basler CF.

Virology. 2015 Nov;485:145-52. doi: 10.1016/j.virol.2015.07.010. Epub 2015 Aug 6.

14.

Role of human heterogeneous nuclear ribonucleoprotein C1/C2 in dengue virus replication.

Dechtawewat T, Songprakhon P, Limjindaporn T, Puttikhunt C, Kasinrerk W, Saitornuang S, Yenchitsomanus PT, Noisakran S.

Virol J. 2015 Feb 6;12:14. doi: 10.1186/s12985-014-0219-7.

15.

Knockdown of Ebola virus VP24 impairs viral nucleocapsid assembly and prevents virus replication.

Mateo M, Carbonnelle C, Martinez MJ, Reynard O, Page A, Volchkova VA, Volchkov VE.

J Infect Dis. 2011 Nov;204 Suppl 3:S892-6. doi: 10.1093/infdis/jir311.

PMID:
21987766
16.
17.

Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.

Choo HJ, Cutler A, Rother F, Bader M, Pavlath GK.

Stem Cells. 2016 Nov;34(11):2784-2797. doi: 10.1002/stem.2467. Epub 2016 Aug 1.

18.

In Silico Study of Plant Polyphenols' Interactions with VP24-Ebola Virus Membrane-associated Protein.

Pleško S, Volk H, Lukšič M, Podlipnik Č.

Acta Chim Slov. 2015;62(3):555-64.

PMID:
26454589
19.

Functional interaction of heterogeneous nuclear ribonucleoprotein C with poliovirus RNA synthesis initiation complexes.

Brunner JE, Nguyen JH, Roehl HH, Ho TV, Swiderek KM, Semler BL.

J Virol. 2005 Mar;79(6):3254-66.

20.

Importin-α7 Is Involved in the Formation of Ebola Virus Inclusion Bodies but Is Not Essential for Pathogenicity in Mice.

Gabriel G, Feldmann F, Reimer R, Thiele S, Fischer M, Hartmann E, Bader M, Ebihara H, Hoenen T, Feldmann H.

J Infect Dis. 2015 Oct 1;212 Suppl 2:S316-21. doi: 10.1093/infdis/jiv240. Epub 2015 Jul 16.

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