Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 359


Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3.

Gordon J, Hwang J, Carrier KJ, Jones CA, Kern QL, Moreno CS, Karas RH, Pallas DC.

BMC Biochem. 2011 Oct 10;12:54. doi: 10.1186/1471-2091-12-54.


STRIPAK complexes: structure, biological function, and involvement in human diseases.

Hwang J, Pallas DC.

Int J Biochem Cell Biol. 2014 Feb;47:118-48. doi: 10.1016/j.biocel.2013.11.021. Review.


Striatins contain a noncanonical coiled coil that binds protein phosphatase 2A A subunit to form a 2:2 heterotetrameric core of striatin-interacting phosphatase and kinase (STRIPAK) complex.

Chen C, Shi Z, Zhang W, Chen M, He F, Zhang Z, Wang Y, Feng M, Wang W, Zhao Y, Brown JH, Jiao S, Zhou Z.

J Biol Chem. 2014 Apr 4;289(14):9651-61. doi: 10.1074/jbc.M113.529297.


Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization.

Kean MJ, Ceccarelli DF, Goudreault M, Sanches M, Tate S, Larsen B, Gibson LC, Derry WB, Scott IC, Pelletier L, Baillie GS, Sicheri F, Gingras AC.

J Biol Chem. 2011 Jul 15;286(28):25065-75. doi: 10.1074/jbc.M110.214486.


A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.

Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC.

Mol Cell Proteomics. 2009 Jan;8(1):157-71. doi: 10.1074/mcp.M800266-MCP200.


Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

Voss K, Stahl S, Hogan BM, Reinders J, Schleider E, Schulte-Merker S, Felbor U.

Hum Mutat. 2009 Jun;30(6):1003-11. doi: 10.1002/humu.20996.


Structural mechanism of CCM3 heterodimerization with GCKIII kinases.

Zhang M, Dong L, Shi Z, Jiao S, Zhang Z, Zhang W, Liu G, Chen C, Feng M, Hao Q, Wang W, Yin M, Zhao Y, Zhang L, Zhou Z.

Structure. 2013 Apr 2;21(4):680-8.


SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.

Sugden PH, McGuffin LJ, Clerk A.

Biochem J. 2013 Aug 15;454(1):13-30. doi: 10.1042/BJ20130219. Review.


A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3).

Fuller SJ, McGuffin LJ, Marshall AK, Giraldo A, Pikkarainen S, Clerk A, Sugden PH.

Biochem J. 2012 Mar 15;442(3):595-610. doi: 10.1042/BJ20112000.


Downregulation of striatin leads to hyperphosphorylation of MAP2, induces depolymerization of microtubules and inhibits proliferation of HEK293T cells.

Kaźmierczak-Barańska J, Pęczek Ł, Przygodzka P, Cieślak MJ.

FEBS Lett. 2015 Jan 16;589(2):222-30. doi: 10.1016/j.febslet.2014.12.003.


CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations.

Voss K, Stahl S, Schleider E, Ullrich S, Nickel J, Mueller TD, Felbor U.

Neurogenetics. 2007 Nov;8(4):249-56.


CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations.

Zheng X, Xu C, Di Lorenzo A, Kleaveland B, Zou Z, Seiler C, Chen M, Cheng L, Xiao J, He J, Pack MA, Sessa WC, Kahn ML.

J Clin Invest. 2010 Aug;120(8):2795-804. doi: 10.1172/JCI39679.


Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis.

Hyodo T, Ito S, Hasegawa H, Asano E, Maeda M, Urano T, Takahashi M, Hamaguchi M, Senga T.

J Biol Chem. 2012 Jul 20;287(30):25019-29. doi: 10.1074/jbc.M112.372342.


Among the three striatin family members, SG2NA was first to arise during evolution.

Tanti GK, Singarapu N, Muthuswami R, Goswami SK.

Front Biosci (Schol Ed). 2014 Jan 1;6:1-15.


CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization.

Ceccarelli DF, Laister RC, Mulligan VK, Kean MJ, Goudreault M, Scott IC, Derry WB, Chakrabartty A, Gingras AC, Sicheri F.

J Biol Chem. 2011 Jul 15;286(28):25056-64. doi: 10.1074/jbc.M110.213777.


Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

Couzens AL, Knight JD, Kean MJ, Teo G, Weiss A, Dunham WH, Lin ZY, Bagshaw RD, Sicheri F, Pawson T, Wrana JL, Choi H, Gingras AC.

Sci Signal. 2013 Nov 19;6(302):rs15. doi: 10.1126/scisignal.2004712.


Supplemental Content

Support Center