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Items: 1 to 20 of 77

1.

Hydrophobicity profiles in G protein-coupled receptor transmembrane helical domains.

Crasto CJ.

J Receptor Ligand Channel Res. 2010;2010(3):123-133.

2.

Modelling the structures of G protein-coupled receptors aided by three-dimensional validation.

Dastmalchi S, Church WB, Morris MB.

BMC Bioinformatics. 2008;9 Suppl 1:S14. doi: 10.1186/1471-2105-9-S1-S14.

4.

X-ray structure breakthroughs in the GPCR transmembrane region.

Topiol S, Sabio M.

Biochem Pharmacol. 2009 Jul 1;78(1):11-20. doi: 10.1016/j.bcp.2009.02.012. Epub 2009 Feb 27. Review.

PMID:
19447219
5.

Identifying interactions between transmembrane helices from the adenosine A2A receptor.

Thévenin D, Roberts MF, Lazarova T, Robinson CR.

Biochemistry. 2005 Dec 13;44(49):16239-45.

PMID:
16331984
6.

Cholesterol modulates the membrane effects and spatial organization of membrane-penetrating ligands for G-protein coupled receptors.

Khelashvili G, Mondal S, Andersen OS, Weinstein H.

J Phys Chem B. 2010 Sep 23;114(37):12046-57. doi: 10.1021/jp106373r.

7.

Helix packing moments reveal diversity and conservation in membrane protein structure.

Liu W, Eilers M, Patel AB, Smith SO.

J Mol Biol. 2004 Mar 26;337(3):713-29.

PMID:
15019789
9.

Structure-Based Sequence Alignment of the Transmembrane Domains of All Human GPCRs: Phylogenetic, Structural and Functional Implications.

Cvicek V, Goddard WA 3rd, Abrol R.

PLoS Comput Biol. 2016 Mar 30;12(3):e1004805. doi: 10.1371/journal.pcbi.1004805. eCollection 2016 Mar.

10.

G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a survey.

Kratochwil NA, Gatti-McArthur S, Hoener MC, Lindemann L, Christ AD, Green LG, Guba W, Martin RE, Malherbe P, Porter RH, Slack JP, Winnig M, Dehmlow H, Grether U, Hertel C, Narquizian R, Panousis CG, Kolczewski S, Steward L.

Curr Top Med Chem. 2011;11(15):1902-24.

PMID:
21470172
11.

Structure prediction of G protein-coupled receptors and their ensemble of functionally important conformations.

Abrol R, Griffith AR, Bray JK, Goddard WA 3rd.

Methods Mol Biol. 2012;914:237-54. doi: 10.1007/978-1-62703-023-6_14.

PMID:
22976032
12.

Quantification of structural distortions in the transmembrane helices of GPCRs.

Deupi X.

Methods Mol Biol. 2012;914:219-35. doi: 10.1007/978-1-62703-023-6_13.

PMID:
22976031
13.

Relevance of rhodopsin studies for GPCR activation.

Deupi X.

Biochim Biophys Acta. 2014 May;1837(5):674-82. doi: 10.1016/j.bbabio.2013.09.002. Epub 2013 Sep 13. Review.

14.

Structure and dynamics of G-protein coupled receptors.

Vaidehi N, Bhattacharya S, Larsen AB.

Adv Exp Med Biol. 2014;796:37-54. doi: 10.1007/978-94-007-7423-0_3. Review.

PMID:
24158800
15.

Structured and disordered facets of the GPCR fold.

Venkatakrishnan AJ, Flock T, Prado DE, Oates ME, Gough J, Madan Babu M.

Curr Opin Struct Biol. 2014 Aug;27:129-37. doi: 10.1016/j.sbi.2014.08.002. Epub 2014 Sep 3. Review.

PMID:
25198166
16.
17.

Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.

Huber T, Menon S, Sakmar TP.

Biochemistry. 2008 Oct 21;47(42):11013-23. doi: 10.1021/bi800891r. Epub 2008 Sep 27.

PMID:
18821775
18.

FoldGPCR: structure prediction protocol for the transmembrane domain of G protein-coupled receptors from class A.

Michino M, Chen J, Stevens RC, Brooks CL 3rd.

Proteins. 2010 Aug 1;78(10):2189-201. doi: 10.1002/prot.22731.

19.

Endogenous lipid activated G protein-coupled receptors: emerging structural features from crystallography and molecular dynamics simulations.

Hurst DP, Schmeisser M, Reggio PH.

Chem Phys Lipids. 2013 Apr;169:46-56. doi: 10.1016/j.chemphyslip.2013.01.009. Epub 2013 Feb 26. Review.

20.

Chemogenomic analysis of G-protein coupled receptors and their ligands deciphers locks and keys governing diverse aspects of signalling.

Wichard JD, Ter Laak A, Krause G, Heinrich N, Kühne R, Kleinau G.

PLoS One. 2011 Feb 4;6(2):e16811. doi: 10.1371/journal.pone.0016811.

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