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Items: 1 to 20 of 110


A Pre-mRNA degradation pathway that selectively targets intron-containing genes requires the nuclear poly(A)-binding protein.

Lemieux C, Marguerat S, Lafontaine J, Barbezier N, Bähler J, Bachand F.

Mol Cell. 2011 Oct 7;44(1):108-19. doi: 10.1016/j.molcel.2011.06.035.


Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs.

Lemieux C, Bachand F.

Nucleic Acids Res. 2009 Jun;37(10):3418-30. doi: 10.1093/nar/gkp207. Epub 2009 Mar 31.


Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay.

Grenier St-Sauveur V, Soucek S, Corbett AH, Bachand F.

Mol Cell Biol. 2013 Dec;33(23):4718-31. doi: 10.1128/MCB.00887-13. Epub 2013 Sep 30.


Identification of a regulated pathway for nuclear pre-mRNA turnover.

Bousquet-Antonelli C, Presutti C, Tollervey D.

Cell. 2000 Sep 15;102(6):765-75.


The nuclear poly(A)-binding protein interacts with the exosome to promote synthesis of noncoding small nucleolar RNAs.

Lemay JF, D'Amours A, Lemieux C, Lackner DH, St-Sauveur VG, Bähler J, Bachand F.

Mol Cell. 2010 Jan 15;37(1):34-45. doi: 10.1016/j.molcel.2009.12.019. Erratum in: Mol Cell. 2010 Feb 12;37(3):447.


The fission yeast RNA binding protein Mmi1 regulates meiotic genes by controlling intron specific splicing and polyadenylation coupled RNA turnover.

Chen HM, Futcher B, Leatherwood J.

PLoS One. 2011;6(10):e26804. doi: 10.1371/journal.pone.0026804. Epub 2011 Oct 27.


Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1.

Kilchert C, Wittmann S, Passoni M, Shah S, Granneman S, Vasiljeva L.

Cell Rep. 2015 Dec 22;13(11):2504-15. doi: 10.1016/j.celrep.2015.11.026. Epub 2015 Dec 6.


Negative regulation of meiotic gene expression by the nuclear poly(a)-binding protein in fission yeast.

St-André O, Lemieux C, Perreault A, Lackner DH, Bähler J, Bachand F.

J Biol Chem. 2010 Sep 3;285(36):27859-68. doi: 10.1074/jbc.M110.150748. Epub 2010 Jul 9.


Autoregulation of the mRNA export factor Yra1p requires inefficient splicing of its pre-mRNA.

Preker PJ, Guthrie C.

RNA. 2006 Jun;12(6):994-1006. Epub 2006 Apr 17.


A subset of Mer1p-dependent introns requires Bud13p for splicing activation and nuclear retention.

Scherrer FW Jr, Spingola M.

RNA. 2006 Jul;12(7):1361-72. Epub 2006 May 31.


Plant pre-mRNA splicing in fission yeast, Schizosaccharomyces pombe.

Sarmah B, Chakraborty N, Chakraborty S, Datta A.

Biochem Biophys Res Commun. 2002 May 17;293(4):1209-16.


Molecular dissection of mRNA poly(A) tail length control in yeast.

Viphakone N, Voisinet-Hakil F, Minvielle-Sebastia L.

Nucleic Acids Res. 2008 Apr;36(7):2418-33. doi: 10.1093/nar/gkn080. Epub 2008 Feb 26.


Rat1p and Rai1p function with the nuclear exosome in the processing and degradation of rRNA precursors.

Fang F, Phillips S, Butler JS.

RNA. 2005 Oct;11(10):1571-8. Epub 2005 Aug 30.


RNA-RNA interactions and pre-mRNA mislocalization as drivers of group II intron loss from nuclear genomes.

Qu G, Dong X, Piazza CL, Chalamcharla VR, Lutz S, Curcio MJ, Belfort M.

Proc Natl Acad Sci U S A. 2014 May 6;111(18):6612-7. doi: 10.1073/pnas.1404276111. Epub 2014 Apr 10.


Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

Galy V, Gadal O, Fromont-Racine M, Romano A, Jacquier A, Nehrbass U.

Cell. 2004 Jan 9;116(1):63-73.


The pre-mRNA retention and splicing complex controls tRNA maturation by promoting TAN1 expression.

Zhou Y, Chen C, Johansson MJ.

Nucleic Acids Res. 2013 Jun;41(11):5669-78. doi: 10.1093/nar/gkt269. Epub 2013 Apr 19.

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