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Items: 1 to 20 of 99

1.

Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord.

Miller LK, Hou X, Rodriguiz RM, Gagnidze K, Sweedler JV, Wetsel WC, Devi LA.

J Neurochem. 2011 Dec;119(5):1074-85. doi: 10.1111/j.1471-4159.2011.07513.x. Epub 2011 Nov 1.

2.

Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides.

Mzhavia N, Pan H, Che FY, Fricker LD, Devi LA.

J Biol Chem. 2003 Apr 25;278(17):14704-11. Epub 2003 Jan 30.

3.

Endothelin converting enzyme-2: a processing enzyme involved in the generation of novel neuropeptides.

Pan H, Mzhavia N, Devi LA.

Protein Pept Lett. 2004 Oct;11(5):461-9. Review.

PMID:
15544567
4.

Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory.

Rodriguiz RM, Gadnidze K, Ragnauth A, Dorr N, Yanagisawa M, Wetsel WC, Devi LA.

Genes Brain Behav. 2008 Jun;7(4):418-26. doi: 10.1111/j.1601-183X.2007.00365.x.

5.

Attenuation of Doxorubicin-induced cardiomyopathy by endothelin-converting enzyme-1 ablation through prevention of mitochondrial biogenesis impairment.

Miyagawa K, Emoto N, Widyantoro B, Nakayama K, Yagi K, Rikitake Y, Suzuki T, Hirata K.

Hypertension. 2010 Mar;55(3):738-46. doi: 10.1161/HYPERTENSIONAHA.109.141903. Epub 2010 Jan 25.

6.

Enhanced spinal nociceptin receptor expression develops morphine tolerance and dependence.

Ueda H, Inoue M, Takeshima H, Iwasawa Y.

J Neurosci. 2000 Oct 15;20(20):7640-7.

7.

Opioid receptor function is regulated by post-endocytic peptide processing.

Gupta A, Gomes I, Wardman J, Devi LA.

J Biol Chem. 2014 Jul 11;289(28):19613-26. doi: 10.1074/jbc.M113.537704. Epub 2014 May 20.

8.

Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus.

Kido-Nakahara M, Buddenkotte J, Kempkes C, Ikoma A, Cevikbas F, Akiyama T, Nunes F, Seeliger S, Hasdemir B, Mess C, Buhl T, Sulk M, Müller FU, Metze D, Bunnett NW, Bhargava A, Carstens E, Furue M, Steinhoff M.

J Clin Invest. 2014 Jun;124(6):2683-95. doi: 10.1172/JCI67323. Epub 2014 May 8.

9.

Endothelin-converting enzyme-1 gene ablation attenuates pulmonary fibrosis via CGRP-cAMP/EPAC1 pathway.

Hartopo AB, Emoto N, Vignon-Zellweger N, Suzuki Y, Yagi K, Nakayama K, Hirata K.

Am J Respir Cell Mol Biol. 2013 Apr;48(4):465-76. doi: 10.1165/rcmb.2012-0354OC.

PMID:
23306833
10.

Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene.

Yanagisawa H, Yanagisawa M, Kapur RP, Richardson JA, Williams SC, Clouthier DE, de Wit D, Emoto N, Hammer RE.

Development. 1998 Mar;125(5):825-36.

11.

Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development.

Yanagisawa H, Hammer RE, Richardson JA, Emoto N, Williams SC, Takeda Si, Clouthier DE, Yanagisawa M.

J Clin Invest. 2000 May;105(10):1373-82.

12.

Endothelin-converting enzyme-1 increases in atherosclerotic mice: potential role of oxidized low density lipoproteins.

Martínez-Miguel P, Raoch V, Zaragoza C, Valdivielso JM, Rodríguez-Puyol M, Rodríguez-Puyol D, López-Ongil S.

J Lipid Res. 2009 Mar;50(3):364-75. doi: 10.1194/jlr.M800215-JLR200. Epub 2008 Nov 7.

13.

Mice lacking rhes show altered morphine analgesia, tolerance, and dependence.

Lee FA, Baiamonte BA, Spano D, Lahoste GJ, Soignier RD, Harrison LM.

Neurosci Lett. 2011 Feb 11;489(3):182-6. doi: 10.1016/j.neulet.2010.12.012. Epub 2010 Dec 14.

14.

Molecular pharmacology of endothelin converting enzymes.

Turner AJ, Murphy LJ.

Biochem Pharmacol. 1996 Jan 26;51(2):91-102. Review.

PMID:
8615890
15.

[Activation of the spinal extracellular signal-regulated kinase is involved in morphine dependence and naloxone-precipitated withdrawal response].

He JH, Cao JL, Xu YB, Song XS, Ding HL, Zeng YM.

Sheng Li Xue Bao. 2005 Oct 25;57(5):557-65. Chinese.

16.

Physiological relevance of hydrolysis of atrial natriuretic peptide by endothelin-converting enzyme-1.

Nakayama K, Emoto N, Suzuki Y, Vignon-Zellweger N, Yagi K, Hirata K.

Kobe J Med Sci. 2012 Jun 21;58(1):E12-8.

17.
18.

Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2.

Gagnidze K, Sachchidanand, Rozenfeld R, Mezei M, Zhou MM, Devi LA.

J Med Chem. 2008 Jun 26;51(12):3378-87. doi: 10.1021/jm7015478. Epub 2008 May 29.

19.

Heterodimerization of endothelin-converting enzyme-1 isoforms regulates the subcellular distribution of this metalloprotease.

Muller L, Barret A, Etienne E, Meidan R, Valdenaire O, Corvol P, Tougard C.

J Biol Chem. 2003 Jan 3;278(1):545-55. Epub 2002 Oct 21.

20.

Implication of endogenous beta-endorphin in the inhibition of the morphine-induced rewarding effect by the direct activation of spinal protein kinase C in mice.

Niikura K, Narita M, Okutsu D, Tsurukawa Y, Nanjo K, Kurahashi K, Kobayashi Y, Suzuki T.

Neurosci Lett. 2008 Mar 5;433(1):54-8. doi: 10.1016/j.neulet.2007.12.042. Epub 2008 Feb 8.

PMID:
18262361

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