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Items: 1 to 20 of 96

1.

Identification of key residues involved in the dimerization of the secretory Na(+)-K(+)-2Cl(-) cotransporter NKCC1.

Parvin MN, Turner RJ.

Biochemistry. 2011 Nov 15;50(45):9857-64. doi: 10.1021/bi201498y. Epub 2011 Oct 19.

2.

Regions in the cytosolic C-terminus of the secretory Na(+)-K(+)-2Cl(-) cotransporter NKCC1 are required for its homodimerization.

Parvin MN, Gerelsaikhan T, Turner RJ.

Biochemistry. 2007 Aug 21;46(33):9630-7. Epub 2007 Jul 27.

PMID:
17655331
3.

A conserved hydrophobic tetrad near the C terminus of the secretory Na+-K+-2Cl- cotransporter (NKCC1) is required for its correct intracellular processing.

Nezu A, Parvin MN, Turner RJ.

J Biol Chem. 2009 Mar 13;284(11):6869-76. doi: 10.1074/jbc.M804302200. Epub 2009 Jan 7.

4.

A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.

Gagnon KB, England R, Delpire E.

Cell Physiol Biochem. 2007;20(1-4):131-42.

5.

Molecular determinants of hyperosmotically activated NKCC1-mediated K+/K+ exchange.

Gagnon KB, Delpire E.

J Physiol. 2010 Sep 15;588(Pt 18):3385-96. doi: 10.1113/jphysiol.2010.191932. Epub 2010 Jun 7.

6.

Regulatory activation is accompanied by movement in the C terminus of the Na-K-Cl cotransporter (NKCC1).

Monette MY, Forbush B.

J Biol Chem. 2012 Jan 13;287(3):2210-20. doi: 10.1074/jbc.M111.309211. Epub 2011 Nov 25.

8.

Identification of a functionally important conformation-sensitive region of the secretory Na+-K+-2Cl- cotransporter (NKCC1).

Dehaye JP, Nagy A, Premkumar A, Turner RJ.

J Biol Chem. 2003 Apr 4;278(14):11811-7. Epub 2003 Jan 29.

9.

Cotransport of water by Na⁺-K⁺-2Cl⁻ cotransporters expressed in Xenopus oocytes: NKCC1 versus NKCC2.

Zeuthen T, Macaulay N.

J Physiol. 2012 Mar 1;590(5):1139-54. doi: 10.1113/jphysiol.2011.226316. Epub 2012 Jan 16.

10.

A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1.

Darman RB, Forbush B.

J Biol Chem. 2002 Oct 4;277(40):37542-50. Epub 2002 Jul 26.

11.

Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers.

Ponce-Coria J, Gagnon KB, Delpire E.

Am J Physiol Cell Physiol. 2012 Dec 1;303(11):C1198-205. doi: 10.1152/ajpcell.00284.2012. Epub 2012 Oct 3.

12.

The role of transmembrane domain 2 in cation transport by the Na-K-Cl cotransporter.

Isenring P, Jacoby SC, Forbush B 3rd.

Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):7179-84.

13.

Biogenesis and topology of the secretory Na+-K+-2Cl- cotransporter (NKCC1) studied in intact mammalian cells.

Gerelsaikhan T, Parvin MN, Turner RJ.

Biochemistry. 2006 Oct 3;45(39):12060-7.

PMID:
17002305
14.

Multiple evolutionarily conserved Di-leucine like motifs in the carboxyl terminus control the anterograde trafficking of NKCC2.

Zaarour N, Demaretz S, Defontaine N, Zhu Y, Laghmani K.

J Biol Chem. 2012 Dec 14;287(51):42642-53. doi: 10.1074/jbc.M112.399162. Epub 2012 Oct 26.

15.

PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1).

Dowd BF, Forbush B.

J Biol Chem. 2003 Jul 25;278(30):27347-53. Epub 2003 May 9.

16.

On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity.

Gagnon KB, Delpire E.

Am J Physiol Cell Physiol. 2010 Sep;299(3):C614-20. doi: 10.1152/ajpcell.00074.2010. Epub 2010 May 12. Erratum in: Am J Physiol Cell Physiol. 2010 Sep;299(3):C614.

17.

Activity of the renal Na+-K+-2Cl- cotransporter is reduced by mutagenesis of N-glycosylation sites: role for protein surface charge in Cl- transport.

Paredes A, Plata C, Rivera M, Moreno E, Vázquez N, Muñoz-Clares R, Hebert SC, Gamba G.

Am J Physiol Renal Physiol. 2006 May;290(5):F1094-102. Epub 2005 Nov 15.

18.

Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody.

Flemmer AW, Gimenez I, Dowd BF, Darman RB, Forbush B.

J Biol Chem. 2002 Oct 4;277(40):37551-8. Epub 2002 Jul 26.

19.

COMMD1 interacts with the COOH terminus of NKCC1 in Calu-3 airway epithelial cells to modulate NKCC1 ubiquitination.

Smith L, Litman P, Liedtke CM.

Am J Physiol Cell Physiol. 2013 Jul 15;305(2):C133-46. doi: 10.1152/ajpcell.00394.2012. Epub 2013 Mar 20.

20.

Contribution of the basolateral isoform of the Na-K-2Cl- cotransporter (NKCC1/BSC2) to renin secretion.

Castrop H, Lorenz JN, Hansen PB, Friis U, Mizel D, Oppermann M, Jensen BL, Briggs J, Skøtt O, Schnermann J.

Am J Physiol Renal Physiol. 2005 Dec;289(6):F1185-92. Epub 2005 Aug 16.

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