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Items: 1 to 20 of 214

1.

Is targeting eNOS a key mechanistic insight of cardiovascular defensive potentials of statins?

Balakumar P, Kathuria S, Taneja G, Kalra S, Mahadevan N.

J Mol Cell Cardiol. 2012 Jan;52(1):83-92. doi: 10.1016/j.yjmcc.2011.09.014. Epub 2011 Sep 24. Review.

PMID:
21968328
2.

Modulatory effects of HMG-CoA reductase inhibitors in diabetic microangiopathy.

Danesh FR, Kanwar YS.

FASEB J. 2004 May;18(7):805-15. Review.

PMID:
15117885
3.

Interplay between statins and PPARs in improving cardiovascular outcomes: a double-edged sword?

Balakumar P, Mahadevan N.

Br J Pharmacol. 2012 Jan;165(2):373-9. doi: 10.1111/j.1476-5381.2011.01597.x. Review.

4.

A pharmacogenetics-based approach to reduce cardiovascular mortality with the prophylactic use of statins.

Lacchini R, Silva PS, Tanus-Santos JE.

Basic Clin Pharmacol Toxicol. 2010 May;106(5):357-61. doi: 10.1111/j.1742-7843.2010.00551.x. Epub 2010 Mar 4. Review.

5.

Beyond lipid-lowering: effects of statins on endothelial nitric oxide.

Laufs U.

Eur J Clin Pharmacol. 2003 Mar;58(11):719-31. Epub 2003 Feb 18. Review.

PMID:
12634978
6.

Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors.

Harris MB, Blackstone MA, Sood SG, Li C, Goolsby JM, Venema VJ, Kemp BE, Venema RC.

Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H560-6. Epub 2004 Apr 15.

7.

Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/NF-kappaB pathway.

Nakata S, Tsutsui M, Shimokawa H, Yamashita T, Tanimoto A, Tasaki H, Ozumi K, Sabanai K, Morishita T, Suda O, Hirano H, Sasaguri Y, Nakashima Y, Yanagihara N.

Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):92-8. Epub 2006 Nov 2.

8.

Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells.

Jantzen F, Könemann S, Wolff B, Barth S, Staudt A, Kroemer HK, Dahm JB, Felix SB, Landsberger M.

J Physiol Pharmacol. 2007 Sep;58(3):503-14.

9.

Statins, nitric oxide and neovascularization.

Ma FX, Han ZC.

Cardiovasc Drug Rev. 2005 Winter;23(4):281-92. Review.

PMID:
16614729
10.

Rho GTPases, statins, and nitric oxide.

Rikitake Y, Liao JK.

Circ Res. 2005 Dec 9;97(12):1232-5. Review.

11.

Statins: a new insight into their mechanisms of action and consequent pleiotropic effects.

Jasińska M, Owczarek J, Orszulak-Michalak D.

Pharmacol Rep. 2007 Sep-Oct;59(5):483-99. Review.

12.

Statin treatment and 3' polyadenylation of eNOS mRNA.

Kosmidou I, Moore JP, Weber M, Searles CD.

Arterioscler Thromb Vasc Biol. 2007 Dec;27(12):2642-9. Epub 2007 Oct 4.

13.

Influence of statin use on endothelial function: from bench to clinics.

Martínez-González J, Badimon L.

Curr Pharm Des. 2007;13(17):1771-86. Review.

PMID:
17584107
14.

Inhibition of LOX-1 by statins may relate to upregulation of eNOS.

Mehta JL, Li DY, Chen HJ, Joseph J, Romeo F.

Biochem Biophys Res Commun. 2001 Dec 14;289(4):857-61.

PMID:
11735125
15.

Cross-talk between exogenous statins and endogenous high-density lipoprotein in anti-inflammatory and anti-atherogenic actions.

Kimura T, Sato K, Tomura H, Okajima F.

Endocr Metab Immune Disord Drug Targets. 2010 Mar;10(1):8-15. Review.

PMID:
20105136
16.

[Novel actions of HMG-CoA reductase inhibitors(statins)--vascular and cerebral protection through inhibition of small GTPase Rho].

Sawada N, Itoh H, Nakao K.

Nihon Rinsho. 2001 Dec;59(12):2470-5. Review. Japanese.

PMID:
11766357
17.

Recent developments in the effects of nitric oxide-donating statins on cardiovascular disease through regulation of tetrahydrobiopterin and nitric oxide.

Ma S, Ma CC.

Vascul Pharmacol. 2014 Nov;63(2):63-70. doi: 10.1016/j.vph.2014.08.001. Epub 2014 Aug 17. Review.

PMID:
25139660
18.

Antioxidative effects of statins.

Adam O, Laufs U.

Arch Toxicol. 2008 Dec;82(12):885-92. doi: 10.1007/s00204-008-0344-4. Epub 2008 Aug 1. Review.

PMID:
18670762
19.

Pleiotropic effects of statins and related pharmacological experimental approaches.

Alegret M, Silvestre JS.

Methods Find Exp Clin Pharmacol. 2006 Nov;28(9):627-56. Review.

PMID:
17200729
20.

The effects of statins on endothelium, inflammation and cardioprotection.

Elrod JW, Lefer DJ.

Drug News Perspect. 2005 May;18(4):229-36. Review.

PMID:
16034478

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