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21967546,21670448,17579862,20439648,18081718,22289988,22291086,26234722,23701943,22339826,15746041,18955790,19296110,29786546,22736495,23540998,19176014,16185475,22535592,26223865,17145823,16642044,18450602,12115363,19176010,30926392,15329908,24512939,16330434,11585760,18261272,18343790,21537333,12551822,15289019,24054719,21744003,25172541,22208491,20172040,19840437,16418499,19536888,22099191,12973844,28616699,27626217,30122013,20684989,20148885,28100593,21173125,12801839,23018865,26676635,15059064,12200684,19995225,23480665,35485701,20513120,17233551,29079128,15889156,22766221,22362118,23473998,22659680,22911473,23276395,22939316,22674490,25964253,23962568,26551637,22749068,30503388,32495317,23385863,22104247,25609058,29498106,21523728,25281355,23233047,29165010,32447933,31694106,31572552,22487825,19176031,33811005,23783394,31207705,24767158,23511494,34376373,26242829,26299958,28164537,29624746,24301914,33340276,34487021,26438511,26537612,26547258,31237017,28627830,27062340,25042343,25260824,25371149,27636998,21523727,33109387,29665898,31190985,22077061,27373815,21133602,29188605,23815907,26033747,36610002,27050425,27476855,26488113,24138945,21518476,24498869,30369187,22821298,22338050,32970934,34978724,19151774,23431389,28407515,31965269,29961066,19603346,32728112,29950203,35549661,24824767,23341344,25643589,36765475,25994761,26759106,24078567,28088961,23998566,26375248,24464319,29904089,22081665,22213860,32311890,23135354,25948179,19878996,27315441,27033755,25794001,16453003,20670134,15061200,34671057,23708641,20302766,25314777,22490330,14977832,25241285,19840439,28052408,25650308,27893163,28598126,23647058,14671635,33491606,26230955,35395962,26692109,23760853,26586702,27797237,32944990,27247325,28767575,25183446,26010177,26134006,25860933,24598649,20542566,23713453,30180463,25481050,28370339,19282830,30970181,26796102,23257420,27478011,24962064,33765335,32552926,23115274,31055804,22504140,31698462,25592059,36163632,26290145,28830460,30555035,25596267,29663558,30455361,26765290,25554589,27016502,26191952,26781613,32103499,23582927,28058491,21176335,22338176,33913388,21423122,27055875,29166740,27140705,24685333,31171000,25155901,30009341,28024465,31694105,29950146,27706846,33784904,22417203,29806051,25434303,28070990,26524018,28710806,32476595,21576631,31807186,23632886,26338961,23154527,26517501,25592687,30846862,32597790,17361227,23439754,33706968,31331874,31149783,30969080,26002514,31145495,22169324,22072438,27636548,33839881,33250015,28428668,32730663,25022553,28940816,12351377,7934163,22291079,17708787,22647869,29643943,24223248,29903761,24936645,2564452,25145343,32019476,15618961,24138595,21067377,28102729,28395440,27841873,33677867,35680801,32699322,31665853,30190467,28088962,29309772,34105453,19158829,20548095,33415016,36912186,29321554,28810326,27288520,23384906,36738279,27733013,24056881,26314419,23690417,31373163,34100902,29702001,24857207,29573577,29534404,22781717,26755712,32527994,21127174,25652455,20723330,24390456,29601269,28933735,24565682,30357752,25204082,24283755,22987373,23190472,23929217,21239839,24135052,20625116,31291961,18156731,32229198,26681050,28960408,31607296,26071459,24782118,35666642,32124426,31348835,25550847,23597455,1318461,23237559,26482067,36318614,25152118,34627418,28618016,31099482,24957411,25449073,32796597,26351014,22924777,23313659,27881874,26563907,33737834,32173273,33812399,26771088,35981366,11455972,29172276,30612396,23201546,26038140,27771989,25200361,21826063,30122998,28286768,30942411,22488577,35967966,29390924,29408852,29563537,22915647,26707798,20726318,21415852,29472724,29491461,25721756,26856970,33678591,33299888,35473465,22052552,29166738,24767404,35387132,21904384,32176633,22684224,26002512,21836609,27149454,26711182,34453673,30968396,27983727,23992300,27528035,19171881,21917756,28556489,26458431,21729688,23444869,24606662,26820131,28823257,22855599,33067935,33947035,28851457,12702504,21537334,31518054,27470916,29721667,27511899,28643785,33113604,33333221,33968731,20592250,27736291,30017658,23619823,25303497,22251315,24156414,34410352,25687040,25858894,27400753,29843647,18056840,22642896,24280869,34700049,31638252,28825596,22725130,28753595,27374030,32628327,27689396,31263671,29326119,36580013,32902355,16507781,23133988,33283233,25934556,21399634,33317436,29872168,23667841,29262888,35681796,28484171,35123602,32461631,27305704,34466057,29877252,25748685,28777858,23233559,37144777,29024628,36279042,27991732,25088035,31839044,28548938,29619119,26992835,31281149,29692343,28345823,26155911,31808755,23240632,25248875,36304735,33998238,22887079,29556023,25443887,28883284,32127298,34627254,23952244,31719678,31856443,36175738,36370049,27566555,21880636,34627423,30309854,33915454,34787059,26666339,32754299,22407852,35986270,30122995,26838606,30069492,23535558,34351647,27300438,35288759,28751771,32027256,28378367,35227274,30610028,28980058,22543745,23380602,30655366,31440963,21873548,28418922,29227476,27566651,34459887,23969309,32943750,36073548,27724883,26072070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665 results

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Prognostic impact of DNMT3A mutations in patients with intermediate cytogenetic risk profile acute myeloid leukemia.

Marková J, Michková P, Burčková K, Březinová J, Michalová K, Dohnalová A, Maaloufová JS, Soukup P, Vítek A, Cetkovský P, Schwarz J. Marková J, et al. Eur J Haematol. 2012 Feb;88(2):128-35. doi: 10.1111/j.1600-0609.2011.01716.x. Epub 2011 Nov 17. Eur J Haematol. 2012. PMID: 21967546

Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.

Thol F, Damm F, Lüdeking A, Winschel C, Wagner K, Morgan M, Yun H, Göhring G, Schlegelberger B, Hoelzer D, Lübbert M, Kanz L, Fiedler W, Kirchner H, Heil G, Krauter J, Ganser A, Heuser M. Thol F, et al. J Clin Oncol. 2011 Jul 20;29(21):2889-96. doi: 10.1200/JCO.2011.35.4894. Epub 2011 Jun 13. J Clin Oncol. 2011. PMID: 21670448 Clinical Trial.

Importance of early detection and follow-up of FLT3 mutations in patients with acute myeloid leukemia.

Colovic N, Tosic N, Aveic S, Djuric M, Milic N, Bumbasirevic V, Colovic M, Pavlovic S. Colovic N, et al. Ann Hematol. 2007 Oct;86(10):741-7. doi: 10.1007/s00277-007-0325-3. Epub 2007 Jun 20. Ann Hematol. 2007. PMID: 17579862

Prognostic significance of CEBPA mutations in a large cohort of younger adult patients with acute myeloid leukemia: impact of double CEBPA mutations and the interaction with FLT3 and NPM1 mutations.

Green CL, Koo KK, Hills RK, Burnett AK, Linch DC, Gale RE. Green CL, et al. J Clin Oncol. 2010 Jun 1;28(16):2739-47. doi: 10.1200/JCO.2009.26.2501. Epub 2010 May 3. J Clin Oncol. 2010. PMID: 20439648

Clinical impact of nucleophosmin mutations and Flt3 internal tandem duplications in patients older than 60 yr with acute myeloid leukaemia.

Scholl S, Theuer C, Scheble V, Kunert C, Heller A, Mügge LO, Fricke HJ, Höffken K, Wedding U. Scholl S, et al. Eur J Haematol. 2008 Mar;80(3):208-15. doi: 10.1111/j.1600-0609.2007.01019.x. Eur J Haematol. 2008. PMID: 18081718

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.

Renneville A, Boissel N, Nibourel O, Berthon C, Helevaut N, Gardin C, Cayuela JM, Hayette S, Reman O, Contentin N, Bordessoule D, Pautas C, Botton Sd, Revel Td, Terre C, Fenaux P, Thomas X, Castaigne S, Dombret H, Preudhomme C. Renneville A, et al. Leukemia. 2012 Jun;26(6):1247-54. doi: 10.1038/leu.2011.382. Epub 2012 Jan 13. Leukemia. 2012. PMID: 22289988

Impact of FLT3 internal tandem duplication on the outcome of related and unrelated hematopoietic transplantation for adult acute myeloid leukemia in first remission: a retrospective analysis.

Brunet S, Labopin M, Esteve J, Cornelissen J, Socié G, Iori AP, Verdonck LF, Volin L, Gratwohl A, Sierra J, Mohty M, Rocha V. Brunet S, et al. J Clin Oncol. 2012 Mar 1;30(7):735-41. doi: 10.1200/JCO.2011.36.9868. Epub 2012 Jan 30. J Clin Oncol. 2012. PMID: 22291086

DNMT3A R882 Mutation with FLT3-ITD Positivity Is an Extremely Poor Prognostic Factor in Patients with Normal-Karyotype Acute Myeloid Leukemia after Allogeneic Hematopoietic Cell Transplantation.

Ahn JS, Kim HJ, Kim YK, Lee SS, Jung SH, Yang DH, Lee JJ, Kim NY, Choi SH, Jung CW, Jang JH, Kim HJ, Moon JH, Sohn SK, Won JH, Kim SH, Kim DD. Ahn JS, et al. Biol Blood Marrow Transplant. 2016 Jan;22(1):61-70. doi: 10.1016/j.bbmt.2015.07.030. Epub 2015 Jul 31. Biol Blood Marrow Transplant. 2016. PMID: 26234722 Free article. Clinical Trial.

CD34 expression predicts an adverse outcome in patients with NPM1-positive acute myeloid leukemia.

Dang H, Chen Y, Kamel-Reid S, Brandwein J, Chang H. Dang H, et al. Hum Pathol. 2013 Oct;44(10):2038-46. doi: 10.1016/j.humpath.2013.03.007. Epub 2013 May 21. Hum Pathol. 2013. PMID: 23701943

[Analysis of tyrosine kinases gene mutations in core binding factor related acute myeloid leukemia and its clinical significance].

Qiao M, Li WY, Sun AN, Chen SN, Liang JY, Ding ZX, Feng YF, Wu DP. Qiao M, et al. Zhonghua Xue Ye Xue Za Zhi. 2011 Oct;32(10):679-83. Zhonghua Xue Ye Xue Za Zhi. 2011. PMID: 22339826 Chinese.

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