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Items: 1 to 20 of 108

1.

Roles for cardiac MyBP-C in maintaining myofilament lattice rigidity and prolonging myosin cross-bridge lifetime.

Palmer BM, Sadayappan S, Wang Y, Weith AE, Previs MJ, Bekyarova T, Irving TC, Robbins J, Maughan DW.

Biophys J. 2011 Oct 5;101(7):1661-9. doi: 10.1016/j.bpj.2011.08.047.

2.

Protein kinase A-mediated phosphorylation of cMyBP-C increases proximity of myosin heads to actin in resting myocardium.

Colson BA, Bekyarova T, Locher MR, Fitzsimons DP, Irving TC, Moss RL.

Circ Res. 2008 Aug 1;103(3):244-51. doi: 10.1161/CIRCRESAHA.108.178996. Epub 2008 Jul 3.

3.

Cardiac myosin binding protein-C phosphorylation in a {beta}-myosin heavy chain background.

Sadayappan S, Gulick J, Klevitsky R, Lorenz JN, Sargent M, Molkentin JD, Robbins J.

Circulation. 2009 Mar 10;119(9):1253-62. doi: 10.1161/CIRCULATIONAHA.108.798983. Epub 2009 Feb 23.

4.

Cardiac myosin binding protein C phosphorylation is cardioprotective.

Sadayappan S, Osinska H, Klevitsky R, Lorenz JN, Sargent M, Molkentin JD, Seidman CE, Seidman JG, Robbins J.

Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16918-23. Epub 2006 Oct 30.

5.

Ablation of myosin-binding protein-C accelerates force development in mouse myocardium.

Stelzer JE, Fitzsimons DP, Moss RL.

Biophys J. 2006 Jun 1;90(11):4119-27. Epub 2006 Mar 2.

6.

Radial displacement of myosin cross-bridges in mouse myocardium due to ablation of myosin binding protein-C.

Colson BA, Bekyarova T, Fitzsimons DP, Irving TC, Moss RL.

J Mol Biol. 2007 Mar 16;367(1):36-41. Epub 2006 Dec 28.

7.

Protein kinase A-induced myofilament desensitization to Ca(2+) as a result of phosphorylation of cardiac myosin-binding protein C.

Chen PP, Patel JR, Rybakova IN, Walker JW, Moss RL.

J Gen Physiol. 2010 Dec;136(6):615-27. doi: 10.1085/jgp.201010448.

8.

Control of in vivo left ventricular [correction] contraction/relaxation kinetics by myosin binding protein C: protein kinase A phosphorylation dependent and independent regulation.

Nagayama T, Takimoto E, Sadayappan S, Mudd JO, Seidman JG, Robbins J, Kass DA.

Circulation. 2007 Nov 20;116(21):2399-408. Epub 2007 Nov 5. Erratum in: Circulation. 2008 Jan 1/8;117(1):e11.

9.

Molecular effects of the myosin activator omecamtiv mecarbil on contractile properties of skinned myocardium lacking cardiac myosin binding protein-C.

Mamidi R, Gresham KS, Li A, dos Remedios CG, Stelzer JE.

J Mol Cell Cardiol. 2015 Aug;85:262-72. doi: 10.1016/j.yjmcc.2015.06.011. Epub 2015 Jun 20.

10.

Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.

Palmer BM, McConnell BK, Li GH, Seidman CE, Seidman JG, Irving TC, Alpert NR, Maughan DW.

Mol Cell Biochem. 2004 Aug;263(1-2):73-80.

PMID:
15524168
11.

Cardiac myosin-binding protein-C phosphorylation and cardiac function.

Sadayappan S, Gulick J, Osinska H, Martin LA, Hahn HS, Dorn GW 2nd, Klevitsky R, Seidman CE, Seidman JG, Robbins J.

Circ Res. 2005 Nov 25;97(11):1156-63. Epub 2005 Oct 13.

12.

Kinetics of cardiac myosin isoforms in mouse myocardium are affected differently by presence of myosin binding protein-C.

Tanner BC, Wang Y, Robbins J, Palmer BM.

J Muscle Res Cell Motil. 2014 Dec;35(5-6):267-78. doi: 10.1007/s10974-014-9390-0. Epub 2014 Oct 7.

13.

Cardiac Myosin-binding Protein C and Troponin-I Phosphorylation Independently Modulate Myofilament Length-dependent Activation.

Kumar M, Govindan S, Zhang M, Khairallah RJ, Martin JL, Sadayappan S, de Tombe PP.

J Biol Chem. 2015 Dec 4;290(49):29241-9. doi: 10.1074/jbc.M115.686790. Epub 2015 Oct 9.

14.

Distinct sarcomeric substrates are responsible for protein kinase D-mediated regulation of cardiac myofilament Ca2+ sensitivity and cross-bridge cycling.

Bardswell SC, Cuello F, Rowland AJ, Sadayappan S, Robbins J, Gautel M, Walker JW, Kentish JC, Avkiran M.

J Biol Chem. 2010 Feb 19;285(8):5674-82. doi: 10.1074/jbc.M109.066456. Epub 2009 Dec 17.

15.
16.

Multiple forms of cardiac myosin-binding protein C exist and can regulate thick filament stability.

Kulikovskaya I, McClellan GB, Levine R, Winegrad S.

J Gen Physiol. 2007 May;129(5):419-28. Erratum in: J Gen Physiol. 2009 Feb;133(2):225.

17.

Reduced cross-bridge dependent stiffness of skinned myocardium from mice lacking cardiac myosin binding protein-C.

Palmer BM, McConnell BK, Li GH, Seidman CE, Seidman JG, Irving TC, Alpert NR, Maughan DW.

Mol Cell Biochem. 2004 Aug;263(1):73-80. doi: 10.1023/B:MCBI.0000041849.60591.45.

PMID:
27520666
18.

Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium.

Colson BA, Patel JR, Chen PP, Bekyarova T, Abdalla MI, Tong CW, Fitzsimons DP, Irving TC, Moss RL.

J Mol Cell Cardiol. 2012 Nov;53(5):609-16. doi: 10.1016/j.yjmcc.2012.07.012. Epub 2012 Jul 28.

19.

Ablation of cardiac myosin-binding protein-C accelerates stretch activation in murine skinned myocardium.

Stelzer JE, Dunning SB, Moss RL.

Circ Res. 2006 May 12;98(9):1212-8. Epub 2006 Mar 30.

20.

Molecular mechanics of cardiac myosin-binding protein C in native thick filaments.

Previs MJ, Beck Previs S, Gulick J, Robbins J, Warshaw DM.

Science. 2012 Sep 7;337(6099):1215-8. doi: 10.1126/science.1223602. Epub 2012 Aug 23.

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