Similar articles for PMID: 21949132

Year	Number of Results
2005	2
2006	6
2007	11
2008	8
2009	5
2010	3
2011	16
2012	22
2013	27
2014	18
2015	15
2016	4
2017	6
2018	6
2019	6
2020	4
2021	6
2022	11
2023	3
2024	0

1

TNF-α and IL-1β promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc.

Wang J, Markova D, Anderson DG, Zheng Z, Shapiro IM, Risbud MV. Wang J, et al. J Biol Chem. 2011 Nov 18;286(46):39738-49. doi: 10.1074/jbc.M111.264549. Epub 2011 Sep 23. J Biol Chem. 2011. PMID: 21949132 Free PMC article.

2

Bone morphogenetic protein-7 antagonizes tumor necrosis factor-α-induced activation of nuclear factor κB and up-regulation of the ADAMTS, leading to decreased degradation of disc matrix macromolecules aggrecan and collagen II.

Wang Z, Hutton WC, Yoon ST. Wang Z, et al. Spine J. 2014 Mar 1;14(3):505-12. doi: 10.1016/j.spinee.2013.08.016. Epub 2013 Oct 29. Spine J. 2014. PMID: 24176808

3

Inflammatory cytokines associated with degenerative disc disease control aggrecanase-1 (ADAMTS-4) expression in nucleus pulposus cells through MAPK and NF-κB.

Tian Y, Yuan W, Fujita N, Wang J, Wang H, Shapiro IM, Risbud MV. Tian Y, et al. Am J Pathol. 2013 Jun;182(6):2310-21. doi: 10.1016/j.ajpath.2013.02.037. Epub 2013 Apr 17. Am J Pathol. 2013. PMID: 23602832 Free PMC article.

4

IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc.

Sun Z, Yin Z, Liu C, Liang H, Jiang M, Tian J. Sun Z, et al. J Orthop Surg Res. 2015 Oct 6;10:159. doi: 10.1186/s13018-015-0296-3. J Orthop Surg Res. 2015. PMID: 26438479 Free PMC article.

5

Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.

Fujita N, Gogate SS, Chiba K, Toyama Y, Shapiro IM, Risbud MV. Fujita N, et al. J Biol Chem. 2012 Nov 16;287(47):39942-53. doi: 10.1074/jbc.M112.375964. Epub 2012 Sep 4. J Biol Chem. 2012. PMID: 22948157 Free PMC article.

6

Aggrecanase and aggrecan degradation in osteoarthritis: a review.

Huang K, Wu LD. Huang K, et al. J Int Med Res. 2008 Nov-Dec;36(6):1149-60. doi: 10.1177/147323000803600601. J Int Med Res. 2008. PMID: 19094423 Free article. Review.

7

Upregulation of tumor necrosis factor α and ADAMTS-5, but not ADAMTS-4, in human intervertebral cartilage endplate with modic changes.

Chen S, Huang Y, Zhou ZJ, Hu ZJ, Wang JY, Xu WB, Fang XQ, Fan SW. Chen S, et al. Spine (Phila Pa 1976). 2014 Jun 15;39(14):E817-25. doi: 10.1097/BRS.0000000000000362. Spine (Phila Pa 1976). 2014. PMID: 24732836

8

Syndecan-4 in intervertebral disc and cartilage: Saint or synner?

Binch ALA, Shapiro IM, Risbud MV. Binch ALA, et al. Matrix Biol. 2016 May-Jul;52-54:355-362. doi: 10.1016/j.matbio.2016.01.005. Epub 2016 Jan 18. Matrix Biol. 2016. PMID: 26796346 Free PMC article. Review.

9

Tumor necrosis factor-α- and interleukin-1β-dependent matrix metalloproteinase-3 expression in nucleus pulposus cells requires cooperative signaling via syndecan 4 and mitogen-activated protein kinase-NF-κB axis: implications in inflammatory disc disease.

Wang X, Wang H, Yang H, Li J, Cai Q, Shapiro IM, Risbud MV. Wang X, et al. Am J Pathol. 2014 Sep;184(9):2560-72. doi: 10.1016/j.ajpath.2014.06.006. Epub 2014 Jul 22. Am J Pathol. 2014. PMID: 25063530 Free PMC article.

10

Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.

Li J, Yuan W, Jiang S, Ye W, Yang H, Shapiro IM, Risbud MV. Li J, et al. J Biol Chem. 2015 Mar 13;290(11):7195-207. doi: 10.1074/jbc.M114.611483. Epub 2015 Jan 29. J Biol Chem. 2015. PMID: 25635047 Free PMC article.

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