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Items: 1 to 20 of 103

1.

Remote control of regioselectivity in acyl-acyl carrier protein-desaturases.

Guy JE, Whittle E, Moche M, Lengqvist J, Lindqvist Y, Shanklin J.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16594-9. doi: 10.1073/pnas.1110221108. Epub 2011 Sep 19.

2.

A multifunctional acyl-acyl carrier protein desaturase from Hedera helix L. (English ivy) can synthesize 16- and 18-carbon monoene and diene products.

Whittle E, Cahoon EB, Subrahmanyam S, Shanklin J.

J Biol Chem. 2005 Aug 5;280(31):28169-76. Epub 2005 Jun 6.

3.

Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position.

Cahoon EB, Lindqvist Y, Schneider G, Shanklin J.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):4872-7.

4.

Revealing the catalytic potential of an acyl-ACP desaturase: tandem selective oxidation of saturated fatty acids.

Whittle EJ, Tremblay AE, Buist PH, Shanklin J.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14738-43. doi: 10.1073/pnas.0805645105. Epub 2008 Sep 16.

5.

The crystal structure of the ivy Delta4-16:0-ACP desaturase reveals structural details of the oxidized active site and potential determinants of regioselectivity.

Guy JE, Whittle E, Kumaran D, Lindqvist Y, Shanklin J.

J Biol Chem. 2007 Jul 6;282(27):19863-71. Epub 2007 Apr 26.

6.

Mechanistic and structural insights into the regioselectivity of an acyl-CoA fatty acid desaturase via directed molecular evolution.

Vanhercke T, Shrestha P, Green AG, Singh SP.

J Biol Chem. 2011 Apr 15;286(15):12860-9. doi: 10.1074/jbc.M110.191098. Epub 2011 Feb 7.

7.
9.

Characterization of a structurally and functionally diverged acyl-acyl carrier protein desaturase from milkweed seed.

Cahoon EB, Coughlan SJ, Shanklin J.

Plant Mol Biol. 1997 Apr;33(6):1105-10.

PMID:
9154992
10.

Desaturation of trans-octadecenoyl-acyl carrier protein by stearoyl-acyl carrier protein delta9 desaturase.

Broadwater JA, Laundre BJ, Fox BG.

J Inorg Biochem. 2000 Jan 15;78(1):7-14.

PMID:
10714700
11.

Structure determinants for the substrate specificity of acyl-CoA Δ9 desaturases from a marine copepod.

Meesapyodsuk D, Qiu X.

ACS Chem Biol. 2014 Apr 18;9(4):922-34. doi: 10.1021/cb400675d. Epub 2014 Jan 29.

PMID:
24475735
13.
14.
17.

A single mutation in the castor Delta9-18:0-desaturase changes reaction partitioning from desaturation to oxidase chemistry.

Guy JE, Abreu IA, Moche M, Lindqvist Y, Whittle E, Shanklin J.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17220-4. Epub 2006 Nov 6.

18.

Biosynthesis of docosahexaenoic acid in Euglena gracilis: biochemical and molecular evidence for the involvement of a Delta4-fatty acyl group desaturase.

Meyer A, Cirpus P, Ott C, Schlecker R, Zähringer U, Heinz E.

Biochemistry. 2003 Aug 19;42(32):9779-88.

PMID:
12911321
19.

Palmitoleate formation by soybean stearoyl-acyl carrier protein desaturase.

Gibson KJ.

Biochim Biophys Acta. 1993 Sep 8;1169(3):231-5.

PMID:
7548115
20.

What limits production of unusual monoenoic fatty acids in transgenic plants?

Suh MC, Schultz DJ, Ohlrogge JB.

Planta. 2002 Aug;215(4):584-95. Epub 2002 Mar 27.

PMID:
12172841

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