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Items: 1 to 20 of 147

1.

667C>T and 1298A>C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia.

Lasecka L, Dixon PH, Molokhia M, Sharma N, Schleh A, Wang CM, Steel JH, Seckl MJ, Savage PM, Fisher RA.

Gynecol Oncol. 2011 Dec;123(3):605-9. doi: 10.1016/j.ygyno.2011.08.012. Epub 2011 Sep 13.

PMID:
21920590
2.
3.

High dose methotrexate treatment in childhood ALL: pilot study on the impact of the MTHFR 677C>T and 1298A>C polymorphisms on MTX-related toxicity.

Haase R, Elsner K, Merkel N, Stiefel M, Mauz-Körholz C, Kramm CM, Körholz D.

Klin Padiatr. 2012 Apr;224(3):156-9. doi: 10.1055/s-0032-1304623. Epub 2012 Apr 18.

PMID:
22513795
4.

Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.

Etienne MC, Formento JL, Chazal M, Francoual M, Magné N, Formento P, Bourgeon A, Seitz JF, Delpero JR, Letoublon C, Pezet D, Milano G.

Pharmacogenetics. 2004 Dec;14(12):785-92.

PMID:
15608557
5.
6.

Methylenetetrahydrofolate reductase gene polymorphisms c.677C/T and c.1298A/C are not associated with open angle glaucoma.

Mabuchi F, Tang S, Kashiwagi K, Yamagata Z, Iijima H, Tsukahara S.

Mol Vis. 2006 Jul 7;12:735-9.

7.

Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms and toxicity to capecitabine in advanced colorectal cancer patients.

Sharma R, Hoskins JM, Rivory LP, Zucknick M, London R, Liddle C, Clarke SJ.

Clin Cancer Res. 2008 Feb 1;14(3):817-25. doi: 10.1158/1078-0432.CCR-07-0425.

9.

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

Wessels JA, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YP, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BA, Huizinga TW, Guchelaar HJ.

Arthritis Rheum. 2006 Apr;54(4):1087-95.

10.

677C>T and 1298A>C polymorphisms of methylenetetrahydropholate reductase gene and biochemical parameters in Turkish population with spina bifida occulta.

Eser B, Cosar M, Eser O, Erdogan MO, Aslan A, Yildiz H, Boyaci G, Buyukbas S, Solak M.

Turk Neurosurg. 2010 Jan;20(1):9-15.

11.
12.

5,10-Methylenetetrahydrofolate reductase 677C-->T and 1298A-->C mutations are genetic determinants of elevated homocysteine.

Castro R, Rivera I, Ravasco P, Jakobs C, Blom HJ, Camilo ME, de Almeida IT.

QJM. 2003 Apr;96(4):297-303.

PMID:
12651974
13.

Functional inference of the methylenetetrahydrofolate reductase 677C > T and 1298A > C polymorphisms from a large-scale epidemiological study.

Ulvik A, Ueland PM, Fredriksen A, Meyer K, Vollset SE, Hoff G, Schneede J.

Hum Genet. 2007 Mar;121(1):57-64. Epub 2006 Nov 18.

PMID:
17115185
14.

Investigation of the association between 677C>T and 1298A>C 5,10-methylenetetra- hydrofolate reductase gene polymorphisms and normal-tension glaucoma.

Woo SJ, Kim JY, Kim DM, Park SS, Ko HS, Yoo T.

Eye (Lond). 2009 Jan;23(1):17-24. Epub 2007 Jul 6.

PMID:
17618244
15.

MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer.

Afzal S, Jensen SA, Vainer B, Vogel U, Matsen JP, Sørensen JB, Andersen PK, Poulsen HE.

Ann Oncol. 2009 Oct;20(10):1660-6. doi: 10.1093/annonc/mdp046. Epub 2009 May 22.

PMID:
19465420
16.

The roles of methylenetetrahydrofolate reductase 677C>T and 1298A>C polymorphisms in moyamoya disease patients.

Park YS, Jeon YJ, Kim HS, Han IB, Choi JU, Kim DS, Kim NK.

Childs Nerv Syst. 2014 Oct;30(10):1687-95. doi: 10.1007/s00381-014-2495-3. Epub 2014 Aug 7.

PMID:
25098357
17.

[Association between the methylenetetrahydrofolate reductase gene polymorphisms and haplotype with toxicity response of high dose methotrexate chemotherapy].

Liao QC, Li XL, Liu ST, Zhang Y, Li TY, Qiu JC.

Zhonghua Liu Xing Bing Xue Za Zhi. 2012 Jul;33(7):735-9. Chinese.

PMID:
22968027
18.

Treatment of nonmetastatic and metastatic low-risk gestational trophoblastic neoplasia: factors associated with resistance to single-agent methotrexate chemotherapy.

Chapman-Davis E, Hoekstra AV, Rademaker AW, Schink JC, Lurain JR.

Gynecol Oncol. 2012 Jun;125(3):572-5. doi: 10.1016/j.ygyno.2012.03.039. Epub 2012 Mar 23.

PMID:
22449733
19.

Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population.

Schnakenberg E, Mehles A, Cario G, Rehe K, Seidemann K, Schlegelberger B, Elsner HA, Welte KH, Schrappe M, Stanulla M.

BMC Med Genet. 2005 May 27;6:23.

20.

[Polymorphism of methylenetetrahydrofolate reductase and sensitivity of stomach cancer to fluoropyrimidine-based chemotherapy].

Gao CM, Lu JW, Toshiro T, Wu JZ, Cao HX, Chen HQ, Feng JF, Kazuo T.

Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Dec;25(12):1054-8. Chinese.

PMID:
15769364

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