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Items: 1 to 20 of 161


Upregulation of CCR3 by age-related stresses promotes choroidal endothelial cell migration via VEGF-dependent and -independent signaling.

Wang H, Wittchen ES, Jiang Y, Ambati B, Grossniklaus HE, Hartnett ME.

Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8271-7. doi: 10.1167/iovs.11-8230.


Thy-1 Regulates VEGF-Mediated Choroidal Endothelial Cell Activation and Migration: Implications in Neovascular Age-Related Macular Degeneration.

Wang H, Han X, Kunz E, Hartnett ME.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5525-5534. doi: 10.1167/iovs.16-19691.


The role of RPE cell-associated VEGF₁₈₉ in choroidal endothelial cell transmigration across the RPE.

Wang H, Geisen P, Wittchen ES, King B, Burridge K, D'Amore PA, Hartnett ME.

Invest Ophthalmol Vis Sci. 2011 Feb 1;52(1):570-8. doi: 10.1167/iovs.10-5595. Print 2011 Jan.


Retinal Inhibition of CCR3 Induces Retinal Cell Death in a Murine Model of Choroidal Neovascularization.

Wang H, Han X, Gambhir D, Becker S, Kunz E, Liu AJ, Hartnett ME.

PLoS One. 2016 Jun 16;11(6):e0157748. doi: 10.1371/journal.pone.0157748. eCollection 2016.


Suppression of laser-induced choroidal neovascularization by a CCR3 antagonist.

Mizutani T, Ashikari M, Tokoro M, Nozaki M, Ogura Y.

Invest Ophthalmol Vis Sci. 2013 Feb 28;54(2):1564-72. doi: 10.1167/iovs.11-9095.


Heterotypic RPE-choroidal endothelial cell contact increases choroidal endothelial cell transmigration via PI 3-kinase and Rac1.

Peterson LJ, Wittchen ES, Geisen P, Burridge K, Hartnett ME.

Exp Eye Res. 2007 Apr;84(4):737-44. Epub 2006 Dec 23.


CCR3 is a target for age-related macular degeneration diagnosis and therapy.

Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J.

Nature. 2009 Jul 9;460(7252):225-30. doi: 10.1038/nature08151. Epub 2009 Jun 14.


Blood expression levels of chemokine receptor CCR3 and chemokine CCL11 in age-related macular degeneration: a case-control study.

Falk MK, Singh A, Faber C, Nissen MH, Hviid T, Sørensen TL.

BMC Ophthalmol. 2014 Feb 27;14:22. doi: 10.1186/1471-2415-14-22.


Rap1 GTPase Inhibits Tumor Necrosis Factor-α-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-κB-Dependent Activation of Rac1.

Wang H, Fotheringham L, Wittchen ES, Hartnett ME.

Am J Pathol. 2015 Dec;185(12):3316-25. doi: 10.1016/j.ajpath.2015.08.017. Epub 2015 Oct 23.


Regulation of signaling events involved in the pathophysiology of neovascular AMD.

Wang H, Hartnett ME.

Mol Vis. 2016 Feb 27;22:189-202. eCollection 2016. Review.


Novel role of ARF6 in vascular endothelial growth factor-induced signaling and angiogenesis.

Ikeda S, Ushio-Fukai M, Zuo L, Tojo T, Dikalov S, Patrushev NA, Alexander RW.

Circ Res. 2005 Mar 4;96(4):467-75. Epub 2005 Feb 3.


Vascular endothelial growth factor regulates primate choroid-retinal endothelial cell proliferation and tube formation through PI3K/Akt and MEK/ERK dependent signaling.

Jin J, Yuan F, Shen MQ, Feng YF, He QL.

Mol Cell Biochem. 2013 Sep;381(1-2):267-72. doi: 10.1007/s11010-013-1710-y. Epub 2013 Jun 8.


Breaking barriers: insight into the pathogenesis of neovascular age-related macular degeneration.

Wang H, Wittchen ES, Hartnett ME.

Eye Brain. 2011;3:19-28. Epub 2011 Sep 27.


Vision: New light on allergy receptor.

Grant M.

Nature. 2009 Jul 9;460(7252):182-3. doi: 10.1038/460182a. No abstract available.


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