Similar articles for PMID: 21916458

Year	Number of Results
2000	3
2001	2
2004	1
2005	4
2006	1
2007	2
2008	2
2009	4
2010	6
2011	8
2012	12
2013	6
2014	12
2015	10
2016	5
2017	6
2018	7
2019	8
2020	10
2021	6
2022	5
2023	1
2024	0

1

Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins.

Sinha S, Lopes DH, Du Z, Pang ES, Shanmugam A, Lomakin A, Talbiersky P, Tennstaedt A, McDaniel K, Bakshi R, Kuo PY, Ehrmann M, Benedek GB, Loo JA, Klärner FG, Schrader T, Wang C, Bitan G. Sinha S, et al. J Am Chem Soc. 2011 Oct 26;133(42):16958-69. doi: 10.1021/ja206279b. Epub 2011 Sep 29. J Am Chem Soc. 2011. PMID: 21916458 Free PMC article.

2

Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01.

Sinha S, Du Z, Maiti P, Klärner FG, Schrader T, Wang C, Bitan G. Sinha S, et al. ACS Chem Neurosci. 2012 Jun 20;3(6):451-8. doi: 10.1021/cn200133x. Epub 2012 Mar 7. ACS Chem Neurosci. 2012. PMID: 22860214 Free PMC article.

3

Mechanism of Inhibition of Beta Amyloid Toxicity by Supramolecular Tweezers.

Mittal S, Bravo-Rodriguez K, Sanchez-Garcia E. Mittal S, et al. J Phys Chem B. 2018 Apr 19;122(15):4196-4205. doi: 10.1021/acs.jpcb.7b10530. Epub 2018 Apr 9. J Phys Chem B. 2018. PMID: 29630377

4

Amyloid β-protein assembly: The effect of molecular tweezers CLR01 and CLR03.

Zheng X, Liu D, Klärner FG, Schrader T, Bitan G, Bowers MT. Zheng X, et al. J Phys Chem B. 2015 Apr 9;119(14):4831-41. doi: 10.1021/acs.jpcb.5b00692. Epub 2015 Mar 16. J Phys Chem B. 2015. PMID: 25751170 Free PMC article.

5

Toxicity inhibitors protect lipid membranes from disruption by Aβ42.

Malishev R, Nandi S, Kolusheva S, Levi-Kalisman Y, Klärner FG, Schrader T, Bitan G, Jelinek R. Malishev R, et al. ACS Chem Neurosci. 2015 Nov 18;6(11):1860-9. doi: 10.1021/acschemneuro.5b00200. Epub 2015 Sep 9. ACS Chem Neurosci. 2015. PMID: 26317327

6

Protection of primary neurons and mouse brain from Alzheimer's pathology by molecular tweezers.

Attar A, Ripoli C, Riccardi E, Maiti P, Li Puma DD, Liu T, Hayes J, Jones MR, Lichti-Kaiser K, Yang F, Gale GD, Tseng CH, Tan M, Xie CW, Straudinger JL, Klärner FG, Schrader T, Frautschy SA, Grassi C, Bitan G. Attar A, et al. Brain. 2012 Dec;135(Pt 12):3735-48. doi: 10.1093/brain/aws289. Epub 2012 Nov 26. Brain. 2012. PMID: 23183235 Free PMC article.

7

Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism.

Lopes DH, Attar A, Nair G, Hayden EY, Du Z, McDaniel K, Dutt S, Bravo-Rodriguez K, Mittal S, Klärner FG, Wang C, Sanchez-Garcia E, Schrader T, Bitan G. Lopes DH, et al. ACS Chem Biol. 2015 Jun 19;10(6):1555-69. doi: 10.1021/acschembio.5b00146. Epub 2015 Apr 16. ACS Chem Biol. 2015. PMID: 25844890

8

Disrupting self-assembly and toxicity of amyloidogenic protein oligomers by "molecular tweezers" - from the test tube to animal models.

Attar A, Bitan G. Attar A, et al. Curr Pharm Des. 2014;20(15):2469-83. doi: 10.2174/13816128113199990496. Curr Pharm Des. 2014. PMID: 23859557 Free PMC article. Review.

9

Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers.

Weil T, Groß R, Röcker A, Bravo-Rodriguez K, Heid C, Sowislok A, Le MH, Erwin N, Dwivedi M, Bart SM, Bates P, Wettstein L, Müller JA, Harms M, Sparrer K, Ruiz-Blanco YB, Stürzel CM, von Einem J, Lippold S, Read C, Walther P, Hebel M, Kreppel F, Klärner FG, Bitan G, Ehrmann M, Weil T, Winter R, Schrader T, Shorter J, Sanchez-Garcia E, Münch J. Weil T, et al. J Am Chem Soc. 2020 Oct 7;142(40):17024-17038. doi: 10.1021/jacs.0c06400. Epub 2020 Sep 28. J Am Chem Soc. 2020. PMID: 32926779 Free PMC article.

10

Molecular tweezers targeting transthyretin amyloidosis.

Ferreira N, Pereira-Henriques A, Attar A, Klärner FG, Schrader T, Bitan G, Gales L, Saraiva MJ, Almeida MR. Ferreira N, et al. Neurotherapeutics. 2014 Apr;11(2):450-61. doi: 10.1007/s13311-013-0256-8. Neurotherapeutics. 2014. PMID: 24459092 Free PMC article.

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