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Items: 1 to 20 of 100

1.

Cyclic RGD peptides interfere with binding of the Helicobacter pylori protein CagL to integrins αVβ3 and α5β1.

Conradi J, Huber S, Gaus K, Mertink F, Royo Gracia S, Strijowski U, Backert S, Sewald N.

Amino Acids. 2012 Jul;43(1):219-32. doi: 10.1007/s00726-011-1066-0. Epub 2011 Sep 14.

PMID:
21915696
2.

An RGD helper sequence in CagL of Helicobacter pylori assists in interactions with integrins and injection of CagA.

Conradi J, Tegtmeyer N, Woźna M, Wissbrock M, Michalek C, Gagell C, Cover TL, Frank R, Sewald N, Backert S.

Front Cell Infect Microbiol. 2012 May 23;2:70. doi: 10.3389/fcimb.2012.00070. eCollection 2012.

3.

H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis.

Yeh YC, Chang WL, Yang HB, Cheng HC, Wu JJ, Sheu BS.

Mol Carcinog. 2011 Oct;50(10):751-9. doi: 10.1002/mc.20753. Epub 2011 Mar 3.

PMID:
21374738
4.

A helical RGD motif promoting cell adhesion: crystal structures of the Helicobacter pylori type IV secretion system pilus protein CagL.

Barden S, Lange S, Tegtmeyer N, Conradi J, Sewald N, Backert S, Niemann HH.

Structure. 2013 Nov 5;21(11):1931-41. doi: 10.1016/j.str.2013.08.018. Epub 2013 Sep 26.

5.

A novel NOD1- and CagA-independent pathway of interleukin-8 induction mediated by the Helicobacter pylori type IV secretion system.

Gorrell RJ, Guan J, Xin Y, Tafreshi MA, Hutton ML, McGuckin MA, Ferrero RL, Kwok T.

Cell Microbiol. 2013 Apr;15(4):554-70. doi: 10.1111/cmi.12055. Epub 2012 Nov 21.

PMID:
23107019
6.

H. pylori CagL-Y58/E59 prime higher integrin α5β1 in adverse pH condition to enhance hypochlorhydria vicious cycle for gastric carcinogenesis.

Yeh YC, Cheng HC, Yang HB, Chang WL, Sheu BS.

PLoS One. 2013 Aug 29;8(8):e72735. doi: 10.1371/journal.pone.0072735. eCollection 2013. Erratum in: PLoS One. 2014;9(6):e101912.

7.

Molecular dissection of protein-protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system.

Koelblen T, Bergé C, Cherrier MV, Brillet K, Jimenez-Soto L, Ballut L, Takagi J, Montserret R, Rousselle P, Fischer W, Haas R, Fronzes R, Terradot L.

FEBS J. 2017 Dec;284(23):4143-4157. doi: 10.1111/febs.14299. Epub 2017 Nov 12.

PMID:
29055076
8.

Adhesion of several cell lines to Helicobacter pylori CagL is mediated by integrin αVβ6 via an RGDLXXL motif.

Barden S, Niemann HH.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1304-15. doi: 10.1016/j.jmb.2015.01.006. Epub 2015 Jan 21.

PMID:
25617764
9.

Role of α5β1 and αvβ3 integrins in relation to adhesion and spreading dynamics of prostate cancer cells interacting with fibronectin under in vitro conditions.

Stachurska A, Elbanowski J, Kowalczyńska HM.

Cell Biol Int. 2012 Oct 1;36(10):883-92. doi: 10.1042/CBI20110522.

PMID:
22686483
10.

Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives.

Galletti P, Soldati R, Pori M, Durso M, Tolomelli A, Gentilucci L, Dattoli SD, Baiula M, Spampinato S, Giacomini D.

Eur J Med Chem. 2014 Aug 18;83:284-93. doi: 10.1016/j.ejmech.2014.06.041. Epub 2014 Jun 19.

PMID:
24973662
11.

Integrin engagement by the helical RGD motif of the Helicobacter pylori CagL protein is regulated by pH-induced displacement of a neighboring helix.

Bonsor DA, Pham KT, Beadenkopf R, Diederichs K, Haas R, Beckett D, Fischer W, Sundberg EJ.

J Biol Chem. 2015 May 15;290(20):12929-40. doi: 10.1074/jbc.M115.641829. Epub 2015 Apr 2.

12.

De novo expression of the integrin alpha5beta1 regulates alphavbeta3-mediated adhesion and migration on fibrinogen.

Ly DP, Zazzali KM, Corbett SA.

J Biol Chem. 2003 Jun 13;278(24):21878-85. Epub 2003 Apr 3.

13.

Crystal structure of CagL from Helicobacter pylori K74 strain.

Choi JM, Choi YH, Sudhanva MS, Devakumar S, Lee KH, Cha JH, Lee SH.

Biochem Biophys Res Commun. 2015 May 15;460(4):964-70. doi: 10.1016/j.bbrc.2015.03.135. Epub 2015 Apr 1.

PMID:
25839651
14.
15.

Cyclic RGD peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.

Marchini M, Mingozzi M, Colombo R, Guzzetti I, Belvisi L, Vasile F, Potenza D, Piarulli U, Arosio D, Gennari C.

Chemistry. 2012 May 14;18(20):6195-207. doi: 10.1002/chem.201200457. Epub 2012 Apr 19.

PMID:
22517378
16.

Cyclic RGD peptide inhibits alpha 4 beta 1 interaction with connecting segment 1 and vascular cell adhesion molecule.

Cardarelli PM, Cobb RR, Nowlin DM, Scholz W, Gorcsan F, Moscinski M, Yasuhara M, Chiang SL, Lobl TJ.

J Biol Chem. 1994 Jul 15;269(28):18668-73.

17.

Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells.

Chang MW, Lo JM, Juan HF, Chang HY, Chuang CY.

PLoS One. 2012;7(5):e37935. doi: 10.1371/journal.pone.0037935. Epub 2012 May 24.

18.

Helicobacter exploits integrin for type IV secretion and kinase activation.

Kwok T, Zabler D, Urman S, Rohde M, Hartig R, Wessler S, Misselwitz R, Berger J, Sewald N, König W, Backert S.

Nature. 2007 Oct 18;449(7164):862-6.

PMID:
17943123
19.

Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner.

Jiménez-Soto LF, Kutter S, Sewald X, Ertl C, Weiss E, Kapp U, Rohde M, Pirch T, Jung K, Retta SF, Terradot L, Fischer W, Haas R.

PLoS Pathog. 2009 Dec;5(12):e1000684. doi: 10.1371/journal.ppat.1000684. Epub 2009 Dec 4.

20.

Helicobacter pylori exploits cholesterol-rich microdomains for induction of NF-kappaB-dependent responses and peptidoglycan delivery in epithelial cells.

Hutton ML, Kaparakis-Liaskos M, Turner L, Cardona A, Kwok T, Ferrero RL.

Infect Immun. 2010 Nov;78(11):4523-31. doi: 10.1128/IAI.00439-10. Epub 2010 Aug 16.

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